Folic acid in pregnant women associated with reduced prevalence of severe congenital heart defects in their children: a national population-based case–control study

Author(s):  
Andrew E. Czeizel ◽  
Attila Vereczkey ◽  
István Szabó
1999 ◽  
Vol 149 (8) ◽  
pp. 717-725 ◽  
Author(s):  
R. S. Boneva ◽  
C. A. Moore ◽  
L. Botto ◽  
L.-Y. Wong ◽  
J. David Erickson

2017 ◽  
Vol 173 (5) ◽  
pp. 1231-1236
Author(s):  
Martina A. Steurer ◽  
Mary E. Norton ◽  
Rebecca J. Baer ◽  
Gary M. Shaw ◽  
Sheila Keating ◽  
...  

Author(s):  
Marian K. Bakker ◽  
Wilhelmina S. Kerstjens-Frederikse ◽  
Charles H. C. M. Buys ◽  
Hermien E. K. de Walle ◽  
Lolkje T. W. de Jong-van den Berg

Author(s):  
Jiaomei Yang ◽  
Yijun Kang ◽  
Yue Cheng ◽  
Lingxia Zeng ◽  
Hong Yan ◽  
...  

Limited studies investigating the relationships between dietary patterns and congenital heart defects (CHDs) are available. This study aimed to explore the associations between dietary patterns and CHDs risk in Shaanxi, China. We conducted a hospital-based case-control study and included a total of 474 cases and 948 controls. Pregnant women waiting for delivery in the hospital were interviewed to report their diets during pregnancy using a validated food frequency questionnaire. Dietary patterns were derived using principal component factor analysis. Mixed logistic regression models were used to assess the associations between dietary patterns and CHDs. Pregnant women in the highest tertile of the prudent pattern had a lower risk of CHDs compared to those in the lowest tertile (OR = 0.65, 95%CI: 0.48–0.89). Pregnant women with high scores on the vegetarian pattern were at an increased risk of CHDs (medium vs. lowest tertile: OR = 1.50, 95%CI = 1.03–2.17; highest vs. lowest tertile: OR = 1.56, 95%CI = 1.13–2.15; ptrend = 0.015). Pregnant women with high scores on the dairy and egg pattern were at a reduced risk of CHDs (medium vs. lowest tertile: OR = 0.66, 95%CI = 0.49–0.90; highest vs. lowest tertile: OR = 0.60, 95%CI = 0.43–0.82; ptrend = 0.001). Maternal diet during pregnancy is an important target for intervention, and it may influence the likelihood of developing CHDs.


Sign in / Sign up

Export Citation Format

Share Document