Microfluidic assembly of mono-dispersed liposome and its surface modification for enhancing the colloidal stability

Author(s):  
Minje Jo ◽  
Kyung-Min Park ◽  
Jun-Young Park ◽  
Hyunjong Yu ◽  
Seung Jun Choi ◽  
...  
2013 ◽  
Vol 25 (10) ◽  
pp. 2035-2044 ◽  
Author(s):  
Jothirmayanantham Pichaandi ◽  
Keith A. Abel ◽  
Noah J. J. Johnson ◽  
Frank C. J. M. van Veggel

Author(s):  
Anis Arisa Roslan ◽  
Hasnah Mohd Zaid ◽  
Siti Nur Azella Zaine ◽  
Mursyidah Umar ◽  
Beh Hoe Guan

Nanofluid contains nanoparticles that enhanced the property of the base fluid. However, the separating layer between the nanoparticles and base fluids may interfere the nanofluids performance. Studies have been made that surface modification of nanoparticles may improve the dispersion of nanoparticles in base fluids. This paper reports the study of the colloidal stability of surface modified nanoparticles using a polymer and an amino-silane. The nanoparticles were prepared by one-step and two-step methods using cobalt iron oxide nanoparticles with brine solution and deionized water as the base fluids. Functionalization by surface modification of the nanoparticles to enhance the nanofluids stability was carried out using (3-aminopropyl) triethoxysilane (APTES) and polyvinyl alcohol (PVA). Characterization using Fourier Transform Infrared (FTIR), Field Emission Scanning Electron Microscope (FESEM) and X-ray Powder Diffraction (XRD) were performed to study the functionality and morphology of the synthesized nanoparticles. The extra IR peaks such as Si-O-Si at 1063 cm-1 for CoFe2O4-APTES and C=O at 1742 cm-1 for CoFe2O4-PVA showed that there are additional elements in the cobalt ferrite due to functionalization. The size of synthesized CoFe2O4-APTES ranged between 15.99 nm to 26.89 nm while CoFe2O4-PVA is from 25.70 nm to 54.16 nm. The stability of the nanofluid were determined via zeta potential measurements. CoFe2O4-APTES nanofluid has zeta potential of -35.7 mV compared to CoFe2O4-PVA at -15.5 mV.


Nanomedicine ◽  
2019 ◽  
Vol 14 (23) ◽  
pp. 3035-3055 ◽  
Author(s):  
Gabriel Alfranca ◽  
Lilianne Beola ◽  
Yanlei Liu ◽  
Lucía Gutiérrez ◽  
Amin Zhang ◽  
...  

Aim: To study the difference in biodistribution of gold nanoprisms (NPr) and nanorods (NR), PEGylated to ensure colloidal stability. Materials & methods: Surface changes were studied for nanoparticles in different media, while the biodistribution was quantified and imaged in vivo. Results: Upon interaction with the mouse serum, NR showed more abrupt changes in surface properties than NPr. In the in vivo tests, while NPr accumulated similarly in the spleen and liver, NR showed much higher gold presence in the spleen than in liver; together with some accumulation in kidneys, which was nonexistent in NPr. NPr were cleared from the tissues 2 months after administration, while NR were more persistent. Conclusion: The results suggest that the differential biodistribution is caused by size-/shape-dependent interactions with the serum.


JOM ◽  
2005 ◽  
Vol 57 (12) ◽  
pp. 52-56 ◽  
Author(s):  
Satyanarayana VNT Kuchibhatla ◽  
A. S. Karakoti ◽  
Sudipta Seal

Nanoscale ◽  
2015 ◽  
Vol 7 (4) ◽  
pp. 1403-1410 ◽  
Author(s):  
Stefan Wilhelm ◽  
Martin Kaiser ◽  
Christian Würth ◽  
Josef Heiland ◽  
Carolina Carrillo-Carrion ◽  
...  

2015 ◽  
Vol 232 ◽  
pp. 111-145 ◽  
Author(s):  
Tokeer Ahmad ◽  
Ruby Phul

Superparamagnetic Iron oxide nanoparticles (SPIONs) have fascinated researchers due to their vast applications in biomedical fields such as magnetic resonance imaging, cell sorting, hyperthermia, drug delivery etc. The special properties of SPIONs depend on the method of synthesis and surface modification. Among various synthetic protocols, hydrothermal method has attracted much attention due to simplicity, uniformity and excellent magnetic properties of iron oxide nanoparticles. Magnetic properties of SPIONs could be tuned by controlling the size and shape of the particles as well as by the surface modification. Low colloidal stability and high hydrophobic nature of SPIONs result in aggregation of the particles which could be avoided by surface modification of the SPIONs using various capping agents. The size, shape and surface environment of SPIONs can also be controlled by the surface coating. SPIONs are promising contrast agents due to their non-poisonous nature, biocompatibility and large surface area. The biocompatibility of SPIONs is enhanced by the surface coating/modification. The present review focuses on the hydrothermal synthesis of SPIONs and their characterization using various techniques and the applications of SPIONs in the MRI.Table of Contents


Soft Matter ◽  
2021 ◽  
Author(s):  
Mostafa Ahmadi ◽  
Donya Monji ◽  
Faramarz Afshar Taromi

Bio-inspire surface modification of iron oxide nanoparticles with dopamine promotes the colloidal stability and integrates new transient bonds with PVA chains.


Langmuir ◽  
2017 ◽  
Vol 34 (1) ◽  
pp. 154-163 ◽  
Author(s):  
Jiaojie Tan ◽  
Tae Joon Cho ◽  
De-Hao Tsai ◽  
Jingyu Liu ◽  
John M. Pettibone ◽  
...  

Author(s):  
R. A. Sperling ◽  
W. J. Parak

Inorganic colloidal nanoparticles are very small, nanoscale objects with inorganic cores that are dispersed in a solvent. Depending on the material they consist of, nanoparticles can possess a number of different properties such as high electron density and strong optical absorption (e.g. metal particles, in particular Au), photoluminescence in the form of fluorescence (semiconductor quantum dots, e.g. CdSe or CdTe) or phosphorescence (doped oxide materials, e.g. Y 2 O 3 ), or magnetic moment (e.g. iron oxide or cobalt nanoparticles). Prerequisite for every possible application is the proper surface functionalization of such nanoparticles, which determines their interaction with the environment. These interactions ultimately affect the colloidal stability of the particles, and may yield to a controlled assembly or to the delivery of nanoparticles to a target, e.g. by appropriate functional molecules on the particle surface. This work aims to review different strategies of surface modification and functionalization of inorganic colloidal nanoparticles with a special focus on the material systems gold and semiconductor nanoparticles, such as CdSe/ZnS. However, the discussed strategies are often of general nature and apply in the same way to nanoparticles of other materials.


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