Nanocomposites: - A Recent Overview

Author(s):  
Pavan C ◽  
Madhavi BLR

Nanocomposites are substances that incorporate nanoparticles (0.5-5% by weight) into a matrix of standard material, which enhances the mechanical strength, toughness including thermal or electrical conductivity and other properties. Nanocomposites are versatile in terms of their applications such as anti-corrosive, healing of bones, sensors, environmental protection, packaging, wastewater treatment, and diagnosis of tumors and other diverse uses. They may be fabricated by blending nanofillers with a polymer to produce a composite. The current trend of processing is by polymerizing monomers. Nanocomposites serve as sustainable solutions to curb global issues. Evaluation is performed on properties such as mechanical, thermal, dispersion, and toxicological. Some marketed products of nanocomposites include In Mat (coating), FiltekZ350 XT by 3M (tooth fillers), chitosan/organic rectorite nanocomposite films (bactericidal activity), graphene oxide/Carboxymethylcellulose (targeted drug delivery of anti-cancer drug doxorubicin), MD1 Flex, Nano Clean MD1, Plactive TM (Antimicrobial nanocomposites) and NovaProTM(Tooth fillers). This article discusses about Nanocomposites–their types, preparation methods, recent research and applications.

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69083-69093 ◽  
Author(s):  
Jin-Long Wu ◽  
Xiao-Yan He ◽  
Pei-Yuan Jiang ◽  
Meng-Qing Gong ◽  
Ren-Xi Zhuo ◽  
...  

A tumor targeted nano-sized self-assembled drug delivery system could efficiently co-deliver an anti-cancer drug and a drug resistance inhibitor to tumor cells and achieve an improved therapeutic efficiency through inhibition of P-gp function.


Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki

2010 ◽  
Author(s):  
N. Magnavita ◽  
I. lavicoli ◽  
V. Leso ◽  
A. Bergamaschi

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.


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