Molecular reaction mechanism for elimination of zearalenone during simulated alkali neutralization process of corn oil

2020 ◽  
Vol 307 ◽  
pp. 125546 ◽  
Author(s):  
Chuan-Guo Ma ◽  
Ying-Dan Wang ◽  
Wei-Feng Huang ◽  
Jun Liu ◽  
Xiao-Wei Chen
Keyword(s):  
Reaction Mechanism ◽  
Corn Oil ◽  
Molecular Reaction ◽  
Neutralization Process ◽  
Alkali Neutralization

scholarly journals Reaction of the aminic form of aspartate transaminase with difluoro-oxaloacetate

1977 ◽  
Vol 167 (1) ◽  
pp. 193-200 ◽  
Author(s):  
P A Briley ◽  
R Eisenthal ◽  
R Harrison ◽  
G D Smith
Keyword(s):  
Reaction Mechanism ◽  
Reaction Scheme ◽  
Aspartate Transaminase ◽  
Fast Reaction ◽  
Spectral Parameters ◽  
Absorbance Maximum ◽  
Molecular Reaction ◽  
Basic Reaction ◽  
Enzyme Complexes ◽  
Rapid Shift

Addition of difluoro-oxaloacetate to the aminic form of aspartate transaminase causes a rapid shift of absorbance maximum of the enzyme from 332 nm to 328 nm, followed by a much slower shift to 360 nm corresponding to complete conversion of the aminic form of the enzyme into the aldimine form or a species with similar spectral parameters in rapid equilibrium with it. Kinetic analysis of both the initial fast reaction and the overall slow reaction by using repeated spectral scanning and stopped-flow techniques allows formulation of a basic reaction mechanism involving at least two intermediate enzyme complexes. Computer simulation of the progress curves of the initial fast reaction based on the suggested reaction mechanism gives kinetic parameters that are consistent with all the data obtained by other methods. A molecular reaction scheme involving a ketimine Schiff-base intermediate is proposed.

Molecular Reaction Mechanism for the Formation of 3-Chloropropanediol Esters in Oils and Fats

2019 ◽  
Vol 67 (9) ◽  
pp. 2700-2708 ◽  
Author(s):  
Yunping Yao ◽  
Ruizhi Cao ◽  
Wentao Liu ◽  
Hang Zhou ◽  
Changmo Li ◽  
...  
Keyword(s):  
Reaction Mechanism ◽  
Molecular Reaction

Ultrastructural Effects of Acute Kepone Treatment in Rats

1976 ◽  
Vol 34 ◽  
pp. 286-287
Author(s):  
Richard L. Klein ◽  
Åsa K. Thureson-Klein ◽  
Harihara M. Mehendale
Keyword(s):  
Neurological Disorders ◽  
Corn Oil ◽  
Preliminary Investigation ◽  
Reproductive Capacity ◽  
Ultrastructural Changes ◽  
Lipid Deposition ◽  
Severe Toxicity ◽  
Sprague Dawley ◽  
Ether Anesthesia ◽  
Sprague Dawley Rats

KeponeR (decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalen-2-one) is an insecticide effective against ants and roaches. It can cause severe toxicity in fishes, birds, rodents and man. Prominent effects include hepatic lipid deposition and hypertrophy, impairment of reproductive capacity and neurological disorders. Mitochondrial oligomycin-sensitive Mg2+-ATPase is also inhibited. The present study is a preliminary investigation of tissue ultrastructural changes accompanying physiological signs of acute toxicity, which after two days treatment include: pronounced hypersensitivity and tremor, various degrees of anorexia and adipsia, and decreased weight gain.Three different series of adult male Sprague-Dawley rats (Charles River or CD-I) were treated by intubation with Kepone in corn oil at a dose of 50 mg per kg for 3 successive days or at 200 ppm in food for 8 days. After ether anesthesia, rats were immediately perfused via a cannula in the left ventricle with 4% p-formaldehyde and 0.5% glutaraldehyde in Millonig's phosphate buffer at pH 7.2 for 20-30 min at 22°C.

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