Effects of buserelin administration on testicular blood flow and plasma concentrations of testosterone and estradiol-17β in rams

2021 ◽  
pp. 106646
Author(s):  
Amr S. El-Shalofy ◽  
Mohamed G. Hedia
Keyword(s):  
Blood Flow ◽  
Plasma Concentrations ◽  
Testicular Blood Flow ◽  
Estradiol 17Β

An in vivo Model for the Assessment of Acute Fibrinolytic Capacity of the Endothelium

1997 ◽  
Vol 78 (04) ◽  
pp. 1242-1248 ◽  
Author(s):  
David E Newby ◽  
Robert A Wright ◽  
Christopher A Ludlam ◽  
Keith A A Fox ◽  
Nicholas A Boon ◽  
...  
Keyword(s):  
Blood Flow ◽  
Substance P ◽  
Sodium Nitroprusside ◽  
Plasma Concentrations ◽  
In Vivo Model ◽  
Forearm Circulation ◽  
Von Willebrand ◽  
Local Release ◽  
Willebrand Factor

SummaryThe effects on blood flow and plasma fibrinolytic and coagulation parameters of intraarterial substance P, an endothelium dependent vasodilator, and sodium nitroprusside, a control endothelium independent vasodilator, were studied in the human forearm circulation. At subsystemic locally active doses, both substance P (2-8 pmol/min) and sodium nitroprusside (2-8 μg/min) caused dose-dependent vasodilatation (p <0.001 for both) without affecting plasma concentrations of PAI-1, von Willebrand factor antigen or factor VIII:C activity. Substance P caused local increases in t-PA antigen and activity (p <0.001) in the infused arm while sodium nitroprusside did not. At higher doses, substance P increased blood flow and t-PA concentrations in the noninfused arm. We conclude that brief, locally active and subsystemic infusions of intraarterial substance P cause a rapid and substantial local release of t-PA which appear to act via a flow and nitric oxide independent mechanism. This model should provide a useful and selective method of assessing the in vivo capacity of the forearm endothelium to release t-PA acutely.

Acute scrotum and testicular blood flow

Choonpa Igaku ◽  
2014 ◽  
Vol 41 (6) ◽  
pp. 801-810
Author(s):  
Kimihiko MORIYA
Keyword(s):  
Blood Flow ◽  
Acute Scrotum ◽  
Testicular Blood Flow

scholarly journals High Feed Intake Increases Liver Blood Flow and Metabolism of Progesterone and Estradiol-17β in Dairy Cattle

2002 ◽  
Vol 85 (11) ◽  
pp. 2831-2842 ◽  
Author(s):  
S. Sangsritavong ◽  
D.K. Combs ◽  
R. Sartori ◽  
L.E. Armentano ◽  
M.C. Wiltbank
Keyword(s):  
Blood Flow ◽  
Dairy Cattle ◽  
Feed Intake ◽  
Liver Blood Flow ◽  
High Feed ◽  
Estradiol 17Β

Testicular Blood Flow in Monkeys as Measured by Xenon Clearance and Radioactive Microspheres

1985 ◽  
Vol 14 (1) ◽  
pp. 49-55
Author(s):  
Richard M. Harrison ◽  
Ronald W. Lewis ◽  
James A. Roberts
Keyword(s):  
Blood Flow ◽  
Radioactive Microspheres ◽  
Testicular Blood Flow ◽  
Xenon Clearance

scholarly journals Enhanced Nitrite-Mediated Relaxation of Placental Blood Vessels Exposed to Hypoxia Is Preserved in Pregnancies Complicated by Fetal Growth Restriction

2021 ◽  
Vol 22 (9) ◽  
pp. 4500
Author(s):  
Teresa Tropea ◽  
Carina Nihlen ◽  
Eddie Weitzberg ◽  
Jon O. Lundberg ◽  
Mark Wareing ◽  
...  
Keyword(s):  
Blood Flow ◽  
Blood Vessels ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Plasma Concentrations ◽  
Growth Restriction ◽  
Alternative Source ◽  
Fetal Plasma ◽  
Placental Blood ◽  
Nitrate And Nitrite

Nitric oxide (NO) is essential in the control of fetoplacental vascular tone, maintaining a high flow−low resistance circulation that favors oxygen and nutrient delivery to the fetus. Reduced fetoplacental blood flow is associated with pregnancy complications and is one of the major causes of fetal growth restriction (FGR). The reduction of dietary nitrate to nitrite and subsequently NO may provide an alternative source of NO in vivo. We have previously shown that nitrite induces vasorelaxation in placental blood vessels from normal pregnancies, and that this effect is enhanced under conditions of hypoxia. Herein, we aimed to determine whether nitrite could also act as a vasodilator in FGR. Using wire myography, vasorelaxant effects of nitrite were assessed on pre-constricted chorionic plate arteries (CPAs) and veins (CPVs) from normal and FGR pregnancies under normoxic and hypoxic conditions. Responses to the NO donor, sodium nitroprusside (SNP), were assessed in parallel. Nitrate and nitrite concentrations were measured in fetal plasma. Hypoxia significantly enhanced vasorelaxation to nitrite in FGR CPAs (p < 0.001), and in both normal (p < 0.001) and FGR (p < 0.01) CPVs. Vasorelaxation to SNP was also potentiated by hypoxia in both normal (p < 0.0001) and FGR (p < 0.01) CPVs. However, compared to vessels from normal pregnancies, CPVs from FGR pregnancies showed significantly lower reactivity to SNP (p < 0.01). Fetal plasma concentrations of nitrate and nitrite were not different between normal and FGR pregnancies. Together, these data show that nitrite-mediated vasorelaxation is preserved in FGR, suggesting that interventions targeting this pathway have the potential to improve fetoplacental blood flow in FGR pregnancies.

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