α-Actinin4 nuclear translocation mediates gonadotropin-releasing hormone stimulation of follicle-stimulating hormone β-subunit gene transcription in LβT2 cells

FEBS Letters ◽  
2012 ◽  
Vol 586 (10) ◽  
pp. 1466-1471 ◽  
Author(s):  
Han Yu ◽  
Zhengjun Li ◽  
Dipanjana Ghosh ◽  
Teck Kwang Lim ◽  
Yuehui He ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Nuclear Translocation ◽  
Follicle Stimulating Hormone ◽  
Gonadotropin Releasing Hormone ◽  
Β Subunit ◽  
Subunit Gene ◽  
Releasing Hormone ◽  
Hormone Stimulation ◽  
Stimulation Of ◽  
Stimulating Hormone

scholarly journals Regulation of gonadotropin subunit gene transcription

2004 ◽  
Vol 33 (3) ◽  
pp. 559-584 ◽  
Author(s):  
L L Burger ◽  
D J Haisenleder ◽  
A C Dalkin ◽  
J C Marshall
Keyword(s):  
Transcriptional Regulation ◽  
Luteinizing Hormone ◽  
Gene Transcription ◽  
Sexual Maturation ◽  
Follicle Stimulating Hormone ◽  
Reproductive Function ◽  
Gonadotropin Releasing Hormone ◽  
Subunit Gene ◽  
Pulsatile Release ◽  
Releasing Hormone

Reproductive function in mammals is regulated by the pituitary gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH are secreted by the gonadotrope cell and act on the gonad in a sequential and synergistic manner to initiate sexual maturation and maintain cyclic reproductive function. The synthesis and secretion of LH and FSH are regulated mainly by the pulsatile release of the hypothalamic decapeptide hormone gonadotropin-releasing hormone (GnRH). The control of differential LH and FSH synthesis and secretion is complex and involves the interplay between the gonads, hypothalamus and pituitary. In this review, the transcriptional regulation of the gonadotropin subunit genes is discussed in a physiologic setting, and we aimed to examine the mechanisms that drive those changes.

scholarly journals Human Follicle-Stimulating Hormone β-Subunit Gene Encodes Multiple Messenger Ribonucleic Acids

1988 ◽  
Vol 2 (9) ◽  
pp. 806-815 ◽  
Author(s):  
J. Larry Jameson ◽  
Carolyn B. Becker ◽  
Christine M. Lindell ◽  
Joel F. Habener
Keyword(s):  
Follicle Stimulating Hormone ◽  
Β Subunit ◽  
Subunit Gene ◽  
Ribonucleic Acids ◽  
Stimulating Hormone
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