1-Phenyl-3-toluyl-4-[ortho-1′-(N-ethyl-2′-methylpropylamine)]phenylpyrazole, synthesis and evaluation of the in vitro antifungal activity against Botrytis cinerea and Fusarium oxysporum

Il Farmaco ◽  
2004 ◽  
Vol 59 (9) ◽  
pp. 673-678 ◽  
Author(s):  
Zainaba Dardari ◽  
Mohammed Boudouma ◽  
Abdelfatah Sebban ◽  
Abdelmejid Bahloul ◽  
Said Kitane ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Fusarium Oxysporum ◽  
Botrytis Cinerea ◽  
In Vitro Antifungal Activity

scholarly journals Antifungal activity of saponins originated from Medicago hybrida against some ornamental plant pathogens

2012 ◽  
Vol 59 (2) ◽  
pp. 51-58 ◽  
Author(s):  
Alicja Saniewska ◽  
Anna Jarecka ◽  
Zbigniew Biały ◽  
Marian Jurzysta
Keyword(s):  
Antifungal Activity ◽  
Fusarium Oxysporum ◽  
Botrytis Cinerea ◽  
Plant Pathogens ◽  
Pathogenic Fungi ◽  
Ornamental Plant ◽  
Mycelium Growth ◽  
Medicagenic Acid ◽  
Fungitoxic Effect

Antifungal activity of total saponins originated from roots of <i>Medicago hybrida</i> (Pourret) Trautv. were evaluated <i>in vitro</i> against six pathogenic fungi and eight individual major saponin glycosides were tested against one of the most susceptible fungi. The total saponins showed fungitoxic effect at all investigated concentrations (0.01%, 0.05% and 0.1%) but their potency was different for individual fungi. The highest saponin concentration (0.1%) was the most effective and the inhibition of <i>Fusarium oxysporum</i> f. sp. <i>callistephi</i>, <i>Botrytis cinerea</i>, <i>Botrytis tulipae</i>, <i>Phoma narcissi</i>, <i>Fusarium oxysporum</i> f. sp. <i>narcissi</i> was 84.4%, 69.9%, 68.6%, 57.2%, 55.0%, respectively. While <i>Fusarium oxysporum</i> Schlecht., a pathogen of <i>Muscari armeniacum</i>, was inhibited by 9.5% only. Eight major saponin glycosides isolated from the total saponins of <i>M. hybrida</i> roots were tested against the mycelium growth of <i>Botrytis tulipae</i>. The mycelium growth of the pathogen was greatly inhibited by hederagenin 3-O-<i>β</i>-D-glucopyranoside and medicagenic acid 3-O-<i>β</i>-D-glucopyranoside. Medicagenic acid 3-O-<i>β</i>-D-glucuronopyranosyl-28-O-<i>β</i>-D-glucopyranoside and oleanolic acid 3-O-[<i>β</i>-D-glucuronopyranosyl(1→2)-<i>α</i>-L-galactopyranosyl]-28-O-<i>β</i>-D-glucopyranoside showed low fungitoxic activity. Medicagenic acid 3-O-a-D-glucopyranosyl- 28-O-β-D-glucopyranoside, hederagenin 3-O-[α-L- hamnopyranosyl(1→2)-β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl]- 28-O-α-D-glucopyranoside and hederagenin 3-O-<i>β</i>-D-glucuronopyranosyl-28-O-<i>β</i>-D- lucopyranoside did not limit or only slightly inhibited growth of the tested pathogen. While 2<i>β</i>, 3<i>β</i>-dihydroxyolean-12 ene-23-al-28-oic acid 3-O-<i>β</i>-D-glucuronopyranosyl-28-O-<i>β</i>-D-glucopyranoside slightly stimulated mycelium growth of <i>B. tulipae</i>.

scholarly journals Synthesis of New Hydrated Geranylphenols and in Vitro Antifungal Activity against Botrytis cinerea

2016 ◽  
Vol 17 (6) ◽  
pp. 840 ◽  
Author(s):  
Mauricio Soto ◽  
Luis Espinoza ◽  
María Chávez ◽  
Katy Díaz ◽  
Andrés Olea ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Botrytis Cinerea ◽  
In Vitro Antifungal Activity

scholarly journals Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Hana Ighachane ◽  
Brahim Boualy ◽  
Mustapha Ait Ali ◽  
My. H. Sedra ◽  
Larbi El Firdoussi ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Fusarium Oxysporum ◽  
Verticillium Dahliae ◽  
Catalytic Synthesis ◽  
In Vitro Antifungal Activity

Various unsaturated natural terpenes were selectively converted to the corresponding polychlorinated products in good yields using iron acetylacetonate in combination with nucleophilic cocatalyst. The synthesized compounds were evaluated for their in vitro antifungal activity. The antifungal bioassays showed that 2c and 2d possessed significant antifungal activity against Fusarium oxysporum f. sp. albedinis (Foa), Fusarium oxysporum f. sp. canariensis (Foc), and Verticillium dahliae (Vd).

scholarly journals In Vitro Antifungal Activity of the Diterpenoid 7α-Hydroxy-8(17)-labden-15-oic Acid and Its Derivatives against Botrytis cinerea

Molecules ◽  
2009 ◽  
Vol 14 (6) ◽  
pp. 1966-1979 ◽  
Author(s):  
Leonora Mendoza ◽  
Pamela Espinoza ◽  
Alejandro Urzua ◽  
Marcela Vivanco ◽  
Milena Cotoras
Keyword(s):  
Antifungal Activity ◽  
Botrytis Cinerea ◽  
In Vitro Antifungal Activity

scholarly journals In vitro ANTIFUNGAL ACTIVITY OF SOME PLANT EXTRACTS AGAINST Fusarium oxysporum IN BLACKCURRANT (Ribes nigrum L.)

2017 ◽  
Vol 16 (6) ◽  
pp. 167-176 ◽  
Author(s):  
Tatiana Eugenia Şesan ◽  
Elena Enache ◽  
Beatrice Michaela Iacomi ◽  
Maria Oprea ◽  
Florin Oancea ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Fusarium Oxysporum ◽  
Plant Extracts ◽  
Ribes Nigrum ◽  
In Vitro Antifungal Activity

Efficacy of Essential Oil and Hydrosol Extract of Marrubium vulgare on Fungi Responsible for Apples Rot

2020 ◽  
Vol 18 (3) ◽  
pp. 285-293
Author(s):  
Amina Tabet Zatla ◽  
Imane Mami ◽  
Mohammed El Amine Dib ◽  
Mohammed El Amine Sifi
Keyword(s):  
Antifungal Activity ◽  
Essential Oil ◽  
Botrytis Cinerea ◽  
Alternaria Alternata ◽  
Penicillium Expansum ◽  
Caryophyllene Oxide ◽  
Marrubium Vulgare ◽  
In Vitro Antifungal Activity

Background: The microorganisms such as Penicillium expansum and Botrytis cinerea are wellknown pathogens in apples during postharvest. So, to protect apples from these pathogens, chemical control methods were exercised. Introduction: The main objective of this work was to study the chemical composition and the in-vitro and in-vivo antifungal properties of essential oil and hydrosol extract of Marrubium vulgare. Methods: In this work, the air-dried aerial parts of Marrubium vulgare were hydrodistilled in a Clevengertype apparatus. The essential oil and hydrosol extract isolated were analyzed using Gas Chromatography (GC) and Mass Spectrometry (GC/MS). The in-vitro antifungal activity of the both extracts was investigated against Botrytis cinerea, Penicillium expansum and Alternaria alternata fungi using radial growth technique. The effect of the essential oil and hydrosol extract on disease development of apple caused by Penicillium expansum in the in-vivo conditions was assessed. Results: The essential oil of Marrubium vulgare was characterized principally by E-β-caryophyllene (23.5%), E-β-farnesene (21%), α-humulene (14.8%), β-bisabolene (11.1%), caryophyllene oxide (6.8%) and phytol (3.1%). While, the methyl-eugenol (65.5%), α-Bisabolol (12.5%), linalool (6.5%) and caryophyllene oxide (6.2%) were the major compounds of hydrosol extract. The result of in-vitro antifungal activity of hydrosol extract showed an interesting antifungal inhibition against Botrytis cinerea, Penicillium expansum and Alternaria alternata with percentage inhibition ranging from 77% to 89% at low concentration of 0.15 mL/L. The essential oil was found to inhibit the growth of Penicillium expansum in a dose-dependent manner, with a percentage inhibition of 100% at 30 mL/L. Furthermore, essential oil and hydrosol extract have demonstrated promising in-vivo antifungal activity to control infection of apples by Penicillium expansum up to 25th day of storage, compared with the control. Conclusion: The preventive and protective effects of essential oil and hydrosol extract could be exploited as an ideal alternative to synthetic fungicides for using the protection of stored apples from fungal phytopathogens.

Sign in / Sign up

Export Citation Format

Share Document