Serum levels of catecholamine metabolites and return to work in patients with major depression: a preliminary study

2021 ◽  
Author(s):  
Reiji Yoshimura ◽  
Naomichi Okamoto ◽  
Yuki Konishi ◽  
Atsuko Ikenouchi
Keyword(s):  
Major Depression ◽  
Return To Work ◽  
Serum Levels ◽  
Catecholamine Metabolites ◽  
Preliminary Study

scholarly journals Amino Acid and Acylcarnitine Levels in Chronic Patients with Schizophrenia: A Preliminary Study

Metabolites ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 34
Author(s):  
Irina A. Mednova ◽  
Alexander A. Chernonosov ◽  
Marat F. Kasakin ◽  
Elena G. Kornetova ◽  
Arkadiy V. Semke ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Amino Acids ◽  
Amino Acid ◽  
Chronic Schizophrenia ◽  
Integrated Approach ◽  
Serum Levels ◽  
Tandem Mass ◽  
Chronic Patients ◽  
Healthy Donors ◽  
Preliminary Study

Amino acids and acylcarnitines play an important role as substrates and intermediate products in most of pathways involved in schizophrenia development such as mitochondrial dysfunction, inflammation, lipid oxidation, DNA damage, oxidative stress, and apoptosis. It seems relevant to use an integrated approach with ‘omics’ technology to study their contribution. The aim of our study was to investigate serum amino acid and acylcarnitine levels in antipsychotics-treated patients with chronic schizophrenia compared with healthy donors. We measured serum levels of 15 amino acids and 30 acylcarnitines in 37 patients with schizophrenia and 36 healthy donors by means of tandem mass spectrometry. In summary, patients with chronic schizophrenia had an altered concentration of a few amino acids and acylcarnitines in comparison to the healthy probands. Further research is needed to assess and understand the identified changes.

Altered White Matter Microstructure in Adolescents With Major Depression: A Preliminary Study

2010 ◽  
Vol 49 (2) ◽  
pp. 173-183.e1 ◽  
Author(s):  
Kathryn R. Cullen ◽  
Bonnie Klimes-Dougan ◽  
Ryan Muetzel ◽  
Bryon A. Mueller ◽  
Jazmin Camchong ◽  
...  
Keyword(s):  
White Matter ◽  
Major Depression ◽  
White Matter Microstructure ◽  
Preliminary Study

Social cognition and interaction training for major depression: A preliminary study

2018 ◽  
Vol 270 ◽  
pp. 890-894 ◽  
Author(s):  
Sheng Zhu ◽  
Kai Zhu ◽  
Deguo Jiang ◽  
Jianfei Shi
Keyword(s):  
Social Cognition ◽  
Major Depression ◽  
Preliminary Study

scholarly journals MMP-7 and fcDNA Serum Levels in Early NSCLC and Idiopathic Interstitial Pneumonia: Preliminary Study

2013 ◽  
Vol 14 (12) ◽  
pp. 24097-24112 ◽  
Author(s):  
Paola Ulivi ◽  
Gian Casoni ◽  
Giovanni Foschi ◽  
Emanuela Scarpi ◽  
Sara Tomassetti ◽  
...  
Keyword(s):  
Interstitial Pneumonia ◽  
Serum Levels ◽  
Idiopathic Interstitial Pneumonia ◽  
Preliminary Study

Serum. Levels of Dihydroneopterin and Soluble Cytokine Receptors in Major Depression

Pteridines ◽  
1999 ◽  
Vol 10 (1) ◽  
pp. 24-26
Author(s):  
Kazunori Kusunoki ◽  
Norio Ozaki ◽  
Makoto Sawada ◽  
Tetsuya Sato ◽  
Shigeki Hirano ◽  
...  
Keyword(s):  
Major Depression ◽  
Drug Treatment ◽  
Tumor Necrosis Factor Receptor ◽  
Serum Levels ◽  
Type I ◽  
Type Ii ◽  
Before And After ◽  
Interleukin 6 Receptor ◽  
And Gender ◽  
Necrosis Factor

The serum levels of dihydroneopterin (NH2), soluble interleukin -6 receptor (sIL-6R), soluble tumor necrosis factor receptor (sTNF-R) type I and type II were measured in 18 patients with major depression before and after drug treatment and in age- and gender-matched healthy controls. The NH2 and sTNF-R type II levels were significantly higher both in untreated and treated patients when compared to the controls. The sTNF-R type I levels were significantly lower in untreated depressed patients than the controls and significantly increased after drug treatment when compared to those prior to treatment.

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