A Comparison of Oral and Intravenous Sodium Bicarbonate on Urinary pH in Patients at Risk of Contrast-induced Nephropathy: A Pilot Study

Periodontal disease is an infection that, in pregnant women, can act as a risk factor for preterm delivery by increasing local and systemic inflammatory responses. Objective. To analyze the presence of periodontal disease, proinflammatory cytokines, and prostaglandin E2 (PGE2) in pregnant patients at high risk for preterm delivery. Materials and Methods. Pilot study for a case-control study. We included 46 pregnant patients (23 patients at risk of preterm delivery as cases and 23 patients without risk of preterm delivery as controls). We excluded patients who received periodontal treatment, antibiotics, or antimicrobials over the last 3 months as well as those with infections or diseases such as diabetes or hypercholesterolemia. The patients underwent a periodontal assessment, and their levels of cytokines (interleukin- [IL-] 2, IL-6, IL-10, and tumor necrosis factor- [TNF-] α) and prostaglandin E2 (PGE2) were quantified. Results. Patients with periodontal disease showed higher levels of cytokines (IL-2, IL-6, IL-10, and TNF-α) and PGE2. Patients at high risk for preterm birth showed higher IL levels compared with patients at low risk for preterm delivery. PGE2 increased with the severity of periodontal disease. PGE2 was higher in patients at low risk for preterm delivery, although this difference was not significant. Conclusion. Periodontal disease can increase the systemic inflammatory response as well as the levels of PGE2 and inflammatory cytokines in pregnant patients.

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A pilot study of autologous rectus fascial wrap at the time of artificial urinary sphincter placement in patients at risk of cuff erosion

International Urology and Nephrology ◽

10.1007/s11255-020-02380-7 ◽

2020 ◽

Vol 52 (5) ◽

pp. 851-857

Author(s):

J. Gani ◽

D. B. Hennessey ◽

N. Hoag ◽

D. Lee ◽

E. Chung

Keyword(s):

At Risk ◽

Pilot Study ◽

Artificial Urinary Sphincter ◽

Urinary Sphincter ◽

Patients At Risk

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Contrast-Induced Nephropathy: Pathophysiology and Preventive Strategies

Critical Care Nurse ◽

10.4037/ccn2013680 ◽

2013 ◽

Vol 33 (1) ◽

pp. 37-46 ◽

Cited By ~ 42

Author(s):

Ann L. Jorgensen

Keyword(s):

At Risk ◽

Oxygen Free Radicals ◽

Renal Perfusion ◽

Evidence Based ◽

Preventive Strategies ◽

Prevention Strategies ◽

Contrast Induced Nephropathy ◽

Patients At Risk ◽

Flow Through ◽

Hospital Acquired

Contrast-induced nephropathy is the third most common cause of hospital-acquired renal failure, after decreased renal perfusion and nephrotoxic medications. Identification of patients at risk and implementation of preventive strategies can decrease the incidence of this nephropathy. Prevention strategies focus on counteracting vasoconstriction, enhancing blood flow through the nephron, and providing protection against injury by oxygen free radicals. Knowledge of the adverse effects associated with infusion of contrast media, identification of patients at risk for contrast-induced nephropathy, and application of evidence-based prevention strategies allow nurses to assist in the prevention of contrast-induced nephropathy.

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Contrast-induced nephropathy: Definition, epidemiology, and patients at risk

Kidney International ◽

10.1038/sj.ki.5000368 ◽

2006 ◽

Vol 69 ◽

pp. S11-S15 ◽

Cited By ~ 417

Author(s):

R. Mehran ◽

E. Nikolsky

Keyword(s):

At Risk ◽

Contrast Induced Nephropathy ◽

Patients At Risk

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Compartment Syndrome Ultrafiltration Catheters: Report of a Clinical Pilot Study of a Novel Method for Managing Patients at Risk of Compartment Syndrome

Journal of Orthopaedic Trauma ◽

10.1097/bot.0b013e3181f9aba9 ◽

2011 ◽

Vol 25 (6) ◽

pp. 358-365 ◽

Cited By ~ 14

Author(s):

Rick M Odland ◽

Andrew H Schmidt

Keyword(s):

At Risk ◽

Pilot Study ◽

Compartment Syndrome ◽

Patients At Risk ◽

Novel Method

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EARLY DETECTION OF POOR ADHERENCE TO TREATMENT OF PEDIATRIC RHEUMATIC DISEASES: PEDIATRIC RHEUMATOLOGY ADHERENCE QUESTIONNAIRE - A PILOT STUDY

Revista Paulista de Pediatria ◽

10.1590/1984-0462/;2019;37;2;00015 ◽

2019 ◽

Vol 37 (2) ◽

pp. 149-155

Author(s):

Vanessa Bugni Miotto e Silva ◽

Karine Yoshiye Kajiyama Okamoto ◽

Luciana da Silva Ozaki ◽

Claudio Arnaldo Len ◽

Maria Teresa de Sande e Lemos Ramos Ascensão Terreri

Keyword(s):

At Risk ◽

Pilot Study ◽

Early Detection ◽

Medical Treatment ◽

Rheumatic Diseases ◽

Pediatric Rheumatology ◽

Poor Adherence ◽

Adherence To Treatment ◽

Validity And Reliability ◽

Patients At Risk

ABSTRACT Objective: To develop a questionnaire that allows the early detection of patients at risk for poor adherence to medical and non-medical treatment in children and adolescents with chronic rheumatic diseases. Methods: The Pediatric Rheumatology Adherence Questionnaire (PRAQ) was applied in recently diagnosed patients within a period of one to four months after confirmation of the rheumatic disease. After six months, the patients’ adherence to the medical and non-medical treatment was assessed. An internal consistency analysis was conducted to eliminate redundant questions in the PRAQ. Results: A total of 33 patients were included in the pilot study. Six months after the PRAQ had been applied, poor global adherence was observed in seven (21.2%) patients and poor adherence to medical treatment in eight (24.2%) patients. No correlation was observed between the PRAQ scores and the percentages of adherence, as well as the stratification for each index, except for a tendency to a correlation between socioeconomic index and poor adherence to medical treatment (p=0.08). A new PRAQ questionnaire with 25 of the 46 original questions was generated as a result of the reliability analysis. Conclusions: The usefulness of this questionnaire in clinical practice should be still evaluated. Due to the importance of a tool for the early detection of rheumatic patients at risk of poor adherence to treatment, the new PRAQ questionnaire should be reviewed and applied in a larger study to better define its validity and reliability.

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