Physical activity, fatigue and sleep quality at least 6 months after mild traumatic brain injury in adolescents and young adults: A comparison with orthopedic injury controls

2019 ◽  
Vol 23 (5) ◽  
pp. 707-715 ◽  
Author(s):  
Frederike van Markus-Doornbosch ◽  
Els Peeters ◽  
Gerard Volker ◽  
Stéphanie van der Pas ◽  
Thea Vliet Vlieland ◽  
...  
2015 ◽  
Vol 28 (2) ◽  
pp. 53-62 ◽  
Author(s):  
Adam T. Schmidt ◽  
Xiaoqi Li ◽  
Gerri R. Hanten ◽  
Stephen R. McCauley ◽  
Jessica Faber ◽  
...  

2019 ◽  
Vol 23 (1) ◽  
pp. 53-60 ◽  
Author(s):  
F. van Markus-Doornbosch ◽  
E. Peeters ◽  
S. van der Pas ◽  
T. Vliet Vlieland ◽  
J. Meesters

Biomedicines ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 36
Author(s):  
Rany Vorn ◽  
Maiko Suarez ◽  
Jacob C. White ◽  
Carina A. Martin ◽  
Hyung-Suk Kim ◽  
...  

Chronic mild traumatic brain injury (mTBI) has long-term consequences, such as neurological disability, but its pathophysiological mechanism is unknown. Exosomal microRNAs (exomiRNAs) may be important mediators of molecular and cellular changes involved in persistent symptoms after mTBI. We profiled exosomal microRNAs (exomiRNAs) in plasma from young adults with or without a chronic mTBI to decipher the underlying mechanisms of its long-lasting symptoms after mTBI. We identified 25 significantly dysregulated exomiRNAs in the chronic mTBI group (n = 29, with 4.48 mean years since the last injury) compared to controls (n = 11). These miRNAs are associated with pathways of neurological disease, organismal injury and abnormalities, and psychological disease. Dysregulation of these plasma exomiRNAs in chronic mTBI may indicate that neuronal inflammation can last long after the injury and result in enduring and persistent post-injury symptoms. These findings are useful for diagnosing and treating chronic mTBIs.


2017 ◽  
Vol 65 (4) ◽  
pp. 761 ◽  
Author(s):  
DhavalP Shukla ◽  
Subir Dey ◽  
Jagathlal Gangadharan ◽  
Akhil Deepika ◽  
JKeshav Kumar ◽  
...  

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