The impact of copper impregnated wound dressings on surgical site infection following caesarean section: a double blind randomised controlled study

Surgical site infection (SSI) following caesarean section is associated with increased morbidity, mortality, and significant health care costs. This study evaluated the epidemiological, clinical, and microbiological features of Acinetobacter spp. in women with SSIs who have undergone caesarean section at a referral hospital in the Brazilian Amazon region. This study included 69 women with post-caesarean SSI by Acinetobacter spp. admitted to the hospital between January 2012 and May 2015. The 69 Acinetobacter isolates were subjected to molecular species identification, antimicrobial susceptibility testing, detection of carbapenemase-encoding genes, and genotyping. The main complications of post-caesarean SSI by Acinetobacter were inadequate and prolonged antibiotic therapy, sepsis, prolonged hospitalization, and re-suture procedures. A. baumannii, A. nosocomialis and A. colistiniresistens species were identified among the isolates. Carbapenem resistance was associated with OXA-23-producing A. baumannii isolates and IMP-1-producing A. nosocomialis isolate. Patients with multidrug-resistant A. baumannii infection showed worse clinical courses. Dissemination of persistent epidemic clones was observed, and the main clonal complexes (CC) for A. baumannii were CC231 and CC236 (Oxford scheme) and CC1 and CC15 (Pasteur scheme). This is the first report of a long-term Acinetobacter spp. outbreak in women who underwent caesarean section at a Brazilian hospital. This study demonstrates the impact of multidrug resistance on the clinical course of post-caesarean infections.

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Acupuncture for the induction of labour: a double-blind randomised controlled study

BJOG An International Journal of Obstetrics & Gynaecology ◽

10.1111/j.1471-0528.2010.02804.x ◽

2011 ◽

Vol 118 (3) ◽

pp. 377-377

Author(s):

P Steer

Keyword(s):

Induction Of Labour ◽

Controlled Study ◽

Double Blind ◽

Randomised Controlled Study ◽

Randomised Controlled

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The effect of high dose antibiotic impregnated cement on rate of surgical site infection after hip hemiarthroplasty for fractured neck of femur: a protocol for a double-blind quasi randomised controlled trial

BMC Musculoskeletal Disorders ◽

10.1186/1471-2474-14-356 ◽

2013 ◽

Vol 14 (1) ◽

Cited By ~ 7

Author(s):

Andrew P Sprowson ◽

Cyrus D Jensen ◽

Sanjay Gupta ◽

Nick Parsons ◽

Aradhyula N Murty ◽

...

Keyword(s):

Randomised Controlled Trial ◽

Surgical Site Infection ◽

Controlled Trial ◽

High Dose ◽

Site Infection ◽

Fractured Neck Of Femur ◽

Double Blind ◽

Neck Of Femur ◽

Hip Hemiarthroplasty ◽

Randomised Controlled

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Neonatal outcomes following phenylephrine or norepinephrine for treatment of spinal anaesthesia-induced hypotension at emergency caesarean section in women with fetal compromise – a randomised controlled study

International Journal of Obstetric Anesthesia ◽

10.1016/j.ijoa.2021.103247 ◽

2021 ◽

pp. 103247

Author(s):

M. Mohta ◽

N. Bambode ◽

G.T. Chilkoti ◽

R. Agarwal ◽

R.K. Malhotra ◽

...

Keyword(s):

Caesarean Section ◽

Spinal Anaesthesia ◽

Emergency Caesarean Section ◽

Neonatal Outcomes ◽

Controlled Study ◽

Induced Hypotension ◽

Emergency Caesarean ◽

Randomised Controlled Study ◽

Randomised Controlled ◽

Fetal Compromise

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Continuous bilateral thoracic paravertebral blockade for analgesia after cardiac surgery: a randomised, controlled trial

Perfusion ◽

10.1177/0267659117715507 ◽

2017 ◽

Vol 32 (7) ◽

pp. 591-597 ◽

Cited By ~ 5

Author(s):

Geoff G. Lockwood ◽

Leilani Cabreros ◽

Dorota Banach ◽

Prakash P. Punjabi

Keyword(s):

Cardiac Surgery ◽

Primary Outcome ◽

Controlled Trial ◽

Morphine Consumption ◽

Controlled Study ◽

Double Blind ◽

Clinical Trial Registration ◽

Subcutaneous Infusion ◽

Randomised Controlled Study ◽

Randomised Controlled

Background: Continuous bilateral thoracic paravertebral blockade has been used for analgesia after cardiac surgery, but its efficacy has never been formally tested. Method: Fifty adult patients were enrolled in a double-blind, randomised, controlled study of continuous bilateral thoracic paravertebral infusion of 0.5% lidocaine (1 mg.kg-1.hr-1) for analgesia after coronary surgery. Control patients received a subcutaneous infusion of lidocaine at the same rate through catheters inserted at the same locations as the study group. The primary outcome was morphine consumption at 48 hours using patient-controlled analgesia (PCA). Secondary outcomes included pain, respiratory function, nausea and vomiting. Serum lidocaine concentrations were measured on the first two post-operative days. Results: There was no difference in morphine consumption or in any other outcome measure between the groups. Serum lidocaine concentrations increased during the study, with a maximum of 5.9 mg.l-1. There were no adverse events as a consequence of the study. Conclusion: Bilateral paravertebral infusion of lidocaine confers no advantage over systemic lidocaine infusion after cardiac surgery. Clinical trial registration: ISRCTN13424423 ( https://www.isrctn.com )

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