In vitro effects of docosahexaenoic and eicosapentaenoic acid on human meibomian gland epithelial cells

2015 ◽  
Vol 140 ◽  
pp. 139-148 ◽  
Author(s):  
Ulrike Hampel ◽  
Magret Krüger ◽  
Carolina Kunnen ◽  
Fabian Garreis ◽  
Mark Willcox ◽  
...  
2016 ◽  
Vol 151 ◽  
pp. 190-202 ◽  
Author(s):  
Antje Schröder ◽  
Daniel B. Abrar ◽  
Ulrike Hampel ◽  
Martin Schicht ◽  
Friedrich Paulsen ◽  
...  

2019 ◽  
Vol 222 ◽  
pp. 129-138 ◽  
Author(s):  
Anca Rath ◽  
Michael Eichhorn ◽  
Katharina Träger ◽  
Friedrich Paulsen ◽  
Ulrike Hampel

1999 ◽  
Vol 277 (1) ◽  
pp. G175-G182 ◽  
Author(s):  
Maryam Varedi ◽  
George H. Greeley ◽  
David N. Herndon ◽  
Ella W. Englander

The effects of a 60% body surface area thermal injury in rats on the morphology and proliferation of the epithelium of the small intestine and the in vitro effects of serum collected from scalded rats on intestinal epithelial cells were investigated. Scald injury caused significant reductions in duodenal villus width and crypt dimensions, villus enterocytes changed in shape from columnar to cuboidal, and the number of goblet cells decreased. The proportion of bromodeoxyuridine-labeled S phase cells in crypts was also diminished. In vitro, incubation of intestinal epithelial cells (IEC-6) with scalded rat serum (SRS) collected at either 12 or 24 h after injury caused a disruption in the integrity of the confluent culture and induced the appearance of large denuded areas. SRS also decreased DNA synthesis and delayed wound closure in an in vitro wound-healing model. The thermal injury-induced changes in intestinal mucosal morphology and epithelial cell growth characteristics described in this study may underlie, in part, the mechanism(s) involved in the diminished absorption of nutrients, increased intestinal permeability, and sepsis in patients with thermal injury.


Cornea ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Di Chen ◽  
Jingyi Wang ◽  
David A. Sullivan ◽  
Wendy R. Kam ◽  
Yang Liu

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 4744-4744 ◽  
Author(s):  
R. Khafagy ◽  
T. Stephens ◽  
C. Hart ◽  
V. Ramani ◽  
M. Brown ◽  
...  

2008 ◽  
Vol 22 (2) ◽  
pp. 125-129 ◽  
Author(s):  
Ching-Yin Ho ◽  
Meng-Chuan Wu ◽  
Ming-Ying Lan ◽  
Ching-Ting Tan ◽  
An-Hang Yang

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