scholarly journals The impact of screening method on HLA antibody detection before and after lung transplantation: A prospective pilot study

2018 ◽  
Vol 37 (4) ◽  
pp. 531-533 ◽  
Author(s):  
Severine Cao ◽  
Andrew M. Courtwright ◽  
Anthony M. Lamattina ◽  
Indira Guleria ◽  
Patrick Burkett ◽  
...  
Keyword(s):  
Pilot Study ◽  
Lung Transplantation ◽  
Screening Method ◽  
Antibody Detection ◽  
Prospective Pilot Study ◽  
Before And After ◽  
The Impact ◽  
Hla Antibody

scholarly journals THU0642-HPR EVOLUTION OF THE PERCEPTIONS OF RA PATIENTS AFTER EDUCATION PATIENT SESSION TEACHING METHOTREXATE SELF-INJECTION A PROSPECTIVE PILOT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 566.1-566
Author(s):  
S. Afilal ◽  
H. Rkain ◽  
B. Berchane ◽  
J. Moulay Berkchi ◽  
S. Fellous ◽  
...  
Keyword(s):  
Pilot Study ◽  
Patient Education ◽  
Median Duration ◽  
Large Scale ◽  
Education Session ◽  
Prospective Pilot Study ◽  
Mean Delay ◽  
Lack Of Information ◽  
Level Of Satisfaction ◽  
Before And After

Background:Methotrexate is a gold standard for treatment of RA. In our context, RA patients prefer to be injected by paramedics rather than self-injecting. This can be explained by patients’ bad perceptions of self-injection or lack of information. Appropriate self-injection education can therefore be an important element in overcoming these obstacles and improving disease self-management.Objectives:Compare the RA patients’ perceptions on methotrexate self-injection before and after a patient education session.Methods:Prospective pilot study that included 27 consecutive patients (81.5% female, mean age 44.4 years, illiteracy rate 40.7%) with RA (median duration of progression of 4 years, mean delay in referral for specialist of 6 months, median duration of methotrexate use of 1 year). The patients benefited from an individual patient education session to learn how to self-inject with methotrexate subcutaneously. The patient education session was supervised by a nurse and a rheumatologist with a control a week later. Perceptions of the reluctance to self-inject and the difficulties encountered by patients were assessed before the patient education session, after the 1st and 2nd self-injection of methotrexate using a 10 mm visual analog scale. Patients also reported their level of satisfaction (10 mm VAS) after the 1st and 2nd self-injection.Results:The mean duration of patient education session is 13 min.Table I compares the evolution of the degrees of reluctance to self-injection, the difficulties encountered, and the satisfaction experienced by the patients.Table 1.Evolution of RA patients’ perceptions on the methotrexate self-injection. (N = 27)BeforeAfter the 1stself-injectionAfter the 2end self-injectionpVAS reluctance (0-10mm)6,5 ± 3,62,2 ± 2,91,0 ± 2,3<0,0001VAS difficulty (0-10mm)7,5 ± 2,62,5 ± 2,71,0 ± 1,9<0,0001VAS satisfaction (0-10mm)-8,9 ± 1,89,5 ± 1,50,002Conclusion:This study suggests the effectiveness of a methotrexate self-injection patient education session in RA patients. It also highlights the value of patient education in rheumatologic care. A large-scale study is necessary to better interpret and complete these preliminary results from this pilot study.Disclosure of Interests:None declared

scholarly journals Development and Validation of a Questionnaire Evaluating the Impact of Prosthetic Dental Treatments on Patients’ Oral Health Quality of Life: A Prospective Pilot Study

2020 ◽  
Vol 17 (14) ◽  
pp. 5037 ◽  
Author(s):  
Eitan Mijiritsky ◽  
Yael Lerman ◽  
Ori Mijiritsky ◽  
Asaf Shely ◽  
Joseph Meyerson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Pilot Study ◽  
Post Treatment ◽  
Self Report ◽  
Measurement Tool ◽  
The Novel ◽  
Prospective Pilot Study ◽  
The Impact

Objectives: the aims of this study were the development of a novel questionnaire to assess the impact of prosthetic treatments on oral health-related quality of life (OHRQoL) and the performance of a prospective pilot study. Background: the currently preferred OHRQoL measurement tool is the oral health impact profile-49 (OHIP-49), a self-report questionnaire which mainly focuses on general effects related to oral health. Materials and methods: A total of 24 adult participants (9 females and 15 males) were recruited and asked to complete the novel questionnaire twice: once before the prosthetic treatment began and 4–6 weeks post-treatment. The assessment of the change in OHRQoL was based on the differences in participants’ answers before and after treatment. Data were analyzed using ANOVA with a repeated-measures method and t-tests. The reliability of the questionnaire was tested using Cronbach’s alpha and intraclass coefficient (ICC). Results: The questionnaire was found to be reliable (α ≥ 0.6), with “social disability” having the highest score (α = 0.868). All domains showed an improvement (α < 0.005) in OHRQoL scores after treatment. Conclusions: the novel questionnaire tested in this study was found to be reliable and convenient to use, and demonstrated that prosthetic treatments have a significant positive effect on OHRQoL post-treatment scores.

scholarly journals Efficacy of a Gluten-Free Diet in the Gilles de la Tourette Syndrome: A Pilot Study

2018 ◽  
Author(s):  
Luis Rodrigo ◽  
Nuria Álvarez ◽  
Enrique Fernández-Bustillo ◽  
Javier Salas-Puig ◽  
Marcos Huerta ◽  
...  
Keyword(s):  
Pilot Study ◽  
Tourette Syndrome ◽  
Marked Reduction ◽  
Gluten Free Diet ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Prospective Pilot Study ◽  
Before And After ◽  
One Year

The Gilles de la Tourette syndrome (GTS) and Non-Coeliac Gluten Sensitivity (NCGS) may be associated. We analyse the efficacy of a gluten-free diet (GFD) in 29 patients with GTS (23 children; 6 adults) in a prospective pilot study. All of them followed a GFD for one year. The YGTSS, Y-BOCS/CY-BOCS and GTS-QOL questionnaires were compared before and after the GFD. 74% of children and 50% of adults were males, not significant (NS). At the beginning of the study, 69% of children and 100% of adults had associated OCD (NS). At baseline, the YGTSS scores were 55.0 &plusmn; 17.5 (children) and 55.8 &plusmn; 19.8 (adults) (NS), the Y-BOCS/CY-BOCS scores were 15.3 (SD = 12.3) (children) and 26.8 (9.2) (adults) (p = 0.043), and the GTS-QOL scores were 42.8 &plusmn; 18.5 (children) and 64 &plusmn; 7.9 (adults) (p = 0.000). NCGS was frequent in both groups, with headaches reported by 47.0% of children and 83.6% of adults (p = 0.001). After one year on a GFD there was a marked reduction in measures of tics (YGTSS) (p = 0.001), and the intensity and frequency of OCD (Y-BOCS/CY-BOCS) (p = 0.001), along with improved QOL (p = 0.001) in children and adults. In conclusion, a GFD maintained for one year in GTS patients led to a marked reduction in tics and OCD both in children and adults.

A prospective pilot study to assess the impact of the etonogestrel implant on postpartum depression

2020 ◽  
pp. 1-7
Author(s):  
Carolyn M. Ross ◽  
Cassing Hammond ◽  
Jessika A. Ralph ◽  
Lauren C. Balmert ◽  
Katherine L. Wisner ◽  
...  
Keyword(s):  
Pilot Study ◽  
Postpartum Depression ◽  
Prospective Pilot Study ◽  
The Impact ◽  
Etonogestrel Implant

Grandchildren’s food workshop: Impact of an intergenerational cooking program on dietary habits, food courage, cooking skills and two-way interaction in Danish children and their grandparents

2021 ◽  
pp. 026010602199163
Author(s):  
Anne Marie Beck ◽  
Stine B. Nielsen ◽  
Kirsten S. Bjørnsbo
Keyword(s):  
Pilot Study ◽  
Dietary Habits ◽  
Age Groups ◽  
Cooking Skills ◽  
Before And After ◽  
Chi Squared ◽  
Good Nutrition ◽  
The Impact ◽  
Dietary Data

Background: Good nutrition is a key aspect of health. Cooking activities can improve dietary habits, cooking skills and food courage in terms of courage to cook and taste new foods, in individuals of all ages. However, targeting both grandchildren and grandparents at the same time through intergenerational cooking activities, is new. Aim: This paper aims to present the impact of intergenerational cooking activities on dietary habits, food courage, cooking skills and two-way interaction between young and old participants in The Grandchildren’s Food Workshop. Methods: In this observational pilot study, the Danish Heart Foundation’s experimental cooking program for grandchildren and grandparents was developed and tested. The influence of the food workshop on the participants’ dietary habits, food courage, cooking skills and two-way interaction was assessed by a before and after questionnaire. McNemar’s and chi-squared tests were used to evaluate the effects. Results: A total of 180 grandchildren (10 to 12 years) and 183 grandparents participated in The Grandchildren’s Food Workshop. A total of 82 (46%) grandchildren (71% of which were girls) and 125 (68%) grandparents (83% of which were women) responded to the baseline and follow-up questionnaires. The impact on dietary habits and food courage was limited, while there was an impact on cooking skills in the grandchildren. The already good two-way interaction was unaltered. Conclusions: The findings indicate an impact on cooking skills among grandchildren participating in The Grandchildren’s Food Workshop, while the impact on dietary habits, food courage and two-way interaction between age groups was limited. Further research, including more detailed dietary data, should explore the significance of an intergenerational approach.

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