The Comorbidity of Traumatic Life Events in Childhood Age With Adult Obsessive-Compulsive Disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S497-S497 ◽  
Author(s):  
S. Kıvılcım ◽  
H. Erensoy ◽  
D.B. Tonguç ◽  
G. Sarıdogan ◽  
K. Ebru
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Life Events ◽  
Emotional Abuse ◽  
Epidemiological Studies ◽  
Healthy Population ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Traumatic Life Events ◽  
Statistical Level

PurposeObsessive-Compulsive Disorder (OCD) is a mental disorder characterized by obsessions and/or compulsions. Although some epidemiological studies take part in literature, which claim that traumatic life events in childhood ages are observed more in patients with OCD compared to healthy population, the number of these studies is limited. In this study, it is aimed to compare OCD patients with healthy volunteers in terms of traumatic life events in childhood ages.MethodWith 25 consecutive patients who are diagnosed as OCD and whose treatment continues, 25 healthy controls equivalent in terms of sociodemographic features are included in the study. Sociodemographic Data Form, Childhood Age Trauma Quarter (CTQ) and Maudley Obsessive Compulsive Question List (MOCQL) are applied to the participants. Significance Value in statistical level is accepted as P < 0.05.FindingsIn OCD patient group, CTQ scores are found high in statistical level compared to healthy controls. It has been determined that there is a significant relationship between total score of MOCQL slowness subscale scores, subscale scores of sexual and emotional abuse, MOCQL rumination subscale scores and CTQ sexual abuse scores.ResultCompared to healthy controls, more findings of traumatic life event in childhood age are observed within OCD patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Role of stressful and traumatic life events in obsessive–compulsive disorder

2011 ◽  
Vol 1 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Leonardo F Fontenelle ◽  
Luca Cocchi ◽  
Ben J Harrison ◽  
Euripedes C Miguel ◽  
Albina R Torres
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Life Events ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Traumatic Life Events

Parental emotional warmth interacts with traumatic life events in predicting the onset of obsessive-compulsive disorder

2020 ◽  
Vol 26 ◽  
pp. 100531
Author(s):  
Patrizia D. Hofer ◽  
Karina Wahl ◽  
Andrea H. Meyer ◽  
Marcel Miché ◽  
Katja Beesdo-Baum ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Life Events ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Traumatic Life Events

The inner world of overactive monitoring: neural markers of interoception in obsessive–compulsive disorder

2017 ◽  
Vol 47 (11) ◽  
pp. 1957-1970 ◽  
Author(s):  
A. Yoris ◽  
A. M. García ◽  
L. Traiber ◽  
H. Santamaría-García ◽  
M. Martorell ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Obsessive Compulsive Disorder ◽  
Evoked Potential ◽  
Cognitive Profile ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Inner World ◽  
External Stimuli ◽  
Internal Body

BackgroundObsessive–compulsive disorder (OCD) patients typically overmonitor their own behavior, as shown by symptoms of excessive doubt and checking. Although this is well established for the patients’ relationship with external stimuli in the environment, no study has explored their monitoring of internal body signals, a process known to be affected in anxiety-related syndromes. Here, we explored this issue through a cardiac interoception task that measures sensing of heartbeats. Our aim was to explore key behavioral and electrophysiological aspects of internal-cue monitoring in OCD, while examining their potential distinctiveness in this condition.MethodWe administered a heartbeat detection (HBD) task (with related interoceptive confidence and awareness measures) to three matched groups (OCD patients, panic disorder patients, healthy controls) and recorded ongoing modulations of two task-relevant electrophysiological markers: the heart evoked potential (HEP) and the motor potential (MP).ResultsBehaviorally, OCD patients outperformed controls and panic patients in the HBD task. Moreover, they exhibited greater amplitude modulation of both the HEP and the MP during cardiac interoception. However, they evinced poorer confidence and awareness of their interoceptive skills.ConclusionsConvergent behavioral and electrophysiological data showed that overactive monitoring in OCD extends to the sensing of internal bodily signals. Moreover, this pattern discriminated OCD from panic patients, suggesting a condition-distinctive alteration. Our results highlight the potential of exploring interoceptive processes in the OCD spectrum to better characterize the population's cognitive profile. Finally, these findings may lay new bridges between somatic theories of emotion and cognitive models of OCD.

EEG-source estimates and vigilance regulation in obsessive compulsive disorder in comparison to healthy controls

2011 ◽  
Vol 26 (S2) ◽  
pp. 977-977 ◽  
Author(s):  
H. Olbrich ◽  
S. Olbrich ◽  
I. Jahn ◽  
U. Hegerl ◽  
K. Stengler
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Sleep Disturbances ◽  
Imaging Techniques ◽  
Sleep Onset ◽  
Biological Marker ◽  
Multiple Comparison ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Eeg Power

Neurophysiological hyperactivation of cortical and subcortical brain areas has been reported in obsessive-compulsive disorder (OCD) using functional imaging techniques and electroencephalography (EEG). Also sleep disturbances and delayed sleep phases have been associated with OCD symptomatology. However, vigilance regulation in OCD during the transition phase from wakefulness to sleep onset remains unclear. Therefore the aim of this study was to analyze EEG-source estimates and EEG vigilance regulation in OCD patients in comparison to healthy controls.A 15 minute resting EEG was recorded in 30 unmedicated OCD patients and 30 healthy, age and gender matched controls. EEG power source estimates of the whole time series were computed by exact Low Resolution Brain Electromagnetic Tomography (eLORETA). Each consecutive one second EEG-segment was classified into one out of seven EEG-vigilance stages (0, A1, A2, A3, B1, B2/3, C) using Vigilance Algorithm Leipzig (VIGALL). The eLORETA analysis (log of F-ratios, p < 0.05, corrected for multiple comparison) revealed significantly increased delta power in the right superior frontal gyrus for OCD patients in comparison to healthy controls. Vigilance analysis yielded significantly increased amounts of high vigilance stage A2 (Mann-Whitney test, p < 0.001, corrected for multiple comparison) for OCD patients.This study repeated findings of altered EEG-power in frontal areas in OCD patients. Alterations of EEG-vigilance regulation were found with increased amounts of high vigilance stage A2. This is in line with a hypothesis of cortical hyperactivation in OCD. The value of EEG-vigilance as a possible biological marker for e.g. treatment response should be focus of further studies.

scholarly journals Executive functioning in Body Dysmorphic Disorder and Obsessive-Compulsive Disorder

2021 ◽  
Author(s):  
Long Long Chen ◽  
Oskar Flygare ◽  
John Wallert ◽  
Jesper Enander ◽  
Volen Ivanov ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Test Performance ◽  
Symptom Severity ◽  
Body Dysmorphic Disorder ◽  
Spatial Working Memory ◽  
Clinical Severity ◽  
Stop Signal Task ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Objective: To assess executive functions in patients with Body Dysmorphic Disorder (BDD) and Obsessive-Compulsive Disorder (OCD) compared with healthy controls. Methods: Adults diagnosed with BDD (n=26) or OCD (n=29) according to DSM-5, and healthy controls (n=28) underwent validated and computerized neuropsychological tests; spatial working memory (SWM), Intra- extra dimensional set shifting (IED) and Stop signal task (SST), from the Cambridge Neuropsychological Test Automated Battery (CANTAB). Test performance was compared between groups, and correlated to standardized symptom severity of BDD and OCD. Significance level was set to p<0.05. Results: There were no statistically significant between-group differences on key outcome measures in SWM, IED, or SST. There was a weak positive correlation between symptom severity and test errors on SWM and IED in both OCD and BDD groups; increased clinical severity were associated with more errors in these tests. Further, there was a negative correlation between symptom severity and SST in the BDD group. Conclusions: Patients with BDD or OCD did not differ from healthy control subjects in terms of test performance, however there were several statistically significant correlations between symptom severity and performance in those with BDD or OCD. More studies on EF in BDD and OCD are required to elucidate if there are differences in EF between these two disorders.

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