Associations of IGF-1 gene variants and milk protein intake with IGF-I concentrations in infants at age 6months — Results from a randomized clinical trial

2013 ◽  
Vol 23 (5) ◽  
pp. 149-158 ◽  
Author(s):  
Peter Rzehak ◽  
Veit Grote ◽  
Eva Lattka ◽  
Martina Weber ◽  
Dariusz Gruszfeld ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Protein Intake ◽  
Milk Protein ◽  
Gene Variants ◽  
Igf I

scholarly journals Milk protein intake, the metabolic-endocrine response, and growth in infancy: data from a randomized clinical trial

2011 ◽  
Vol 94 (suppl_6) ◽  
pp. 1776S-1784S ◽  
Author(s):  
◽  
Piotr Socha ◽  
Veit Grote ◽  
Dariusz Gruszfeld ◽  
Roman Janas ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Protein Intake ◽  
Milk Protein ◽  
Endocrine Response

scholarly journals Modifications of Own Mothers’ Milk Fortification Protocol Affect Early Plasma IGF-I and Ghrelin Levels in Preterm Infants. A Randomized Clinical Trial

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 3056
Author(s):  
Eleni Agakidou ◽  
Thomais Karagiozoglou-Lampoudi ◽  
Elisavet Parlapani ◽  
Dimitrios J. Fletouris ◽  
Kosmas Sarafidis ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Preterm Infants ◽  
Plasma Levels ◽  
Protein Intake ◽  
Protein Targeting ◽  
Growth Parameter ◽  
Transient Effect ◽  
Protein Energy ◽  
Igf I ◽  
Z Scores

The aim was to investigate the effect of two own mother’s milk (OMM) fortification protocols on (a) IGF-I and ghrelin plasma levels at 35 post-conceptional weeks (PCW, T2) and whether this effect is maintained after elimination of the differences in OMM fortification, and (b) growth until 12 months corrected age. Forty-eight OMM-fed preterm infants (GA 24–32 weeks) were randomly allocated to the fixed-fortification (FF) group (n = 23) and the protein-targeting fortification (PTF) group (n = 25) targeting the recommended daily protein intake (PI). Plasma IGF-I and ghrelin were assessed at 35 (T2) and 40 (T3) PCW while growth was longitudinally assessed until 12 months corrected age. PTF group had lower IGF-I and higher ghrelin than FF group at T2, while receiving lower daily protein and energy amounts. PI correlated positively to T2-IGF-I and inversely to T3-ghrelin while energy intake (EI) correlated inversely to T2- and T3-ghrelin. Group and PI were independent predictors of adjusted T2-IGF-I, while group and EI were predictors of adjusted and T2-ghrelin. Growth parameter z-scores were comparable between groups up to 12 months corrected age. Modifications of OMM fortification have a transient effect on early plasma IGF-I and ghrelin levels in preterm infants in a way consistent with the previously recognized protein-energy/endocrine balance, indicating a potential programming effect.

The IGF-I system and the renal and haemodynamic effects of losartan in normotensive patients with type 2 diabetes mellitus: a randomized clinical trial

2006 ◽  
Vol 64 (2) ◽  
pp. 203-208 ◽  
Author(s):  
Adrienne A. M. Zandbergen ◽  
Steven W. J. Lamberts ◽  
Marinus G. A. Baggen ◽  
Joop A. M. J. L. Janssen ◽  
Eric Boersma ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Type 2 Diabetes Mellitus ◽  
Randomized Clinical Trial ◽  
Haemodynamic Effects ◽  
Igf I

Randomized clinical trial of LigasureTM versus open haemorrhoidectomy

2002 ◽  
Vol 89 (2) ◽  
pp. 154-157 ◽  
Author(s):  
F. F Palazzo ◽  
D. L Francis ◽  
M. A Clifton
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial
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