Insulin and insulin-like growth factor-1 promote mast cell survival via activation of the phosphatidylinositol-3-kinase pathway

Experimental Hematology ◽

10.1016/j.exphem.2006.05.022 ◽

2006 ◽

Vol 34 (11) ◽

pp. 1532-1541 ◽

Author(s):

Eva Lessmann ◽

Gordon Grochowy ◽

Lars Weingarten ◽

Torsten Giesemann ◽

Klaus Aktories ◽

...

Keyword(s):

Mast Cell ◽

Growth Factor ◽

Cell Survival ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival

Molecular Cancer ◽

10.1186/1476-4598-8-95 ◽

2009 ◽

Vol 8 (1) ◽

pp. 95 ◽

Author(s):

Jin-e Yao ◽

Min Yan ◽

Zhong Guan ◽

Chao-bin Pan ◽

Liang-ping Xia ◽

...

Keyword(s):

Growth Factor ◽

Cell Survival ◽

Cancer Cell ◽

Insulin Like Growth Factor ◽

Aurora A ◽

Phosphatidylinositol 3 Kinase ◽

Akt Activation ◽

Cancer Cell Survival ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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The Phosphatidylinositol-3 kinase Pathway Is Not Essential for Insulin-like Growth Factor I Receptor-mediated Clonogenic Radioresistance

Journal of Radiation Research ◽

10.1269/jrr.43.325 ◽

2002 ◽

Vol 43 (3) ◽

pp. 325-329 ◽

Author(s):

DONG YU ◽

HIROSHI WATANABE ◽

HITOSHI SHIBUYA ◽

MASAHIKO MIURA

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Growth Factor I ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Insulin-Like Growth Factor (IGF) Binding Protein-3 Potentiation of IGF Action Is Mediated through the Phosphatidylinositol-3-Kinase Pathway and Is Associated with Alteration in Protein Kinase B/AKT Sensitivity*

Endocrinology ◽

10.1210/endo.141.9.7660 ◽

2000 ◽

Vol 141 (9) ◽

pp. 3098-3103 ◽

Author(s):

C. A. Conover ◽

L. K. Bale ◽

S. K. Durham ◽

D. R. Powell

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Protein Kinase B ◽

Binding Protein ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Igf Binding ◽

Igf Binding Protein ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Synergistic Roles of Neuregulin-1 and Insulin-like Growth Factor-I in Activation of the Phosphatidylinositol 3-Kinase Pathway and Cardiac Chamber Morphogenesis

Journal of Biological Chemistry ◽

10.1074/jbc.274.52.37362 ◽

1999 ◽

Vol 274 (52) ◽

pp. 37362-37369 ◽

Author(s):

Cecilia M. Hertig ◽

Steven W. Kubalak ◽

Yibin Wang ◽

Kenneth R. Chien

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Cardiac Chamber ◽

Neuregulin 1 ◽

Factor I ◽

Growth Factor I ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Overexpression of Insulin-Like Growth Factor Binding Protein-5 Helps Accelerate Progression to Androgen-Independence in the Human Prostate LNCaP Tumor Model through Activation of Phosphatidylinositol 3′-Kinase Pathway*

Endocrinology ◽

10.1210/endo.141.6.7520 ◽

2000 ◽

Vol 141 (6) ◽

pp. 2257-2265 ◽

Author(s):

Hideaki Miyake ◽

Colleen Nelson ◽

Paul S. Rennie ◽

Martin E. Gleave

Keyword(s):

Growth Factor ◽

Binding Protein ◽

Tumor Model ◽

Human Prostate ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Androgen Independence ◽

Factor Binding ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Insulin-like growth factor binding protein-3 stimulates phosphatidylinositol 3-kinase in MCF-7 breast carcinoma cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2004.01.001 ◽

2004 ◽

Vol 314 (4) ◽

pp. 1044-1049 ◽

Author(s):

Jean-Marc Ricort ◽

Michel Binoux

Keyword(s):

Growth Factor ◽

Breast Carcinoma ◽

Binding Protein ◽

Carcinoma Cells ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor Binding ◽

Breast Carcinoma Cells ◽

Mcf 7 ◽

Phosphatidylinositol 3

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Activation of Vascular Endothelial Growth Factor Receptor-1 Sustains Angiogenesis and Bcl-2 Expression Via the Phosphatidylinositol 3-Kinase Pathway in Endothelial Cells

Diabetes ◽

10.2337/diabetes.52.12.2959 ◽

2003 ◽

Vol 52 (12) ◽

pp. 2959-2968 ◽

Author(s):

J. Cai ◽

S. Ahmad ◽

W. G. Jiang ◽

J. Huang ◽

C. D. Kontos ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Endothelial Cells ◽

Growth Factor ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Phosphatidylinositol 3 Kinase ◽

Endothelial Growth Factor ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor.

Endocrinology ◽

10.1210/endo.130.3.1311242 ◽

1992 ◽

Vol 130 (3) ◽

pp. 1490-1498 ◽

Author(s):

K Yamamoto ◽

E G Lapetina ◽

C P Moxham

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Insulin-like growth factor-1-mediated association of p85 phosphatidylinositol 3-kinase with pp 185: requirement of SH2 domains for in vivo interaction.

Molecular Endocrinology ◽

10.1210/mend.8.9.7838146 ◽

1994 ◽

Vol 8 (9) ◽

pp. 1139-1146

Author(s):

D Altschuler ◽

K Yamamoto ◽

E G Lapetina

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Sh2 Domains ◽

Phosphatidylinositol 3

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Myostatin Induces Cyclin D1 Degradation to Cause Cell Cycle Arrest through a Phosphatidylinositol 3-Kinase/AKT/GSK-3β Pathway and Is Antagonized by Insulin-like Growth Factor 1

Journal of Biological Chemistry ◽

10.1074/jbc.m610185200 ◽

2007 ◽

Vol 282 (6) ◽

pp. 3799-3808 ◽

Author(s):

Wei Yang ◽

Yong Zhang ◽

Yanfeng Li ◽

Zhenguo Wu ◽

Dahai Zhu

Keyword(s):

Growth Factor ◽

Cyclin D1 ◽

Cell Cycle Arrest ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Cycle Arrest ◽

Gsk 3Β ◽

Phosphatidylinositol 3

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