Identification and primary application of hybridomas cell secreting monoclonal antibodies against mink (Neovison vison) interferon-gamma

Cytokine ◽  
2022 ◽  
Vol 150 ◽  
pp. 155777
Author(s):  
Hailing Zhang ◽  
Shasha Zhang ◽  
Sining Fan ◽  
Lei Zhang ◽  
Bo Hu ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Neovison Vison

Monoclonal antibodies to guinea pig interferon-gamma: Tools for cytokine detection and neutralization

2007 ◽  
Vol 328 (1-2) ◽  
pp. 106-117 ◽  
Author(s):  
H. Schäfer ◽  
G. Kliem ◽  
B. Kropp ◽  
R. Burger
Keyword(s):  
Monoclonal Antibodies ◽  
Guinea Pig ◽  
Interferon Gamma ◽  
Cytokine Detection

Immunohistochemical changes in ovaries caused by chemoimmunotherapy.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e17038-e17038
Author(s):  
Evgeniya M. Nepomnyashchaya ◽  
Galina Andreevna Nerodo ◽  
Anna Ardzha ◽  
Inna Arnoldovna Novikova ◽  
Elena Petrovna Ulianova ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Detection System ◽  
Morphological Changes ◽  
Health Condition ◽  
Ki 67 ◽  
Group A ◽  
Grade Ii ◽  
Group B ◽  
Disease Stages

e17038 Background: The purpose of the study was to analyze morphological and immunohistochemical changes in patients with ovarian serous carcinomas under the influence of chemoimmunotherapy. Methods: The study included patients aged 52-76 years with stage IIIC-IV ovarian cancer with ascites. The patients were divided into two groups according to the treatment received: group A – 22 patients receiving neoadjuvant chemoimmunotherapy, 500 000 IU interferon-gamma (ingaron) on the 1st day and 1 000 000 IU on days 2, 3 and 5, and chemotherapy (carboplatin AUC-6 and paclitaxel 175 mg/m2) on day 4; group B – 24 patients receiving neoadjuvant chemoimmunotherapy and the same regimen of intraperitoneal interferon-gamma. The patients in two groups were similar in terms of disease stages, health condition and age. All patients received further surgery. Immunohistochemical study was performed on paraffin sections for the standard morphological study using Ki-67 rabbit monoclonal antibodies (Thermo scientific) and P-53 mouse monoclonal antibodies (Cell Marque). UltraVision Quanto Detection System HRP DAB was used for visualization. Results: Chemoimmunotherapy plus intraperitoneal interferon-gamma resulted in grade III-IV pathomorphosis, decreased apoptosis index and proliferation activity (р53 – 19.3±2.5%; Ki-67 – 6.2±0.58%) in comparison with the group receiving intramuscular interferon-gamma (р53 –27.6±3.11%; Ki-67 – 16.2±3.09%). The group with chemotherapy and intramuscular interferon-gamma showed grade II pathomorphosis. Conclusions: The study showed that chemotherapy with intraperitoneal interferon-gamma administration, compared with intramuscular one, resulted in more enhanced morphological changes.

Study of antigenic epitopes recognized by monoclonal antibodies to recombinant interferon-gamma

1985 ◽  
Vol 128 (1) ◽  
pp. 171-178 ◽  
Author(s):  
Chi-Ming Liang ◽  
Suzanne Herren ◽  
Astrid Sand ◽  
Therese Jost
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Recombinant Interferon ◽  
Antigenic Epitopes

Monoclonal Antibodies as Structural Probes for Oligomeric Human Interferon-Gamma

1985 ◽  
Vol 5 (3) ◽  
pp. 445-453 ◽  
Author(s):  
JUNMING LE ◽  
TSE WEN CHANG ◽  
VICTOR LIU ◽  
YUM K. YIP ◽  
JAN VILCEK
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Human Interferon ◽  
Structural Probes

scholarly journals Monoclonal antibodies to human interferon-gamma: production, affinity purification and radioimmunoassay.

1983 ◽  
Vol 2 (9) ◽  
pp. 1527-1530 ◽  
Author(s):  
D. Novick ◽  
Z. Eshhar ◽  
D.G. Fischer ◽  
J. Friedlander ◽  
M. Rubinstein
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Affinity Purification ◽  
Human Interferon

scholarly journals Characterization of Mouse Monoclonal Antibodies to Human Interferon-Gamma

1988 ◽  
Vol 32 (4) ◽  
pp. 339-350 ◽  
Author(s):  
Yoko Yamamoto ◽  
Keizo Miyata ◽  
Masamichi Ueda ◽  
Yoshimi Kawade ◽  
Kayoko Matsumoto ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Interferon Gamma ◽  
Human Interferon

SYNERGISTIC IMMUNOSUPPRESSIVE EFFECTS OF MONOCLONAL ANTIBODIES SPECIFIC FOR INTERFERON-GAMMA AND TUMOR NECROSIS FACTOR ALPHA

1990 ◽  
Vol 50 (5) ◽  
pp. 856-861 ◽  
Author(s):  
HIERONYMUS P. J. D. STEVENS ◽  
THEODORUS H. VAN DER KWAST ◽  
PETER H. VAN DER MEIDE ◽  
VOJISLAV D. VUZEVSKI ◽  
WIM A. BUURMAN ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Interferon Gamma ◽  
Tumor Necrosis ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor
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