scholarly journals Sudden cardiac death in a woman with clinical evidence of coronary vasospastic disease and myocardial stunning. A necrospy insight into the etiology

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Carlo Caiati ◽  
Mario Erminio Lepera ◽  
Andrea Marzullo ◽  
Stefano Favale
2015 ◽  
Vol 24 (1) ◽  
pp. 42-53 ◽  
Author(s):  
Eric Tien Siang Lim ◽  
Aaron Sung Lung Wong ◽  
Nur Shahidah binte Ahmad ◽  
Kenneth Boon Kiat Tan ◽  
Marcus Eng Hock Ong ◽  
...  

2005 ◽  
Vol 10 (4_suppl) ◽  
pp. S23-S31 ◽  
Author(s):  
Stefan H. Hohnloser

Patients who have had a recent myocardial infarction (MI) are at high risk of ventricular arrhythmias that often cause sudden cardiac death. It is believed that sympathetic overactivity in the peri-infarction period may alter the electrophysiology and structure of the myocardium, thus placing these patients at risk of developing rhythm disturbances. A number of pharmacologic and nonpharmacologic therapies have been shown to reduce the risk of post-MI mortality, including sudden cardiac death. β-Adrenergic blockers are recommended for all post-MI patients without contraindications because of overwhelming clinical evidence of their benefit in reducing mortality in this patient population. Recent clinical trials of implantable cardioverter defibrillators have provided compelling support that they are effective in both the primary and secondary prevention of sudden cardiac death. In addition, several studies have shown that combination therapy with β-blockers and implantable cardioverter defibrillators have synergistic effects that optimize the benefits of both therapies.


Medicine ◽  
2015 ◽  
Vol 94 (32) ◽  
pp. e1174 ◽  
Author(s):  
Yueyue Wang ◽  
Lei Xia ◽  
Xiaodong Shen ◽  
Guoxin Han ◽  
Dan Feng ◽  
...  

2010 ◽  
Vol 194 (1-3) ◽  
pp. 1-8 ◽  
Author(s):  
Vittorio Fineschi ◽  
Manolis Michalodimitrakis ◽  
Stefano D’Errico ◽  
Margherita Neri ◽  
Cristoforo Pomara ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Dragan Primorac ◽  
Ljubica Odak ◽  
Vitorio Perić ◽  
Jasmina Ćatić ◽  
Jozica Šikić ◽  
...  

Sudden cardiac death (SCD) is an unexpected and dramatic event. It draws special attention especially in young, seemingly healthy athletes. Our scientific paper is based on the death of a young, 23-year-old professional footballer, who died on the football field after a two-year history of cardiac symptoms. In this study we analyzed clinical, ECG and laboratory data, as well as results of genetic testing analysis in family members. To elucidate potential genetic etiology of SCD in this family, our analysis included 294 genes related to various cardiac conditions.


2016 ◽  
Vol 02 (01) ◽  
pp. 20
Author(s):  
Pier D Lambiase ◽  

The subcutaneous implantable cardioverter-defibrillator (S-ICD) is emerging as an important adjunct in the prevention of sudden cardiac death avoiding the long-term complications of transvenous leads. This editorial reviews that past year of developments, new clinical evidence and what the future challenges are in this field.


Author(s):  
Saikat Das ◽  
Ritwik Ghosh ◽  
Soumeek Chowdhuri

Diagnosis of Sudden cardiac death (SCD) is challenging for forensic experts. In the current scenario, genetic analysis is rapidly gaining interest in forensic science. Previous studies are not only limited to using protein markers. In this regard, analysis of mRNA is also a key feature. Analysing mRNA offers insight into the diseases and mechanisms leading to death. It can also be used for forensic diagnostic purposes. This review article takes the help of this methodology to discuss about those mRNA species that can aid in the process of sudden cardiac death (SCD) diagnosis. These are mRNA encoding Heat Shock Protein (HSP), mRNA encoding Hemoglobin A1/2 & B, mRNA encoding Pyruvate Dehydrogenase (PDK4), mRNAs encoding Connexin 43 (Cx43) & Zonula occludens-1 (ZO1), mRNA encoding TNNI3, MYL3, TGFB1, MMP9, VEGFA and mRNA expressing Brain Natriuretic Peptide (BNP).Owing to the difficulty of diagnosing SCD, molecular markers are often developed that can aid in the process. Nowadays, mRNA is showing promising usefulness to supplement the process. Keywords: Sudden Cardiac Death, forensic, gene expression


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