Association of total VLDL particle concentrations with elevated blood viscosity in patients with type 2 diabetes

2021 ◽  
pp. 109180
Author(s):  
Robert S. Rosenson ◽  
Martin L. Lee ◽  
Qinzhong Chen
Keyword(s):  
Type 2 Diabetes ◽  
Blood Viscosity ◽  
Elevated Blood ◽  
Vldl Particle

scholarly journals An Obesity-RelatedFTOVariant and the Risk of Preeclampsia in a Finnish Study Population

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Miira Klemetti ◽  
Leena M. Hiltunen ◽  
Sanna Heino ◽  
Seppo Heinonen ◽  
Eero Kajantie ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Early Onset ◽  
Elevated Blood ◽  
Study Population ◽  
Normotensive Pregnancy ◽  
Finnish Study ◽  
Risk Of Preeclampsia

Previous studies have demonstrated a common variant of the obesity and fat mass-relatedFTOgene, rs9939609, to be associated with obesity, type 2 diabetes, and elevated blood pressure. We investigated whether theFTOSNP rs9939609 is associated with the risk of preeclampsia (PE) in a Finnish study population. 485 women with prior PE and 449 women who had given birth after a normotensive pregnancy were genotyped (TaqMan) for the SNP rs9939609. The prevalences of genotypes AA, AT, and TT were 15%, 53%, and 32%, respectively, among the PE cases, and 16%, 47%, and 37%, respectively, among the controls (P=0.199). We found no evidence of an association between theFTOSNP rs9939609 and PE. However, our cases were dominated by severe, early-onset PE. Thus, we are unable to exclude an association with the milder, later-onset form of the disease in which the role of maternal metabolic predisposition could be more significant.Erratum to “An Obesity-RelatedFTOVariant and the Risk of Preeclampsia in a Finnish Study Population”

scholarly journals Gastrointestinal Mechanisms Underlying the Cardiovascular Effect of Metformin

2020 ◽  
Vol 13 (11) ◽  
pp. 410
Author(s):  
Malcolm J. Borg ◽  
Christopher K. Rayner ◽  
Karen L. Jones ◽  
Michael Horowitz ◽  
Cong Xie ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Risk ◽  
Cardiovascular Effect ◽  
Elevated Blood ◽  
Direct Effects ◽  
Mechanistic Studies ◽  
Glucose Lowering ◽  
Glucose Levels ◽  
Blood Glucose Levels

Metformin, the most widely prescribed drug therapy for type 2 diabetes, has pleiotropic benefits, in addition to its capacity to lower elevated blood glucose levels, including mitigation of cardiovascular risk. The mechanisms underlying the latter remain unclear. Mechanistic studies have, hitherto, focused on the direct effects of metformin on the heart and vasculature. It is now appreciated that effects in the gastrointestinal tract are important to glucose-lowering by metformin. Gastrointestinal actions of metformin also have major implications for cardiovascular function. This review summarizes the gastrointestinal mechanisms underlying the action of metformin and their potential relevance to cardiovascular benefits.

Effect of postprandial hyperglycaemia on blood viscosity in aged patients suffering from type 2 diabetes as compared with healthy volunteers

2007 ◽  
Vol 18 (8) ◽  
pp. 745-750 ◽  
Author(s):  
Ludovico Coppola ◽  
Teresa Cerciello ◽  
Paraskevula Boviatsi ◽  
Agostino Pastore ◽  
Antonino Coppola ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Healthy Volunteers ◽  
Blood Viscosity ◽  
Postprandial Hyperglycaemia ◽  
Aged Patients

Association among low whole blood viscosity, haematocrit, haemoglobin and diabetic retinopathy in subjects with type 2 diabetes

2010 ◽  
Vol 95 (1) ◽  
pp. 94-98 ◽  
Author(s):  
C. Irace ◽  
F. Scarinci ◽  
V. Scorcia ◽  
D. Bruzzichessi ◽  
R. Fiorentino ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Whole Blood Viscosity

scholarly journals Empagliflozin influences blood viscosity and wall shear stress in subjects with type 2 diabetes mellitus compared with incretin-based therapy

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Concetta Irace ◽  
Francesco Casciaro ◽  
Faustina Barbara Scavelli ◽  
Rosa Oliverio ◽  
Antonio Cutruzzolà ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Shear Stress ◽  
Type 2 Diabetes Mellitus ◽  
Wall Shear Stress ◽  
Blood Viscosity ◽  
Wall Shear

Elevated blood apelin levels in type 2 diabetes mellitus: A systematic review and meta-analysis

2019 ◽  
Vol 148 ◽  
pp. 43-53 ◽  
Author(s):  
Ali Noori-Zadeh ◽  
Salar Bakhtiyari ◽  
Shokoufeh Khanjari ◽  
Karimeh Haghani ◽  
Shahram Darabi
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Meta Analysis ◽  
Elevated Blood
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