scholarly journals Blood Lactate Level Evolution during Lung Transplantation

2021 ◽  
Vol 40 (4) ◽  
pp. S317
Author(s):  
J. Fessler ◽  
A. Vallee ◽  
A. Guirimand ◽  
M. Fischler ◽  
M. Le Guen
2007 ◽  
Vol 47 (4) ◽  
pp. 150 ◽  
Author(s):  
M. Tatang Puspanjono ◽  
Abdul Latief ◽  
Alan R. Tumbelaka ◽  
Sudigdo Sastroasmoro ◽  
Hartono Gunardi

Background Dengue shock syndrome (DSS) mortality is still high.Monitoring of blood lactate level is important to evaluate shock.Objectives The study were to review the difference between bloodlactate level of DSS and that of dengue hemorrhagic fever (DHF),to correlate blood lactate level with hypoxia state as shock riskfactors (PaO 2 , oxygen saturation, and anion gap) and to determinethe cut-off point of blood lactate level to predict shock.Methods The study was carried out at the Department of ChildHealth, Medical School, University of Indonesia, CiptoMangunkusumo Hospital, Jakarta, from January until July 2006.Three mL venous blood specimen was collected from all subjectsfor peripheral blood, blood gasses, serology, and blood lactateexaminations. This study consisted of a retrospective cohort anda cross sectional method. Data were analyzed with Chi-squaretest. Continous data tested using Mann-Whitney method. Toknow the correlation between blood lactate level and shock riskfactors we use logistic regression test.Results In DSS group, 73% shows hyperlactatemia (lactate =2mmol/L). Conversion of lactate means between two groups issignificantly different from day one to day two and three. Therewas a negative correlation between lactate level and pO 2 andoxygen saturation. Oxygen saturation is the only value that hasclinical correlation. Regressions analysis can be applied using Y= 7.05–0.05 X equation. The cut-off point of lactate level asmarker for shock by using ROC curve is 32.015 mmol/L with 70%sensitivity and 83.3% specificity.Conclusions Hyperlactatemia in DSS can be considered as a signfor unappropriate treatment of shock. Blood lactate level can beused as a biochemical marker for tissue hypoxia, to assess severityof the disease, as monitoring of treatment, and has prognosticvalue of DHF cases.


2009 ◽  
Vol 23 (5) ◽  
pp. 663-667 ◽  
Author(s):  
Sujata B. Chakravarti ◽  
Alexander J.C. Mittnacht ◽  
Jason C. Katz ◽  
Khahn Nguyen ◽  
Umesh Joashi ◽  
...  

2020 ◽  
Vol 86 (889) ◽  
pp. 19-00433-19-00433
Author(s):  
Takumi YAMAKAWA ◽  
Soichiro HAYAKAWA ◽  
Katsuhiro ASANO ◽  
Shigeyoshi TSUTSUMI ◽  
Ryojun IKEURA

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Naoto Morimura ◽  
Tetsuya Sakamoto ◽  
Kyoko Matsumori ◽  
Kohei Takahashi ◽  
Tomoki Doi ◽  
...  

Background: We developed a new device for quantifying capillary refill time (CRT) by applying the pulse oximeter principle, and reported the excellent correlation between quantitative CRT (Q-CRT) and tissue hypoperfusion status as represented by arterial blood lactate levels in critically ill patients in the pilot study. Methods: Diagnostic accuracy study was undergone in ICU of a tertiary emergency medical center. While the pulse oxygen saturation sensor was placed on the finger of the patients, transmitted light intensity was measured with a pulse oximeter (OLV-3100, Nihon Kohden Corp., Japan) before start and during compression of the finger. Correlation between delta Ab, defined as the absorbance of light intensity of infra-red (A-ir) minus that of red (A-r), and arterial blood lactate level was analyzed. Results: The delta Ab was analyzed a total of 69 waveforms in 23 patients. The sensitivity, specificity, positive predictive value, and negative predictive value of the delta Ab less than 0.06 for predicting a lactate level more than 2.0 mmol/l were 100%, 93%, 89%, 100%, respectively. Conclusions: The delta Ab was well correlated to high level of blood lactate level in critically ill patients. Further study will confirm to place the delta Ab as one of non-invasive predictors of tissue perfusion status.


2016 ◽  
Vol 30 (5) ◽  
pp. 1373-1378 ◽  
Author(s):  
Jan Hoff ◽  
Øyvind Støren ◽  
Arnstein Finstad ◽  
Eivind Wang ◽  
Jan Helgerud

2018 ◽  
Vol 13 (2) ◽  
pp. 50-54
Author(s):  
Md Abul Kalam Azad ◽  
Md Abul Quashem ◽  
Md Rezaul Karim ◽  
Md Kamrul Hasan

We examined the hypothesis that high blood lactate level in ICU patient after adult cardiac surgery under cardiopulmonary bypass is associated with early adverse outcome. The objective of this study was to evaluate whether blood lactate level after cardiac surgery is predictor of the early outcome after adult cardiac surgery under CPB. In this prospective observational study total 100 patients were enrolled who underwent elective cardiac surgery under CPB as per inclusion and exclusion criteria. Blood lactate levels > 3mmol/ L 6 hours after ICU transfer were present in 57(57%) patients. The binary logistic regression analysis showed that blood lactate level 6 hours after ICU transfer is an independent predictor for prolonged mechanical ventilation time (OR 2.417, 95% CI 1.272 - 4.596, p = .007), prolonged ICU stay (OR 1.562, 95% CI 1.181 - 2.067, p = .002), neurological deficit (OR 2.432, 95% CI 1.539 - 3.843, p = .001), pulmonary complication (OR 1.301, 95% CI 1.011 - 1.676, p = .041), arrhythmia (OR 1.444, 95% CI 1.102 - 1.893, p = .008), renal dysfunction (OR 1.838, 95% CI 1.352 - 2.497, p = .001) and mortality (OR 1.822, 95% CI 1.123- 2.955, p = .015). In conclusion, blood lactate level 6 hours after ICU transfer is an independent risk factor for worse outcomes in adult patients including mortality after cardiac surgery under CPB.University Heart Journal Vol. 13, No. 2, July 2017; 50-54


2017 ◽  
Author(s):  
H. C. Park ◽  
B. K. Lee ◽  
S. J. Lee ◽  
S. Lim

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 190-190
Author(s):  
Seok Shin Tan

Abstract Objectives This study aimed to investigate the association between dietary antioxidant intake and blood lactate level among 20–55 years old Malaysian adults. Methods Subjects (N = 80) of this cross-sectional study were recruited through convenience sampling. Sole Fitness LCB Upright Bike was used to conduct the modified Wingate Anaerobic Test. Dietary antioxidant level was assessed by using Malaysian Adult Nutrition Survey (MANS) 2014 food frequency questionnaire. Short Form International Physical Activity Questionnaire (IPAQ) was used to assess the physical activity level of the subjects. Blood lactate concentration was assessed by The Edge TM blood lactate analyzer, before and after exercise. Saliva samples were collected from subjects for total antioxidant capacity determination using the 2,2-diphenyl-1- picryl-hydrazyl test of saliva (DPPHS) assay. Data was analyzed using SPSS version 25.0. Results The median of total antioxidant intake among Malaysian male and female adults were 1030.64 (734.74) and 9392.90 (10360.44) mg/day, respectively. A significant difference between the means blood lactate level before and after exercise was observed, however, no significant difference in the mean salivary total antioxidant capacity (TAC) before and after exercise. No significant association observed between the total antioxidant intake and salivary TAC before exercise for both males and females, whereas a significant positive moderate association was observed after exercise for females. A significant inverse moderate association between blood lactate level and salivary TAC before exercise was observed among the males in the present study but no association found after exercise for both males and females. Conclusions Present study indicated no significant association between the total dietary antioxidant intake and blood lactate level among Malaysian adults aged 20–55 years old. Future research with larger sample size should develop strategically to confirm these initial findings. Funding Sources International Medical University, Malaysia


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