scholarly journals Staged Pharmacological and Surgical Treatment of Pulmonary Embolism and Paradoxical Embolism in Patient With Acute Deep Vein Thrombosis of the Lower Extremity

2019 ◽  
Vol 58 (6) ◽  
pp. e731
Author(s):  
Temirlan Gamzatov ◽  
Aleksei Kebriakov ◽  
Aleksei Svetlikov

Author(s):  
Carlo Setacci ◽  
Marco Tadiello ◽  
Francesco Setacci ◽  
Gianmarco De Donato ◽  
Matteo Tozzi ◽  
...  


2017 ◽  
Author(s):  
Guillermo A. Escobar ◽  
Peter K. Henke ◽  
Thomas W. Wakefield

Deep vein thrombosis (DVT) and pulmonary embolism (PE) comprise venous thromboembolism (VTE). Together, they comprise a serious health problem as there are over 275,000 new VTE cases per year in the United States, resulting in a prevalence of one to two per 1,000 individuals, with some studies suggesting that the incidence may even be double that. This review covers assessment of a VTE event, initial evaluation of a patient suspected of having VTE, medical history, clinical presentation of VTE, physical examination, laboratory evaluation, imaging, prophylaxis against perioperative VTE, indications for immediate intervention (threat to life or limb), indications for urgent intervention, and management of nonemergent VTE. Figures show a modified Caprini score questionnaire used at the University of Michigan to determine individual risk of VTE and the indicated prophylaxis regimen; Wells criteria for DVT and PE; phlegmasia cerulea dolens secondary to acute left iliofemoral DVT after thigh trauma; compression duplex ultrasonography of lower extremity veins; computed tomographic angiogram of the chest demonstrating a thrombus in the pulmonary artery, with extension into the right main pulmonary; management of PE according to Wells criteria findings; management of PE with right heart strain in cases of massive or submassive PE; treatment of DVT according to clinical scenario; a lower extremity venogram of a patient with May-Thurner syndrome and its subsequent endovascular treatment; and various examples of retrievable vena cava filters (not drawn to scale). Tables list initial clinical assessment for VTE, clinical scenarios possibly benefiting from prolonged anticoagulation after VTE, indications for laboratory investigation of secondary thrombophilia, venous thromboembolic risk accorded to hypercoagulable states, and Pulmonary Embolism Rule-out Criteria Score to avoid the need for D-dimer in patients suspected of having PE.   This review contains 11 highly rendered figures, 5 tables, and 167 references. Key words: anticoagulation; deep vein thrombosis; postthrombotic syndrome; pulmonary embolism; recurrent venous thromboembolism; thrombophilia; venous thromboembolism; PE; VTE; DVT 



2015 ◽  
Vol 28 (1) ◽  
pp. 12 ◽  
Author(s):  
Liliana Sousa Nanji ◽  
André Torres Cardoso ◽  
João Costa ◽  
António Vaz-Carneiro

<p>The standard treatment for acute deep vein thrombosis (DVT) targets to reduce immediate complications, however thrombolysis could reduce the long-term complications of post-thrombotic syndrome in the affected limb. This systematic review aimed to assess the effects of thrombolytic therapy and anticoagulation <em>versus </em>anticoagulation in people with deep vein thrombosis of the lower limb through the effects on pulmonary embolism, recurrent deep vein thrombosis, major bleeding, post-thrombotic complications, venous patency and venous function. The Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last search in April 2013) and CENTRAL (2013, Issue 4). A total of 17 randomised controlled trials (RCTs) and 1103 participants were included. In the experimental group receiving thrombolysis, complete clot lysis occurred more frequently and there was greater improvement in venous patency. The incidence of post-thrombotic syndrome decreased by a 1/3 and venous ulcers were less frequent. There were more bleeding complications and 3 strokes occurred in less recent studies, yet there seemed to be no significant effect on mortality. Data on the occurrence of pulmonary embolism and recurrent deep vein thrombosis were inconclusive. There are advantages to thrombolysis, yet the application of rigorous criteria is warranted to reduce bleeding complications. Catheter-directed thrombolysis is the current preferred method, as opposed to systemic thrombolysis in the past, and other studies comparing these procedures show that results are similar.</p><p><strong>Keywords:</strong> Randomized Controlled Trials as Topic; Thrombolytic Therapy; Venous Thrombosis.</p>



CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 409A ◽  
Author(s):  
Mashio Nakamura ◽  
Yoshiaki Okano ◽  
Hiroki Minamigichi ◽  
Hiroshi Tsujimoto ◽  
Hiromu Nakajima ◽  
...  


2019 ◽  
Vol 229 (4) ◽  
pp. S291
Author(s):  
Christina X. Zhang ◽  
Yun Zhu Bai ◽  
Qiao Zhang ◽  
Jennifer M. Leonard ◽  
Rohit K. Rasane ◽  
...  


1991 ◽  
Vol 5 (3) ◽  
pp. 255-260 ◽  
Author(s):  
B. van Ramshorst ◽  
D.A. Legemate ◽  
J.F. Verzijlbergen ◽  
H. Hoeneveld ◽  
B.C. Eikelboom ◽  
...  




2021 ◽  
Vol 37 ◽  
pp. 1-6
Author(s):  
Sangmin Gong ◽  
Eun Ji Lee ◽  
Jin Sung Kim ◽  
Hyangkyoung Kim ◽  
Minsu Noh ◽  
...  


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