scholarly journals A COMPLETE HIV-1 Env CODING SEQUENCES FROM HIV ISOLATED IN CENTRAL JAVA, INDONESIA

2015 ◽  
Vol 2 (1) ◽  
pp. 27
Author(s):  
Irvan Raharjo ◽  
Afiono Agung Prasetyo

Background:The HIV envelope glycoprotein (env) plays a central role in viral transmission to target cells.The genetic diversity of env gene contributes a great mechanism on how HIV-1 could survive.Aims:To determine the genotype and genetic relationship of our isolate compared to the other HIV-1 isolates, especially from Indonesia based on the env gene. Also, for further use, the molecular properties of our gene had been analyzed. Methods: A complete coding sequence of HIV-1 env gene was cloned from 09IDSKA-6 (HIV isolated in Central Java, Indonesia), inserted into an Escherichia coli expression plasmid, and sequenced. The sequencing results of the env gene then subjected for virus subtyping and genotyping. The phylogenetic analysis was performed to know the relationship between the isolate with all HIV isolates in Indonesia based on the env gene.The sequencing results were also subjected for bioinformatics analysis.Results: Based on the molecular analysis of HIV-1 env complete coding sequences, the 09IDSKA-6 belong to HIV CRF01_AEwhich is quite common in Southeast Asia. The signal peptide, protein charge, transmembrane helix, antigenicity, hydrophobicity, secondary structure, and proteolytic cleavageof our gene also had been discussed. Keywords: HIV-1, env gene, Indonesia. 

2002 ◽  
Vol 30 (4) ◽  
pp. 421-428
Author(s):  
George R. Seage ◽  
Elena Losina ◽  
Sue J. Goldie ◽  
A. David Paltiel ◽  
April D. Kimmel ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
pp. 105
Author(s):  
Maryuni Maryuni

Indonesia is the fourth largest contributor to the population in the world after China, India and the United States. The 2017 IHDS showed the total fertility rate (TFR) was 2.4 children per woman. One program to reduce population growth rates and TFR is through the Family Planning (KB) program. This study aims to determine the relationship of education, age and parity to the choice of contraceptive methods for long and short-terms in Tanjung Anom Village, Salaman Subdistrict, Magelang Regency, Central Java Province. This research is descriptive analytic with cross sectional method. The data collection was done in October 2015. The study sample was women of childbearing age who used contraception in both long and short terms, as many as 46 people. The research instrument used was a questionnaire. Data was analyzed by univariate and bivariate. The result of the study showed that there was no significant relationship among education, age and parity towards the choice of both long and non-long contraception methods. The selection of contraceptive method is not only influenced by education, age and parity, but also by Socio-Demographic factors, Socio-Psychological factors, and health services


2018 ◽  
Vol 5 (2) ◽  
pp. 217-225
Author(s):  
Rosyafa Febiandani ◽  
Deky Aji Suseno

Adanya desentralisasi fiskal diharapkan dapat menciptakan kemandirian daerah dan dapat mengurangi ketergantungan pemerintah daerah terhadap pemerintah pusat. Kemandirian keuangan daerah dicerminkan dengan perbandingan besarnya PAD terhadap total pendapatan daerah. Sejak 10 tahun dilaksanakannya otonomi daerah sesuai UU No 32 Tahun 2004, kemandirian keuangan daerah di Provinsi Jawa Tengah masih berada di level yang kurang baik dibandingkan dengan provinsi lainnya di Pulau Jawa. Jumlah pengangguran dan jumlah penduduk miskin di Provinsi Jawa Tengah juga masih terhitung tinggi. Penelitian ini bertujuan untuk mengetahui hubungan dari tingkat kemandirian keuangan daerah dan tingkat ketergantungan daerah terhadap tingkat pengangguran dan tingkat kemiskinan di kabupaten/kota Provinsi Jawa Tengah Tahun 2013. Data yang digunakan dalam penelitian ini adalah data sekunder. Metode analisis yang digunakan adalah Analisis Korelasi Kanonikal menggunakan bantuan program SPSS. Hasil penelitian menunjukkan kemandirian keuangan daerah mempunyi hubungan yang signifikan, kuat, dan tidak searah dengan pengangguran dan kemiskinan. Sedangkan hubungan antara ketergantungan daerah terhadap kemiskinan dan pengangguran mempunyai hubungan yang signifikan, tidak kuat, dan tidak searah. Peningkatan kemandirian keuangan daerah guna mengurangi tingkat ketergantungan terhadap pemerintah pusat dapat dilakukan dengan cara menggali dan mengelola sumber daya atau potensi daerah yang dimilikinya secara efektif dan efisien sebagai sumber utama pendapatan keuangan daerahnya. Fiscal decentralization is expected to create  independency regional financial  and to reduce the dependence of local governments to the central government. Independency regional financial can be result by the ratio of PAD to total local revenue. Since 10 years the implementation of regional autonomy based on UU No. 32 of 2004, independency regional financial in Central Java  is still unwell compared to the other provinces in Java. As well as unemployed, and the poverty in Central Java is still high. The purpose of this research is to determine the relationship of  independency regional financial and the dependency regional to unemployment and poverty in Central Java period 2013. The data used in this research is secondary data. The method of analysis used is the Canonical Correlation Analysis using SPSS application. The results of research showed that the relationship of independency regional financial are significant, strong, and no direct relation with unemployment and poverty The relationship between dependency regional with unemployment and poverty are significant, no strong, and no direct relation. Increased the independency local financial to reduce the dependence on the central government can be done by managing the resources or the potential of region effectively and efficiently as the source from their financial local revenue


2019 ◽  
Vol 6 (2) ◽  
pp. 108-119
Author(s):  
Ruthy Ngapiyem ◽  
Erik Adik Putra Bambang Kurniawan

Latar Belakang : Halusinasi merupakan  gangguan persepsi dimana  pasien mempersepsikan sesuatu  yang sebenarnya tidak terjadi.  Penatalaksanaan keperawatan pada pasien dengan perubahan sensori persepsi: halusinasi selain diberi pengobatan farmakologi juga dengan dukungan keluarga agar dapat mengontrol halusinasi. Keterlibatan pendukung pasien (keluarga) sangat dapat membantu dalam proses pengobatan dalam kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran. Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga dengan kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Metode Penelitian : Penelitian ini menggunakan desain studi korelasi untuk melihat adanya hubungan dukungan keluarga  dengan kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran. Besar sampel dalam penelitian ini mengunakan kriteria sampling sebagai berikut: Populasi < 100 diambil total/ semua sampling. Dalam penelitian ini, jumlah sampelnya berjumlah 40 responden. Hasil Penelitian : Berdasarkan hasil uji statistic chi-square didapatkan nilai P-value > α yaitu (0,356 > 0,05) yang artinya tidak ada hubungan antara dukungan keluarga dengan kemampuan klien mengontrol halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Kesimpulan dan Saran : Tidak ada hubungan antara dukungan keluarga dengan kemampuan klien mengontrol halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Diharapkan bagi peneliti selanjutnya meneliti terkait dengan faktor apa saja yang dapat mendukung kemampuan mengontrol halusinasi pendengaran.   Kata Kunci : dukungan keluarga, halusinasi pendengaran, kemampuan mengontrol halusinasi pendengaran   ABSTRACT   Background: Hallucinations are perceptual disorders where patients perceive something that really doesn't happen. Nursing management in patients with hallucinations besides being given pharmacological treatment also with family support in order to control hallucinations. The involvement of supporting patients (families) can greatly assist in the treatment process in the ability to control auditory hallucinations in auditory hallucinations clients. Objective: This study aims to determine the relationship of family support with the ability to control auditory hallucinations in auditory hallucinations clients at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. Method: This study uses a correlation study design to see the relationship of family support with the ability to control auditory hallucinations in auditory hallucinations clients. The sample size in this study used the following sampling criteria: Population <100 was taken total/ all sampling. In this study, the number of samples was 40 respondents. Result: Based on the results of the chi-square statistical test, the value of P-value> α is obtained (0.356> 0.05) which means there is no relationship between family support and the client's ability to control auditory hallucinations at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. Conclusion and Reccomendation: There is no relationship between family support and the client's ability to control auditory hallucinations at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. It is hoped that the next researcher will examine the related factors that can support the ability to control auditory hallucinations.   Keywords : family support, auditory hallucinations, ability to control auditory hallucinations


2009 ◽  
Vol 8 (1) ◽  
pp. 258 ◽  
Author(s):  
Jean-Pierre Van Geertruyden ◽  
Erika Van Eijk ◽  
Francisca Yosaatmadja ◽  
Webster Kasongo ◽  
Modest Mulenga ◽  
...  

INFERENSI ◽  
2013 ◽  
Vol 7 (1) ◽  
pp. 163
Author(s):  
Moh Khoiruddin ◽  
Andhi Wijayanto

This study aims to determine the relationship of the financial performance of Islamic banks, market orientation, learning orientation, and relational capital. By knowing the kind of relationship would be beneficial for improving the financial performance of Islamic banks which have distinctive core business. The population in this study was the manager of Islamic banks in the province of Central Java. With purposive random sampling, 119 samples are obtained. SEM analysis results show the effect of learning orientation on market orientation, market orientation effect on relational capital, relational capital effects on the financial performance, the effect of learning orientation on financial performance, the effect of market orientation on financial performance is significant. Goodness of Fit value of the model is quite satisfactory.


2002 ◽  
Vol 30 (4) ◽  
pp. 421-428 ◽  
Author(s):  
George R. Seage ◽  
Elena Losina ◽  
Sue J. Goldie ◽  
A. David Paltiel ◽  
April D. Kimmel ◽  
...  

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