Insight into stress-induced cardiomyopathy and sudden cardiac death due to stress. A forensic cardio-pathologist point of view

2010 ◽  
Vol 194 (1-3) ◽  
pp. 1-8 ◽  
Author(s):  
Vittorio Fineschi ◽  
Manolis Michalodimitrakis ◽  
Stefano D’Errico ◽  
Margherita Neri ◽  
Cristoforo Pomara ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Point Of View ◽  
Insight Into

scholarly journals A New Insight Into Sudden Cardiac Death in Young People

Medicine ◽  
2015 ◽  
Vol 94 (32) ◽  
pp. e1174 ◽  
Author(s):  
Yueyue Wang ◽  
Lei Xia ◽  
Xiaodong Shen ◽  
Guoxin Han ◽  
Dan Feng ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Young People ◽  
Cardiac Death ◽  
Insight Into

scholarly journals Sudden Cardiac Death—A New Insight Into Potentially Fatal Genetic Markers

2021 ◽  
Vol 8 ◽  
Author(s):  
Dragan Primorac ◽  
Ljubica Odak ◽  
Vitorio Perić ◽  
Jasmina Ćatić ◽  
Jozica Šikić ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Laboratory Data ◽  
Scientific Paper ◽  
Genetic Etiology ◽  
Cardiac Symptoms ◽  
History Of ◽  
Football Field ◽  
Insight Into ◽  
Professional Footballer

Sudden cardiac death (SCD) is an unexpected and dramatic event. It draws special attention especially in young, seemingly healthy athletes. Our scientific paper is based on the death of a young, 23-year-old professional footballer, who died on the football field after a two-year history of cardiac symptoms. In this study we analyzed clinical, ECG and laboratory data, as well as results of genetic testing analysis in family members. To elucidate potential genetic etiology of SCD in this family, our analysis included 294 genes related to various cardiac conditions.

scholarly journals GENE EXPRESSION PATTERN ANALYSIS FOR FORENSIC DIAGNOSIS OF SUDDEN CARDIAC DEATH

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Saikat Das ◽  
Ritwik Ghosh ◽  
Soumeek Chowdhuri
Keyword(s):  
Gene Expression ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Connexin 43 ◽  
Gene Expression Pattern ◽  
Protein Markers ◽  
Zonula Occludens ◽  
Current Scenario ◽  
Hemoglobin A1 ◽  
Insight Into

Diagnosis of Sudden cardiac death (SCD) is challenging for forensic experts. In the current scenario, genetic analysis is rapidly gaining interest in forensic science. Previous studies are not only limited to using protein markers. In this regard, analysis of mRNA is also a key feature. Analysing mRNA offers insight into the diseases and mechanisms leading to death. It can also be used for forensic diagnostic purposes. This review article takes the help of this methodology to discuss about those mRNA species that can aid in the process of sudden cardiac death (SCD) diagnosis. These are mRNA encoding Heat Shock Protein (HSP), mRNA encoding Hemoglobin A1/2 & B, mRNA encoding Pyruvate Dehydrogenase (PDK4), mRNAs encoding Connexin 43 (Cx43) & Zonula occludens-1 (ZO1), mRNA encoding TNNI3, MYL3, TGFB1, MMP9, VEGFA and mRNA expressing Brain Natriuretic Peptide (BNP).Owing to the difficulty of diagnosing SCD, molecular markers are often developed that can aid in the process. Nowadays, mRNA is showing promising usefulness to supplement the process. Keywords: Sudden Cardiac Death, forensic, gene expression

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