The role of the fornix in human navigational learning

The role of route and survey information on the gradual acquisition of spatial knowledge was examined in a virtual environment (VE). Navigational focus was induced by having participants learn the environment using either an opaque (route) or transparent (survey) VE. Goal focus was induced by requiring participants to train to a sequential listing (route) or map-based (survey) criterion. During initial training, the presence of a route focus, based on the environment or the stated goal, led to better performance on a survey task than an exclusively survey focus. With increased training, performance with a survey-based focus matched that with a route-based focus. Early stage navigational learning in a survey-based environment benefited from the presence of a route goal. Later stage learning resulted in similar performance between route and survey goals and navigational learning environments.

Download Full-text

Adult-born neurons promote cognitive flexibility by improving memory precision and indexing

10.1101/2020.08.10.242966 ◽

2020 ◽

Author(s):

Gabriel Berdugo-Vega ◽

Chi-Chieh Lee ◽

Alexander Garthe ◽

Gerd Kempermann ◽

Federico Calegari

Keyword(s):

Stem Cells ◽

Dentate Gyrus ◽

Cognitive Flexibility ◽

Spatial Information ◽

Differential Regulation ◽

Memory Representations ◽

Adult Born Neurons ◽

Navigational Learning ◽

Memory Precision

SUMMARYThe dentate gyrus (DG) of the hippocampus is fundamental for cognitive flexibility and has the extraordinary ability to generate new neurons throughout life. Recent evidence suggested that adult-born neurons differentially modulate input to the DG during the processing of spatial information and novelty. However, how this differential regulation by neurogenesis is translated into different aspects contributing cognitive flexibility is unclear. Here, we increased adult-born neurons by a genetic expansion of neural stem cells and studied their influence during navigational learning. We found that increased neurogenesis improved memory precision, indexing and retention and that each of these gains was associated with a differential activation of specific DG compartments and better separation of memory representations in the DG-CA3 network. Our results highlight the role of adult-born neurons in promoting memory precision in the infrapyramidal and indexing in the suprapyramidal blade of the DG and together contributing to cognitive flexibility.One sentence summaryNeurogenesis improves memory precision and indexing.

Download Full-text

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽

10.1001/jama.195.12.1005 ◽

1966 ◽

Vol 195 (12) ◽

pp. 1005-1009 ◽

Cited By ~ 18

Author(s):

D. J. Fernbach

Keyword(s):

Wilms Tumor

Download Full-text

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽

10.1001/jama.195.3.167 ◽

1966 ◽

Vol 195 (3) ◽

pp. 167-172 ◽

Cited By ~ 2

Author(s):

T. E. Van Metre

Keyword(s):

Diagnosis And Management

Download Full-text

The power of norms to sway fused group members

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001644 ◽

2018 ◽

Vol 41 ◽

Cited By ~ 1

Author(s):

Winnifred R. Louis ◽

Craig McGarty ◽

Emma F. Thomas ◽

Catherine E. Amiot ◽

Fathali M. Moghaddam

Keyword(s):

Evolutionary Anthropology ◽

Normative Systems ◽

Violent Extremism ◽

Identity Fusion ◽

Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

Download Full-text

Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

Behavioral and Brain Sciences ◽

10.1017/s0140525x18000274 ◽

2018 ◽

Vol 41 ◽

Author(s):

Kevin Arceneaux

Keyword(s):

Decision Making ◽

Individual Differences ◽

Cognitive Processes ◽

Evolutionary History ◽

Behavioral Responses ◽

History Of ◽

Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

Download Full-text

The role of affect in feelings of obligation

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002449 ◽

2020 ◽

Vol 43 ◽

Author(s):

Stefen Beeler-Duden ◽

Meltem Yucel ◽

Amrisha Vaish

Keyword(s):

Positive Emotions ◽

The Creation ◽

Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

Download Full-text

Refining our understanding of the “elephant in the room”

Behavioral and Brain Sciences ◽

10.1017/s0140525x20000096 ◽

2020 ◽

Vol 43 ◽

Author(s):

Andrew Whiten

Keyword(s):

Social Cognition ◽

Cultural Evolution ◽

Cognitive Abilities ◽

Critical Factors ◽

Technological Culture

Abstract The authors do the field of cultural evolution a service by exploring the role of non-social cognition in human cumulative technological culture, truly neglected in comparison with socio-cognitive abilities frequently assumed to be the primary drivers. Some specifics of their delineation of the critical factors are problematic, however. I highlight recent chimpanzee–human comparative findings that should help refine such analyses.

Download Full-text

Choosing a Markov blanket

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002632 ◽

2020 ◽

Vol 43 ◽

Author(s):

Thomas Parr

Keyword(s):

Markov Blanket ◽

Target Article ◽

The Relationship

Abstract This commentary focuses upon the relationship between two themes in the target article: the ways in which a Markov blanket may be defined and the role of precision and salience in mediating the interactions between what is internal and external to a system. These each rest upon the different perspectives we might take while “choosing” a Markov blanket.

Download Full-text

Alpha-Effect, Current and Kinetic Helicities for Magnetically Driven Turbulence, and Solar Dynamo

International Astronomical Union Colloquium ◽

10.1017/s0252921100064885 ◽

2000 ◽

Vol 179 ◽

pp. 387-388

Author(s):

Gaetano Belvedere ◽

V. V. Pipin ◽

G. Rüdiger

Keyword(s):

Southern Hemisphere ◽

Northern Hemisphere ◽

Convection Zone ◽

Solar Surface ◽

Momentum Transport ◽

Angular Momentum Transport ◽

Magnetic Buoyancy ◽

Alpha Effect ◽

Current Helicity

Extended AbstractRecent numerical simulations lead to the result that turbulence is much more magnetically driven than believed. In particular the role ofmagnetic buoyancyappears quite important for the generation ofα-effect and angular momentum transport (Brandenburg & Schmitt 1998). We present results obtained for a turbulence field driven by a (given) Lorentz force in a non-stratified but rotating convection zone. The main result confirms the numerical findings of Brandenburg & Schmitt that in the northern hemisphere theα-effect and the kinetic helicityℋkin= 〈u′ · rotu′〉 are positive (and negative in the northern hemisphere), this being just opposite to what occurs for the current helicityℋcurr= 〈j′ ·B′〉, which is negative in the northern hemisphere (and positive in the southern hemisphere). There has been an increasing number of papers presenting observations of current helicity at the solar surface, all showing that it isnegativein the northern hemisphere and positive in the southern hemisphere (see Rüdigeret al. 2000, also for a review).

Download Full-text