Nicotine inhibits expression of Prrx1 in pituitary stem/progenitor cells through epigenetic regulation, leading to a delayed supply of growth-hormone-producing cells

2020 ◽  
Vol 51 ◽  
pp. 65-74
Author(s):  
Ayaka Hibara ◽  
Takahiro Yamaguchi ◽  
Miki Kojima ◽  
Yoshiaki Yamano ◽  
Masashi Higuchi
Keyword(s):  
Growth Hormone ◽  
Progenitor Cells ◽  
Epigenetic Regulation

scholarly journals Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. VOLUME 283 (2008) PAGES 27644-27652

2009 ◽  
Vol 284 (13) ◽  
pp. 8995
Author(s):  
Xuekun Li ◽  
Basam Z. Barkho ◽  
Jinfeng Bao ◽  
Yuping Luo ◽  
Richard D. Smrt ◽  
...  
Keyword(s):  
Stem Cell ◽  
Progenitor Cells ◽  
Epigenetic Regulation ◽  
Neural Stem Progenitor Cells ◽  
Cell Mitogen

scholarly journals Epigenetic regulation of kidney progenitor cells

2020 ◽  
Vol 9 (6) ◽  
pp. 655-660
Author(s):  
Biao Huang ◽  
Zhenqing Liu ◽  
Ariel Vonk ◽  
Zipeng Zeng ◽  
Zhongwei Li
Keyword(s):  
Progenitor Cells ◽  
Epigenetic Regulation

scholarly journals Epigenetic Regulation of Cardiac Progenitor Cells Marker c-kit by Stromal Cell Derived Factor-1α

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69134 ◽  
Author(s):  
Zhongpu Chen ◽  
Xiaodong Pan ◽  
Yuyu Yao ◽  
Fengdi Yan ◽  
Long Chen ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Epigenetic Regulation ◽  
Stromal Cell ◽  
Cardiac Progenitor Cells ◽  
Stromal Cell Derived Factor

The ontogenic and functional relationships between growth hormone- and prolactin-releasing cells during the development of the bovine pituitary

1992 ◽  
Vol 134 (1) ◽  
pp. 91-96 ◽  
Author(s):  
R. D. Kineman ◽  
W. J. Faught ◽  
L. S. Frawley
Keyword(s):  
Growth Hormone ◽  
Progenitor Cells ◽  
Gestational Age ◽  
Functional Relationship ◽  
Pituitary Cells ◽  
Hormone Release ◽  
Functional Relationships ◽  
Cells In Culture ◽  
Suggestive Evidence ◽  
Near Term

ABSTRACT The ontogeny of GH- and prolactin-releasing cells in the developing bovine pituitary was evaluated by reverse haemolytic plaque assays which allows for the detection of hormone release from individual pituitary cells in culture. With this approach, we observed that GH-releasing cells ontogenically preceded prolactin-releasing cells. In fact, GH secretors were observed as early as 59 days of gestational age while cells that released prolactin were not identified until 98 days. The amounts of both GH- and prolactinreleasing cells increased with time to reach more than 50% and 20% of all pituitary cells near term (term ∼280 days) respectively. Interestingly, the first cells shown to release prolactin also released GH (i.e. were mammosomatotropes). This temporal and functional relationship between GH and prolactin secretors provides suggestive evidence that GH-secreting cells act as the progenitor cells for prolactin secretors via a functional intermediate, the mammosomatotrope. Journal of Endocrinology (1992) 134, 91–96

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