scholarly journals Lipid profile in Egyptian patients with coronary artery disease

2013 ◽  
Vol 65 (2) ◽  
pp. 79-85 ◽  
Author(s):  
M. Mohsen Ibrahim ◽  
Ahmed Ibrahim ◽  
Khaldoon Shaheen ◽  
Mona A. Nour
2021 ◽  
Vol 15 (6) ◽  
pp. 1203-1205
Author(s):  
S. Naz ◽  
M. Raza ◽  
A. Akbar ◽  
A. N. Zaidi ◽  
S. Khaliq ◽  
...  

Aim: To evaluate serum Interleukin-6, and lipids as predictors of cardiovascular diseases (CVD) in obese and non obese male patients of coronary artery disease (CAD). Methodology: It was cross-sectional comparative study. Serum Interleukin-6 and lipid profile was determined in non diabetic, non smoker and non hypertensive age matched obese and non obese male patients of CAD and healthy subjects. Sixty male subjects were divided equally into groups. Group 1, healthy controls (n=20), group 2, non obese male patients with CAD (n=20) and group 3 included Obese male patients with CAD (n=20). The serum was assayed for lipid profile and interleukin-6 . Results: Age matched healthy and patients were non diabetics, non hypertensive and non smoker with altered lipid profile in obese and non obese male patients with coronary artery disease. Patients have high serum cholesterol, low density cholesterol(LDL-C), Triglyceride(TG,) very low density lipoprotein(VLDL) and interleukin-6. The High density lipoprotein was lowered in both obese and non obese male patients with CAD. Significant positive correlation was observed in CAD group of IL-6 with TC (rho= 0.405, p= 0.009*) , with TG (rho= 0.639, p= 0.000*) ,with LDL (rho= 0.398, p= 0.002*), with VLDL (rho= 0.315, p= 0.014*). Significant negative correlation was observed in CAD group of IL-6 with HDL (rho= -0.565, p= 0.000*) Significant positive correlation was observed in CAD group of IL-6 .Significant positive correlation of IL-6 was observed with AI (rho= 0.602, p= 0.000*). Conclusion: Dyslipidemia, Raised interleukin-6 and strong positive correlation of Atherogenic index with IL-6 are independent risk factors for CVD; using Atherogenic risk ratios as a screening tool for the estimation of CVD risk is useful in patients with CAD. Keywords: Lipid profile, serum interleukin-6,Atherogenic index,coronary artery disease.


Author(s):  
Sifat Jubaira ◽  
Forhadul Haque Mollah ◽  
Tahrim Mehdi ◽  
M Iqbal Arslan

The study was designed to explore serum copper as a risk factor for coronary artery disease (CAD). In this case-control study 30 healthy controls and 60 diagnosed cases of acute myocardial infarction (AMI) were enrolled. Serum copper concentration and serum lipid profile were measured in all study subjects. Serum copper level was significantly higher in AMI as compared to controls. The concentrations of serum TC, TG, LDL-C level were found to be significantly higher in cases as compared to controls. The concentration serum HDL-C was found to be significantly lower in cases as compared to controls. CAD leads to raised serum copper level and it has positive correlation with TC, TG and LDL-C but negative correlation with HDL-C in males.Keywords: Coronary artery disease; serum copper; acute myocardial infarction; total cholesterol; triglyceride; low density lipoprotein cholesterol. DOI: 10.3329/bjpp.v24i1.5730Bangladesh J Physiol Pharmacol 2008; 24(1&2) : 7-9


2018 ◽  
Vol 24 (1) ◽  
pp. 22-28
Author(s):  
Kristaps Erglis ◽  
Iveta Mintale ◽  
Ieva Briede ◽  
Aldis Rozenbergs ◽  
Sanda Jegere ◽  
...  

Abstract Objective: To evaluate the impact of two original compositions of polyphenols-containing dietary supplement on lipid profile and level of C-reactive protein (CRP) in patients with angiographycally verified coronary artery disease (CAD). Design and methods: 167 patients were selected during their scheduled post-event elective bicycle stress-test examination. All patients received standard CAD therapy and permanent statin therapy and had elevated total cholesterol (TC > 5.0 mmol/L) and/or CRP (>3.5 mg/L) levels. The study consisted of 2 days of polyphenol depletion followed by a 12-week supplementation period in a randomized, blinded, placebo-uncontrolled parallel design. Two different compositions SILVA 1 (Quercetine, linseed oil and Resveratrol), and SILVA 2 (Quercetine, linseed oil and Pycnogenol) were tested. Results: All parameters changed compared baseline and 1 and 3 months in both groups. CRP decreased from 2.48 ± 1.62 mg/L at baseline to 1.97 ± 1.15 mg/L, high density cholesterol (HDL-C) increased from 1.18 ± 0.31 to 1.38 ± 0.34 mmol/L, also decrease of triglycerides (TG) from 1.5 to 1.29 mmol/L after 3 months treatment in SILVA I group was statistically significant (p < 0.001). Changes of parameters between baseline and 1 or 3 months in SILVA II group were not statistically significant. Hovewer, decrease of CRP (from 2.6 ± 1.28 to 2.41 ± 1.68), decrease of low density cholesterol (LDL-C from 2.95 ± 1.2 to 2.88 ± 1.21), increase of HDL-C (from 1.25 ± 0.22 to 1.34 ± 0.23), decrease of TC (from 5.2 ± 1.3 to 5.1 ± 1.28) and decrease of TG (from 1.4 ± 0.41 to 1.3 ± 0.38) can be counted as tendency of changes. Conclusion: This study reveals the superiority of treatment with statins in combination with composition containing Resveratrol for correction of lipid profile and inflamation marker CRP of patients with CAD


Author(s):  
Vivek Verma ◽  
Ashwani Kumar Mishra ◽  
Anita Verma ◽  
Hafiz T.A. Khan ◽  
Dilip C. Nath ◽  
...  

2014 ◽  
Vol 04 (02) ◽  
pp. 094-097
Author(s):  
Deepti G. I. ◽  
Sukanya Shetty ◽  
Ashalatha V. Rao ◽  
Sarfraz Ahmad

Abstract: Background and objectives: Lipid disorder is a major risk factor for the progression of coronary artery disease. Age alone is a significant predictor of CVD risk in men and women. Before menopause, women have a much lower risk for cardiovascular events compared with men of their age. Reasons for protection from CVD in premenopausal women are complex, but a significant contribution can be assigned to the greater high-density lipoprotein (HDL) levels in younger women, which is an effect of estrogen. Methods: Fasting blood samples were collected from 40 healthy individuals (40 females divided into 2 groups according to age). Serum total cholesterol, triglycerides, and HDL- Cholesterol were estimated by enzymatic methods and LDL was calculated by Friedewald's equation. Results: The result showed increase in jyounger age group. Conclusion: It can be concluded that serum lipid profile changes can possibly be mediated by changing hormonal profile, especially estrogen which has role in lipid metabolism and indirectly on coronary artery disease.


Sign in / Sign up

Export Citation Format

Share Document