Phenotypic changes in human coronary artery smooth muscles cells cultured on peroxynitrous acid-modified extracellular matrix

2021 ◽  
Vol 177 ◽  
pp. S101
Author(s):  
Sara M. Jørgensen ◽  
Christine Y. Chuang ◽  
Michael J. Davies
Keyword(s):  
Extracellular Matrix ◽  
Coronary Artery ◽  
Smooth Muscles ◽  
Peroxynitrous Acid ◽  
Human Coronary Artery ◽  
Phenotypic Changes ◽  
Cells Cultured

The function of intimal longitudinal smooth muscles of the human coronary artery

1986 ◽  
Vol 42 (11-12) ◽  
pp. 1222-1224 ◽  
Author(s):  
K. Kawasaki ◽  
T. Iino ◽  
H. Hasegawa ◽  
I. Miyazawa ◽  
S. Hosoda
Keyword(s):  
Coronary Artery ◽  
Smooth Muscles ◽  
Human Coronary Artery

Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

2014 ◽  
Vol 459 (2) ◽  
pp. 313-322 ◽  
Author(s):  
Christine Y. Chuang ◽  
Georg Degendorfer ◽  
Astrid Hammer ◽  
John M. Whitelock ◽  
Ernst Malle ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cardiovascular Disease ◽  
Extracellular Matrix ◽  
Arterial Wall ◽  
Structure And Function ◽  
Wall Structure ◽  
Peroxynitrous Acid ◽  
Human Coronary Artery ◽  
Cell Matrix ◽  
And Function

The extracellular matrix determines arterial wall structure and modulates the properties of associated cells. We show that the inflammation-associated oxidant peroxynitrous acid modifies human endothelial cell matrix, modulates gene expression and decreases cell adhesion, a key event in cardiovascular disease.

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