Clinical management of adolescents and young adults suffering from sarcoma in the French Rhône-Alpes region: A prospective exhaustive cohort with 10 years follow up

2020 ◽  
Vol 46 (7) ◽  
pp. 1301-1309 ◽  
Author(s):  
P. Marec-Bérard ◽  
S. Aho ◽  
C. Berger ◽  
D. Plantaz ◽  
L.S. Aho-Glelé ◽  
...  
2002 ◽  
Vol 17 (6) ◽  
pp. 321-331 ◽  
Author(s):  
Roselind Lieb ◽  
Petra Zimmermann ◽  
Robert H Friis ◽  
Michael Höfler ◽  
Sven Tholen ◽  
...  

SummaryObjective.Although somatoform disorders are assumed to be chronic clinical conditions, epidemiological knowledge on their natural course based on representative samples is not available.Method.Data come from a prospective epidemiologic study of adolescents and young adults in Munich, Germany. Respondents’ diagnoses (N = 2548) at baseline and follow-up on average 42 months later are considered. The follow-up incidence, stability as well as selected baseline risk factors (sociodemographics, psychopathology, trauma exposure) for the incidence and stability of somatoform disorders and syndromes are prospectively examined. Diagnostic information was assessed by using the standardized Munich-Composite International Diagnostic Interview (M-CIDI).Results.Over the follow-up period, incidence rate for any of the covered somatoform diagnoses was 25.7%. Stability for the overall group of any somatoform disorder/syndrome was 48%. Female gender, lower social class, the experience of any substance use, anxiety and affective disorder as well as the experience of traumatic sexual and physical threat events predicted new onsets of somatoform conditions, while stability was predicted by being female, prior existing substance use, affective and eating disorders as well as the experience of a serious accident.Conclusions.At least for a substantial proportion of individuals, the overall picture of somatization seems to be relatively stable, but with fluctuation in the symptom picture over time. Being female, the experience of substance use as well as anxiety disorder seem to constitute risk factors for the onset of new somatoform conditions as well as for a stable course over time.


2018 ◽  
Vol 7 (12) ◽  
pp. 543 ◽  
Author(s):  
Sarvenaz Esmaeelzadeh ◽  
John Moraros ◽  
Lilian Thorpe ◽  
Yelena Bird

Background: The purpose of this systematic review was to examine the association and directionality between mental health disorders and substance use among adolescents and young adults in the U.S. and Canada. Methods: The following databases were used: Medline, PubMed, Embase, PsycINFO, and Cochrane Library. Meta-analysis used odds ratios as the pooled measure of effect. Results: A total of 3656 studies were screened and 36 were selected. Pooled results showed a positive association between depression and use of alcohol (odds ratio (OR) = 1.50, 95% confidence interval (CI): 1.24–1.83), cannabis (OR = 1.29, 95% CI: 1.10–1.51), and tobacco (OR = 1.65, 95% CI: 1.43–1.92). Significant associations were also found between anxiety and use of alcohol (OR = 1.54, 95% CI: 1.19–2.00), cannabis (OR = 1.36, 95% CI: 1.02–1.81), and tobacco (OR = 2.21, 95% CI: 1.54–3.17). A bidirectional relationship was observed with tobacco use at baseline leading to depression at follow-up (OR = 1.87, CI = 1.23–2.85) and depression at baseline leading to tobacco use at follow-up (OR = 1.22, CI = 1.09–1.37). A unidirectional relationship was also observed with cannabis use leading to depression (OR = 1.33, CI = 1.19–1.49). Conclusion: This study offers insights into the association and directionality between mental health disorders and substance use among adolescents and young adults. Our findings can help guide key stakeholders in making recommendations for interventions, policy and programming.


Author(s):  
Laurel Elise Money ◽  
Ishara Ramkissoon

Background: Recent research indicated that young adults and adolescents reported tinnitus in highernumbers than previously. Thus, it is important to fully investigate risk factors for tinnitus in adolescentsand young adults.<br />Purpose: The current study examined the influence of two environmental risk factors, secondhandsmoke (SHS) exposure and noise exposure on tinnitus occurrence as self-reported by U.S. adolescentsand young adults.<br />Research Design: A nonexperimental, cross-sectional design was used for this survey study.<br />Study Sample: Of 265 surveys received, 43 were excluded due to ineligibility. The remaining 222 surveysconstituted the study sample. Participant respondents included 80 high school students (ages14–17) and 142 college students (ages 18–30). The sample was primarily female (n = 160).<br />Data Collection and Analysis: Three (3) yes/no survey questions regarding SHS exposure, noise exposure,and tinnitus occurrence were analyzed. Statistical analyses included logistic regression, chisquarefollow-up tests, and Pearson bivariate correlation analysis.<br />Results: Results revealed that 40 percent of young adults and adolescents surveyed reported that they experiencedtinnitus. Regression analysis revealed significant main effects for noise (p = 0.004), gender (p =0.017), and the interaction of SHS and noise (p = 0.001). There was no main effect of SHS exposurenor age on tinnitus occurrence. Follow-up chi-square analysis conducted to probe the gender effectrevealed that females (45.1 percent) were more likely to experience tinnitus than males (27.7 percent). Chi-squaretesting to examine the significant interaction effect revealed statistical significance (p = 0.001) for individualswith reported noise exposure but not for individuals without noise exposure. In the noise-exposedgroup, individuals who also reported SHS exposure had a lower occurrence of tinnitus (23.6 percent). In contrast,the noise-exposed individuals without SHS exposure had a higher prevalence of tinnitus (57.9 percent).An additional chi-square follow-up analysis to examine the main effect of noise revealed no significance(p = 0.199). However, there was a significant (p < 0.01) negative correlation (r = –0.244) of noise exposurewith age.<br />Conclusion: The current study results suggest there is a higher than expected report of tinnitus incidencein adolescents and young adults. The relationship between tinnitus occurrence and a combinedexposure to noise and secondhand smoke revealed a unique effect in adolescents and young adults.<br />


2020 ◽  
Vol 66 (2) ◽  
pp. S36
Author(s):  
Sarah Pitts ◽  
Carly Milliren ◽  
Grace Berg ◽  
Danielle McPeak ◽  
Amy DiVasta

2020 ◽  
Vol 84 (2) ◽  
pp. 105-136
Author(s):  
Jill Ehrenreich-May ◽  
Gregory Simpson ◽  
Lindsay M. Stewart ◽  
Sarah M. Kennedy ◽  
Amelia N. Rowley ◽  
...  

Anxiety disorders are commonly comorbid in adolescents and young adults with high-functioning autism. Cognitive-behavioral treatments (CBT) for anxiety, when adapted and expanded to target autism spectrum disorder (ASD) characteristics, may be beneficial, but there is minimal evidence to guide clinicians in their application. This multiple-baseline design study evaluated the initial efficacy of a CBT protocol adapted to address anxiety symptoms and adaptive functioning in this population. Anxiety and ASD symptoms were assessed for six participants at intake, after baseline, posttreatment, and at 1-month follow-up. Parent- and child-reported anxiety was also assessed during baseline and treatment. Visual inspection and reliable change index scores were used to evaluate change. All participants improved on clinician-rated measures of disorder severity, and gains were maintained at follow-up. Results were more equivocal for parent- and self-rated anxiety and parent-rated ASD, partly because of spontaneous changes during baseline.


PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0210937 ◽  
Author(s):  
Pancho Mulongeni ◽  
Sabine Hermans ◽  
Judy Caldwell ◽  
Linda-Gail Bekker ◽  
Robin Wood ◽  
...  

2018 ◽  
Vol 64 ◽  
pp. 108-113 ◽  
Author(s):  
Marianna Romei ◽  
Laura M. Oudenhoven ◽  
Petra E.M. van Schie ◽  
Willem J.R. van Ouwerkerk ◽  
Marjolein M. van der Krogt ◽  
...  

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