Influence of silane functionalized nanoclay on the barrier, mechanical and hydrophobic properties by clay nanocomposite films in an aggressive chloride medium

In this present work, chitosan (CS) crosslink with polyaniline (PANI) with montmorilonite (MMT) called as (CSPANI/MMT) and CS crosslink with PANI without MMT called as (CS-PANI) were prepared by employing the solution casting method. Further the formation of nanocomposites CS-PANI/MMT and CS-PANI were investigated using XRD, FTIR, SEM and tensile strength. Water uptake and swelling ratio of the CS-PANI and CS-PANI/MMT were found to decrease with increase in concentration of clay. Mechanical properties of the CS-PANI and CS-PANI/MMT were assessed in terms of tensile strength and extensibility using texture analyzer. Increase in tensile strength and reduction in extensibility was reported with increase in the nanoclay content. In vitro drug release study on CS-PANI and CS-PANI/MMT indicated pronounced sustained release of doxorubicin by the incorporation of clay particles in the CS polymer matrix. Overall CSPANI/MMT nanocomposite films exhibited improved mechanical and sustained drug release properties than CS-PANI.

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Nanocomposites: - A Recent Overview

Global Journal of Medical Research ◽

10.34257/gjmrbvol20is7pg9 ◽

2020 ◽

pp. 9-21

Author(s):

Pavan C ◽

Madhavi BLR

Keyword(s):

Targeted Drug Delivery ◽

Current Trend ◽

Nanocomposite Films ◽

Cancer Drug ◽

Preparation Methods ◽

Standard Material ◽

Global Issues ◽

Sustainable Solutions ◽

Anti Cancer ◽

Treatment And Diagnosis

Nanocomposites are substances that incorporate nanoparticles (0.5-5% by weight) into a matrix of standard material, which enhances the mechanical strength, toughness including thermal or electrical conductivity and other properties. Nanocomposites are versatile in terms of their applications such as anti-corrosive, healing of bones, sensors, environmental protection, packaging, wastewater treatment, and diagnosis of tumors and other diverse uses. They may be fabricated by blending nanofillers with a polymer to produce a composite. The current trend of processing is by polymerizing monomers. Nanocomposites serve as sustainable solutions to curb global issues. Evaluation is performed on properties such as mechanical, thermal, dispersion, and toxicological. Some marketed products of nanocomposites include In Mat (coating), FiltekZ350 XT by 3M (tooth fillers), chitosan/organic rectorite nanocomposite films (bactericidal activity), graphene oxide/Carboxymethylcellulose (targeted drug delivery of anti-cancer drug doxorubicin), MD1 Flex, Nano Clean MD1, Plactive TM (Antimicrobial nanocomposites) and NovaProTM(Tooth fillers). This article discusses about Nanocomposites–their types, preparation methods, recent research and applications.

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