Data on the relationship of signal-to-cutoff ratio of two HIV antigen/antibody combination assays to subsequent confirmation of HIV-1 infection in a low-prevalence population

Microagglutination tests were used to show the relationship of a nongroupable strain of Neisseria meningitidis (RAS-10) to other serological groups. RAS-10 antiserum has been prepared and studied for the first time. Antibodies to the RAS-10 strain were shown to be present in many grouping antisera obtained from different sources. These antibodies were absorbed from antisera to heterologous sero-groups with the RAS-10 strain. This procedure was shown to make antisera more specific by eliminating serological cross-reactions and false grouping of RAS-10 strains. Antisera before and after absorption with RAS-10 cells were studied by using double diffusion in gels. An antigen-antibody precipitation line for the RAS-10 meningococci was shown to be removed by this procedure. Antiserum to group 29E meningococci was absorbed with group Z cells, and precipitation lines for Z cells were removed. Group 29E antiserum agglutinated group 29E and group Z cells in the slide agglutination test but was specific for group 29E cells in this test after absorption with group Z cells.

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The Relationship of Preventable Opportunistic Infections, HIV-1 RNA, and CD4 Cell Counts to Chronic Mortality

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/00042560-200208010-00008 ◽

2002 ◽

Vol 30 (4) ◽

pp. 421-428 ◽

Cited By ~ 18

Author(s):

George R. Seage ◽

Elena Losina ◽

Sue J. Goldie ◽

A. David Paltiel ◽

April D. Kimmel ◽

...

Keyword(s):

Opportunistic Infections ◽

Cell Counts ◽

Cd4 Cell Counts ◽

Relationship Of ◽

Cd4 Cell ◽

The Relationship ◽

Hiv 1

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Prevalence of serological markers and risk factors for bloodborne pathogens in Salvador, Bahia state, Brazil

Epidemiology and Infection ◽

10.1017/s0950268812000386 ◽

2012 ◽

Vol 141 (1) ◽

pp. 181-187 ◽

Cited By ~ 4

Author(s):

S. B. MATOS ◽

A. L. S. R. JESUS ◽

K. C. M. C. PEDROZA ◽

H. R. S. SODRE ◽

T. L. H. FERREIRA ◽

...

Keyword(s):

Risk Factors ◽

Sexual Partner ◽

Infectious Agents ◽

Serological Markers ◽

Bloodborne Pathogens ◽

Relationship Of ◽

The Relationship ◽

Anti Hiv ◽

Steady Sexual Partner ◽

Hiv 1

SUMMARYThis study aimed to determine the prevalence of serological markers for HIV-1/2, HBV, HCV, Treponema cruzi and T. pallidum infections. The association of these infections with risk factors in a population from Salvador, Bahia, Brazil was also analysed. Of the 780 enrolled individuals, 545 (70%) were female and 235 (30%) were male. Seroprevalence of 0·8% (6/702), 1·3% (9/678), 1·5% (10/684), 3·5% (23/663) and 11·5% (77/668) for HIV-1/2, HBV, HCV, T. cruzi and T. pallidum infections, respectively, was observed. The seroprevalence of T. pallidum was higher in males 20% (43/210) than in females 7% (34/458) (P < 0·01). An association between age and seroprevalence for T. cruzi (P = 0·02) and T. pallidum (P < 0·01) was observed. HBsAg was associated with having tattoos (3/37 vs. 6/623, P = 0·01) and not having a steady sexual partner (5/141 vs. 4/473, P = 0·04), while anti-HIV-1/2 was associated with having tattoos (2/39 vs. 4/647, P = 0·04); however, larger studies are needed to categorically state the relationship of these risk factors with infectious agents. The prevalence of serological markers for HIV-1/2, HBV, HCV and T. cruzi was consistent with other studies.

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Further evidence for the relationship of HIV-1 gp120 V3 loops with Ig superfamily members: similarity with the putative CDR3 region of T-cell receptor δ-chains

Immunology Letters ◽

10.1016/0165-2478(95)00056-b ◽

1995 ◽

Vol 47 (1-2) ◽

pp. 25-28 ◽

Cited By ~ 7

Author(s):

R. Metlaš ◽

V. Skerl ◽

V. Veljković ◽

S. Pongor

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Cdr3 Region ◽

Ig Superfamily ◽

Relationship Of ◽

The Relationship ◽

Hiv 1

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A COMPLETE HIV-1 Env CODING SEQUENCES FROM HIV ISOLATED IN CENTRAL JAVA, INDONESIA

KnE Life Sciences ◽

10.18502/kls.v2i1.112 ◽

2015 ◽

Vol 2 (1) ◽

pp. 27

Author(s):

Irvan Raharjo ◽

Afiono Agung Prasetyo

Keyword(s):

Transmembrane Helix ◽

Coding Sequences ◽

Protein Charge ◽

Central Java ◽

Keywords Hiv ◽

Escherichia Coli Expression ◽

Hiv Envelope ◽

Relationship Of ◽

The Relationship ◽

Hiv 1

Background:The HIV envelope glycoprotein (env) plays a central role in viral transmission to target cells.The genetic diversity of env gene contributes a great mechanism on how HIV-1 could survive.Aims:To determine the genotype and genetic relationship of our isolate compared to the other HIV-1 isolates, especially from Indonesia based on the env gene. Also, for further use, the molecular properties of our gene had been analyzed. Methods: A complete coding sequence of HIV-1 env gene was cloned from 09IDSKA-6 (HIV isolated in Central Java, Indonesia), inserted into an Escherichia coli expression plasmid, and sequenced. The sequencing results of the env gene then subjected for virus subtyping and genotyping. The phylogenetic analysis was performed to know the relationship between the isolate with all HIV isolates in Indonesia based on the env gene.The sequencing results were also subjected for bioinformatics analysis.Results: Based on the molecular analysis of HIV-1 env complete coding sequences, the 09IDSKA-6 belong to HIV CRF01_AEwhich is quite common in Southeast Asia. The signal peptide, protein charge, transmembrane helix, antigenicity, hydrophobicity, secondary structure, and proteolytic cleavageof our gene also had been discussed. Keywords: HIV-1, env gene, Indonesia.

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THE RELATIONSHIP OF PREVENTABLE OPPORTUNISTIC INFECTIONS, HIV-1 RNA, AND CD4 CELL COUNTS TO CHRONIC MORTALITY

Infectious Diseases in Clinical Practice ◽

10.1097/00019048-200205000-00050 ◽

2002 ◽

Vol 11 (4) ◽

pp. 264

Author(s):

&NA;

Keyword(s):

Opportunistic Infections ◽

Cell Counts ◽

Cd4 Cell Counts ◽

Relationship Of ◽

Cd4 Cell ◽

The Relationship ◽

Hiv 1

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Prevalence of smoking in nursing professionals of a cardiovascular hospital

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2018-0145 ◽

2019 ◽

Vol 72 (suppl 1) ◽

pp. 173-180 ◽

Cited By ~ 1

Author(s):

Andrea Cotait Ayoub ◽

Márcio Gonçalves Sousa

Keyword(s):

Family Income ◽

Family Background ◽

Demographic Characteristics ◽

Nursing Assistant ◽

Explanatory Variables ◽

History Of ◽

Low Prevalence ◽

Nursing Professionals ◽

Relationship Of ◽

The Relationship

ABSTRACT Objective: to identify the prevalence of smoking in nursing professionals and to determine the relationship of the habit with clinical and socio-demographic characteristics. Method: nursing professionals of a cardiovascular hospital answered a questionnaire on smoking and dependence degree, socio-demographic characteristics, personal and family background, smoking characteristics, motivational stages, depression, perceived and occupational stress. The relationship between the explanatory variables and smoking was investigated. Results: among 656 participants, 77.6% were non smokers, 12.2% former smokers, and 10.2% smokers. Most were female, with complete high school, Catholic, married, household income between three and five minimum wages, position as nursing assistant, had double shifts, and were responsible for family income. The nicotine dependence of smokers ranged from low to moderate. Conclusion: the study has shown low prevalence of smoking in nursing professionals. Education level, religion, marital status, job position, responsibility for family income, history of depression and alcoholism, chest "wheezing" and other symptoms were significantly associated with being a smoker or former smoker.

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THE "DELAYED HYPERSENSITIVITY" INDUCED BY ANTIGEN-ANTIBODY COMPLEXES

Journal of Experimental Medicine ◽

10.1084/jem.108.6.823 ◽

1958 ◽

Vol 108 (6) ◽

pp. 823-841 ◽

Cited By ~ 43

Author(s):

Sidney Raffel ◽

J. Michael Newel

Keyword(s):

Delayed Hypersensitivity ◽

Small Doses ◽

Circulating Antibodies ◽

Antigen Antibody ◽

Relationship Of ◽

The Relationship ◽

Relative Persistence

The "delayed hypersensitive" reactivity induced by antigen-antibody complexes has been studied from the standpoints of the role of such complexes in establishing this state, and the relationship of this state to classical delayed hypersensitivity. It has been shown that the reactivity established by antigen-antibody complexes appears early after injection, disappears within a few days, and is characterized by several properties which make it appear similar to true delayed hypersensitivity, including its appearance, its relative persistence for 48 hours, and its occurrence in the absence of antibodies. By the same tokens, it may be distinguished from hypersensitive reactions of the immediate type. It is referred to here as reactivity of the Jones-Mote type. Antigen alone stimulates exactly the same kind of early reactive state, but with larger doses of antigen this is later replaced by other immunologic responses including circulating antibodies and Arthus reactivity. If sufficiently small doses of antigen are employed, however, the "monophasic" reaction which follows antigen-antibody complexes consisting of the Jones-Mote type of skin responsiveness may be seen. The dermal reactivity under discussion is unlike classical delayed hypersensitivity chiefly in its evanescent character; it is present only during a few days early after antigen administration. It is suggested that this kind of reactivity, which may perhaps require a category of its own, may be related to the "tissue immunity" to tumor transplants which has been observed in mice.

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