High Dilution Effects: Physical and Biochemical Basis

Homeopathy ◽  
2005 ◽  
Vol 94 (4) ◽  
pp. 262-263
Author(s):  
Robert T Mathie
2007 ◽  
Vol 14 (5) ◽  
pp. 301-305 ◽  
Author(s):  
Daniele Nani ◽  
Maurizio Brizzi ◽  
Lisa Lazzarato ◽  
Lucietta Betti

Author(s):  
Leoni Villano Bonamin

Background: This review is part of a special issue of journal “Homeopathy” (ELSEVIER) scheduled for publication in 2015, about the follow-up of researches published in the book titled “Ultra-High Dilution, Physiology and Physics”, written and edited by PC Endler and J Schulte in 1994. In this book, Prof. Madeleine Bastide described experimental models in immunology that were used during the 1980s to investigate high dilution effects on several biological systems. Bastide categorized available papers in four categories: high dilutions of antigens; high dilutions of thymus, bursa and other hormones; high dilutions of cytokines and immunopharmacological activity of silica. The studies about high dilutions of antigens were interrupted from this time onwards. Only the in vitro models developed on antigens and histamine dilutions lasted up to 2009. During this process, a huge multi-centre study was performed, with high reproducibility, and involving different independent laboratories. The studies about highly diluted cytokines, thymulin and other hormones brought some regulatory properties of endogenous substances prepared homeopathically, with special focus on epigenetic mechanisms of highly diluted cytokines. The frequently studied substance was Thymulin 5cH, which improved the activity of phagocytes in viral, bacterial and parasitic infections. Studies about the immunopharmacological activity of silica have assumed a new focus: the putative role of silica as active contaminant present in high dilutions, that is still under discussion.


Homeopathy ◽  
2014 ◽  
Vol 103 (1) ◽  
pp. 22-43 ◽  
Author(s):  
Paolo Bellavite ◽  
Marta Marzotto ◽  
Debora Olioso ◽  
Elisabetta Moratti ◽  
Anita Conforti

2021 ◽  
Vol 11 (40) ◽  
pp. 192-193
Author(s):  
Cloe Taddei-Ferretti

Background and Aims. There are several experimental evidences for the effects of high-diluted substances (see e.g. C. Taddei-Ferretti, A. Cotugno 1997, on effects of high-diluted drugs on the prevention and control of mice teratogenicity induced by purine derivatives; N.C. Sukul, C. Taddei-Ferretti, S.P. Sinha Babu, A. De, B. Nandi, A. Sukul, R. Dutta-Nag 2000, on high-diluted Nux vomica countering alcohol-induced loss of righting reflex in toads). Also the physical characterization and mechanism of action of high-diluted drugs have been studied (see e.g. N.C. Sukul, A. Sukul, High dilution effects: Physical and biochemical basis 2004). However, further experimental researches are needed to clarify how physical characteristics of a drug are linked to its global biological effects. Considerations on some high-diluted mineral remedies will be developer here. Methods. In Organon, sect. 119, S. Hahnemann writes: «As certainly each species of plants is different from every other one with regard to external appearance, way of life and growth, taste and smell, and as certainly each mineral, each salt is different from the others with regard to external, internal, physical and chemical qualities [...], so certainly all these vegetal and mineral substances have pathogenetic – and thus also curative – effects different among themselves [...]». This statement may be taken as basis for considering the characteristics of some elements, as ordered in the periodic table, in relation to those of some high-diluted mineral remedies. Conclusions. The elements were previously ordered in the periodic table according to the atomic weight chemically determined, and later more precisely according to the atomic number (number of protons). Then also the electronic configuration was taken into account: properties depending on atomic mass and deep electrons are not periodical, while chemical and several physical properties are linked to external electrons which have periodical configuration. In particular, let us consider the group of elements C, P, S, Cl and the group of elements Ca, Mg, K, Na. One may conclude that the four elements of the first group (respectively receiver-or-donor of 4 electrons, receiver of 3, of 2, of 1 electron), which, according to H. Bernard, are linked to the fixed human constitutions, are close among themselves in the periodic table, while they are very distant from the four elements of the second group (respectively donor of 2, of 2, of 1, of 1 electron), which are close among themselves and are linked to the changing constitutional stages.


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