Significance of Partial or Complete Thrombosis of the Common and Deep Femoral Vein in Patients With Deep Vein Thrombosis

Background Breast reconstruction is associated with multiple risk factors for venous thromboembolism. However, the incidence of deep vein thrombosis in patients undergoing breast reconstruction is uncertain. Objective The aim of this study was to prospectively evaluate the incidence of deep vein thrombosis in patients undergoing breast reconstruction using autologous tissue transfer and to identify potential risk factors for deep vein thrombosis. Methods Thirty-five patients undergoing breast reconstruction were enrolled. We measured patients’ preoperative characteristics including age, body mass index (kg/m2), and risk factors for deep vein thrombosis. The preoperative diameter of each venous segment in the deep veins was measured using duplex ultrasound. All patients received intermittent pneumatic pump and elastic compression stockings for postoperative thromboprophylaxis. Results Among the 35 patients evaluated, 11 (31.4%) were found to have deep vein thrombosis postoperatively, and one patient was found to have pulmonary embolism postoperatively. All instances of deep vein thrombosis developed in the calf and were asymptomatic. Ten of 11 patients underwent free flap transfer, and the remaining one patient received a latissimus dorsi pedicled flap. Deep vein thrombosis incidence did not significantly differ between patients with a free flap or pedicled flap (P = 0.13). Documented risk factors for deep vein thrombosis demonstrated no significant differences between patients with and without deep vein thrombosis. The diameter of the common femoral vein was significantly larger in patients who developed postoperative deep vein thrombosis than in those who did not ( P < 0.05). Conclusions The morbidity of deep vein thrombosis in patients who underwent breast reconstruction using autologous tissue transfer was relatively high. Since only the diameter of the common femoral vein was predictive of developing postoperative deep vein thrombosis, postoperative pharmacological thromboprophylaxis should be considered for all patients undergoing breast reconstruction regardless of operative procedure.

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Feasibility of identifying deep vein thrombosis characteristics with contrast enhanced MR-Venography

Phlebology The Journal of Venous Disease ◽

10.1177/0268355514529697 ◽

2014 ◽

Vol 29 (1_suppl) ◽

pp. 119-124 ◽

Cited By ~ 11

Author(s):

CWKP Arnoldussen ◽

RHW Strijkers ◽

DMJ Lambregts ◽

MJ Lahaye ◽

R de Graaf ◽

...

Keyword(s):

Deep Vein Thrombosis ◽

Interobserver Agreement ◽

Average Duration ◽

Femoral Vein ◽

Mr Venography ◽

Common Femoral Vein ◽

Vein Thrombosis ◽

Contrast Enhanced ◽

The Common ◽

Deep Vein

Purpose To assess the feasibility of identifying deep vein thrombosis characteristics with contrast enhanced magnetic resonance venography. Materials and Methods A total of 53 cases of deep vein thrombosis extending in and/or above the common femoral vein were evaluated by 4 independent observers (2 expert, 2 novice) using pre-determined characteristics to determine the thrombosis present to be acute, sub-acute or old. If present, chronic remnants of a previous deep vein thrombosis were reported. Additionally these image qualifications were compared to the reported duration of complaints. Results In all cases all observers were able to qualify the thrombosis. The interobserver agreement between the experts was excellent (kappa 0.97) and good between expert and novice (kappa 0.82). Thrombosis identified as acute had an average duration of complaints of 6,5 (2–13) days, sub‐acute 13 (8–18) days and old 22 (15–32) days. Conclusion Qualification of thrombosis as acute, sub-acute or old and identification of chronic remnants of DVT with CE-MRV using routinely identifiable characteristics is feasible and reproducible with good to excellent interobserver agreement.

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Adventitial cystic disease of the common femoral vein presenting as deep vein thrombosis

Asian Journal of Surgery ◽

10.1016/j.asjsur.2013.07.002 ◽

2016 ◽

Vol 39 (3) ◽

pp. 178-181 ◽

Cited By ~ 5

Author(s):

Young-Kyun Kim ◽

Ho Jong Chun ◽

Jeong Kye Hwang ◽

Ji Il Kim ◽

Sang Dong Kim ◽

...

Keyword(s):

Deep Vein Thrombosis ◽

Femoral Vein ◽

Cystic Disease ◽

Common Femoral Vein ◽

Vein Thrombosis ◽

Adventitial Cystic Disease ◽

The Common ◽

Deep Vein

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Chronic lower extremity deep vein thrombosis associated with femoral vein compression by a lipoma.

American Journal of Roentgenology ◽

10.2214/ajr.172.6.10350325 ◽

1999 ◽

Vol 172 (6) ◽

pp. 1697-1698 ◽

Cited By ~ 5

Author(s):

P S Brady ◽

L D Spence

Keyword(s):

Deep Vein Thrombosis ◽

Lower Extremity ◽

Femoral Vein ◽

Vein Thrombosis ◽

Deep Vein

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A murine model of deep vein thrombosis Characterization and validation in transgenic mice

Thrombosis and Haemostasis ◽

10.1160/th05-03-0170 ◽

2005 ◽

Vol 94 (09) ◽

pp. 498-503 ◽

Cited By ~ 25

Author(s):

Linda Szema ◽

Chao-Ying Chen ◽

Jeffrey P. Schwab ◽

Gregory Schmeling ◽

Brian C. Cooley

Keyword(s):

Deep Vein Thrombosis ◽

Murine Model ◽

Femoral Vein ◽

Previous History ◽

Bed Rest ◽

Major Surgery ◽

Vein Thrombosis ◽

Transgenic Lines ◽

History Of ◽

Deep Vein

SummaryDeep vein thrombosis (DVT) occurs with high prevalence in association with a number of risk factors, including major surgery, trauma, obesity, bed rest (>5 days), cancer, a previous history of DVT, and several predisposing prothrombotic mutations. A novel murine model of DVT was developed for applications to preclinical studies of transgenically constructed prothrombotic lines and evaluation of new antithrombotic therapies. A transient direct-current electrical injury was induced in the common femoral vein of adult C57Bl/6 mice. A non-occlusive thrombus grew, peaking in size at 30 min, and regressing by 60 min, as revealed by histomorphometric volume reconstruction of the clot. Pre-heparinization greatly reduced clot formation at 10, 30, and 60 min (p<0.01 versus non-heparinized). Homozygous FactorV Leiden mice (analogous to the clinical FactorV Leiden prothrombotic mutation) on a C57Bl/6 background had clot volumes more than twice those of wild-types at 30 min (0.121±0.018 mm3 vs. 0.052±0.008 mm3, respectively; p<0.01). Scanning electron microscopy revealed a clot surface dominated by fibrin strands, in contrast to arterial thrombi which showed a platelet-dominated structure. This new model of DVT presents a quantifiable approach for evaluating thrombosis-related murine transgenic lines and for comparatively evaluating new pharmacologic approaches for prevention of DVT.

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TCTAP C-223 Catheter-directed Thrombolysis, Iliac and Common Femoral Vein Stenting in May-thurner Syndrome with Refractory Deep Vein Thrombosis

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2016.03.438 ◽

2016 ◽

Vol 67 (16) ◽

pp. S373-S374

Author(s):

Chiung-Ray Lu ◽

Ke Wei Chen

Keyword(s):

Deep Vein Thrombosis ◽

Femoral Vein ◽

Common Femoral Vein ◽

Vein Thrombosis ◽

Catheter Directed Thrombolysis ◽

Deep Vein

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Advantages of a Sequential Compression Device in Prevention of Deep Vein Thrombosis

10.1055/s-0039-1684785 ◽

1979 ◽

Author(s):

A.N. Nicolaides ◽

J. Fernandas ◽

A.V. Pollock

Keyword(s):

Deep Vein Thrombosis ◽

Femoral Vein ◽

Test Group ◽

Heparin Group ◽

Similar Time ◽

Vein Thrombosis ◽

Compression Device ◽

Fibrinogen Test ◽

Group B ◽

Deep Vein

A sequential compression device (SCD) (6 chambers) compressing the ankle, calf end thigh sequentially at 35, 30 and 20 mm Hg for 12 seconds in every minute produced a 240% increase in peak velocity in the femoral vein. A non-sequential device (NSD) inflated to 25 mm Hg with a similar time cycle produced only an 180% increase in blood velocity.The two devices were tested clinically; 250 surgical patients were randomised to 3 groups scanned with the 125 I-fibrinogen test. Group A: 7 days subcutaneous heparin. Group B: NSD for 24 hours. Group C: SCD for 24 hours. The SCD was found to be as effective as heparin during the period it was used and more effective than NSD in preventing deep vein thrombosis proximal to the calf.

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