scholarly journals Effectiveness of a home-based therapeutic exercise program on lower back pain and functionality in Sickle Cell Disease (SCD) patients

Author(s):  
Camila Tatiana Zanoni ◽  
Fábio Galvão ◽  
Renata Manzano Maria ◽  
Roberto Zulli ◽  
Janaina Bosso Ricciardi ◽  
...  
CNS Spectrums ◽  
1999 ◽  
Vol 4 (9) ◽  
pp. 24-31
Author(s):  
David A. Klein ◽  
Daniel P. Greenfield

AbstractChronic benign pain (CBP) can be defined as a type of unpleasant sensory experience that arises from inflammation, visceral stress or damage, or other such pathophysiologic process(es), and that is not associated with a metastatic process. A patient's complaint of pain should be taken seriously by the practitioner, both in terms of the discomfort evoked and the likelihood that the potential cause of the pain requires diagnostic evaluation. This article reviews the diagnosis and treatment of the following common conditions associated with CBP syndromes: fibromyalgia, lower back pain syndrome, sickle-cell disease, reflex sympathetic dystrophy syndrome, and peripheral neuropathies.


PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0250128
Author(s):  
Jonas Alves de Araujo Junior ◽  
Daniele Andreza Antonelli Rossi ◽  
Taina Fabri Carneiro Valadão ◽  
Juliana Cristina Milan-Mattos ◽  
Aparecida Maria Catai ◽  
...  

Background Physical inactivity is an important risk factor for cardiovascular disease. The benefits of exercise in patients with chronic diseases, including cardiovascular diseases, are well established. For patients with sickle cell disease, medical recommendation was to avoid physical exercise for fear of triggering painful crises or increasing the impairment of the cardiopulmonary function. Only recently, studies have shown safety in exercise programs for this population. Despite that, there is no report that assess the effects of physical exercise on cardiac parameters in patients with sickle cell disease. Objective This study aimed to evaluate the impact of regular physical exercise (a home-based program) on cardiovascular function in patients with sickle cell disease. Design A quasi-randomized prospective controlled trial. Setting During the years 2015 and 2016, we started recruiting among adult patients treated at a Brazilian Center for Patients with Sickle Cell Disease to participate in a study involving a home exercise program. The experimental (exercise) and control groups were submitted to clinical evaluation and cardiovascular tests before and after the intervention. Analysis of variance was applied to compare groups, considering time and group factors. Participants Twenty-seven adult outpatients with a sickle cell disease diagnosis. Interventions Exercise group (N = 14): a regular home-based aerobic exercise program, three to five times per week not exceeding give times per week, for eight weeks; no prescription for the control group (N = 13). Main outcome measures Echocardiographic and treadmill test parameters. Results The exercise group showed significant improvement in cardiovascular tests, demonstrated by increased distance traveled on a treadmill (p<0.01), increased ejection fraction (p < 0.01) and improvement of diastolic function assessed by mitral tissue Doppler E’ wave on echocardiography (p = 0.04). None of the patients presented a sickle cell crisis or worsening of symptoms during the exercise program. Conclusion The selected home-based exercise program is safe, feasible, and promotes a favorable impact on functional capacity and cardiovascular function in sickle cell disease patients.


Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4593-4593
Author(s):  
Andrea R Whitfield ◽  
Julie Kanter

Abstract Background: Low back pain is a very common and costly problem that results in significant morbidity. When patients with sickle cell disease (SCD) present with back pain, physicians often assume that their pain is related to an acute painful crisis or to chronic pain caused by bone infarcts in the spinal column resulting in "H" shaped vertebral bodies. The occurrence of vertebral osteonecrosis in SCD patients is a well-documented cause of back pain and is noted on radiographs and often confirmed on magnetic resonance imaging (MRI). However, as with all presentations of pain in persons with SCD, the etiology can also be non-SCD related and should be fully evaluated. This case series profiles six patients with SCD who presented with back pain and underwent further assessment. Methods: We conducted a retrospective chart review of six patients with SCD (mean age of 30.8 years) who presented with back pain during 2014. Institutional review board (IRB) approval was obtained from the Medical University of South Carolina for retrospective chart review. All of the patients were seen in the Comprehensive Lifespan Sickle Cell Clinic for regular evaluation. These patients underwent further evaluation due to presenting symptoms of increased pain, change in quality or character of pain, or associated neuropathic complaints. Results: Three of the patients who presented with neuropathic symptoms were noted to have other (non-SCD) etiologies of back pain (facet cyst, vertebral disc protrusion) as outlined in Table 2. The etiology of the other three patients who presented with increased frequency of baseline pain was secondary to complications of SCD (Table 1). Table 1. Patients with back pain secondary to SCD complications Patient #1 Patient #2 Patient #3 Age 15yo 25yo 31yo Sex Male Female Female Genotype Hgb SS Hgb SS Hgb SS Body Mass Index (BMI) 27 20 27 Presentation Chronic low back pain (increased symptom for patient on chronic transfusion therapy) Increased frequency of low back pain Increased frequency of back pain MRI findings Diffuse decreased signal intensity of the vertebral bodies, related to iron deposition. Osseous sequelae of SCD with Lincoln log morphology. No evidence of significant degenerative changes. Remodeling of the vertebral bodies consistent with patient's known history of sickle cell disease (hyperplastic marrow). Treatment Ferriprox (on study) Opiates, Cymbalta Opiates Table 2. Patients with back pain secondary to other etiologies Patient #4 Patient #5 Patient #6 Age 32yo 36yo 46yo Sex Female Female Female Genotype Hgb SS Hgb SC Hgb SB+ Body Mass Index (BMI) 30 40 Not recorded Presentation New, atypical low back pain, worse with ambulation and upright position Chronic back pain with numbness and tingling in left leg Chronic low back pain and lower extremity tingling MRI findings Mild facet arthropathy at L3-L4 and L4-S1 with small juxta-articular/facet cysts at L3-4 without neuroforaminal or canal narrowing. Right central disc protrusion at L5-S1 with moderate central canal stenosis contacting the right transiting S1 nerve root. Slight interval increase in posterior disc bulge with bilateral paracentral protrusions and mild bilateral facet hypertrophy at L5-S1 causing mild narrowing of left neural foramen. Treatment Facet block and steroid administration with relief Neuropathic pain medication, physical therapy Neuropathic pain medication, referral for steroid injections Discussion: This case series reveals the importance of full evaluation of pain in patients with SCD, especially in those individuals who present with neuropathic or neurologic causes. These cases demonstrate that other etiologies of back pain can be seen and should be treated in patients with SCD. In addition, there is substantial evidence linking obesity (increased BMI) and incidence of low back pain (as also seen in several of these patients). Thus, enhanced primary care, including attention to obesity and diet, is also imperative in this patient population. Disclosures No relevant conflicts of interest to declare.


Author(s):  
Paulius Paškevičius ◽  
Vilma Dudonienė

Background. According to various researchers, lower back pain is experienced by 60-85% of population at least once in a lifetime and up to 94 % in athletes, in addition, back pain is the most common complaint of basketball players. Spinal stabilization exercises, performed in different ways, are most often used in the prevention of sports-related injuries in athletes, but still it remains unclear which is the most effective one.Aim of the study. To determine the effect of different stabilization programs on non-specific lower back pain and functional status of basketball players.Methods. The study was performed with the voluntary consent of subjects. It included 40 subjects who were divided into two groups: first, basketball players (n = 20) who performed spinal stabilization exercises on the mat, and second, basketball players (n = 20) who performed spinal stabilization exercises with functional belts. Subjects’ back pain was assessed on a pain analogy scale (SAS), pain-related function was assessed using the Oswestry Disability Questionnaire, static endurance of basketball players’ trunk muscles was assessed using S. McGill’s tests, and spinal mobility was assessed using the Schober test. All of the measurements were taken pre and post different interventions.Results. A spinal stabilization exercise program without functional belts reduced (p < 0.05) lower back pain and improved (p < 0.05) the functional condition of basketball players. A spinal stabilization exercise program with functional belts reduced (p < 0.05) lower back pain and improved (p < 0.05) functional status. No statistically significant differences were found between the effectiveness of the two stabilization programs used.Conclusion. Spinal stabilization exercises with functional belts and traditional spinal stabilization exercises can be used to reduce back pain, pain-related functional disability in basketball players; however, for greater spinal mobility, it is better to choose exercises with functional belts, and aiming to increase static endurance of trunk muscles it is advisable to use traditional stabilization exercises.Keywords: basketball players, back pain, spinal stability, functional belts.


2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Catherine Hoyt Drazen ◽  
Regina Abel ◽  
Terianne Lindsey ◽  
Allison A King

2014 ◽  
pp. 49
Author(s):  
Mohamed Hendaus ◽  
Samar Osman ◽  
Shabina Khan

2016 ◽  
Vol 63 (9) ◽  
pp. 1578-1585 ◽  
Author(s):  
Steven J. Hardy ◽  
Kristina K. Hardy ◽  
Jeffrey C. Schatz ◽  
Amanda L. Thompson ◽  
Emily R. Meier

2004 ◽  
Vol 4 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Emela Mujić Skikić ◽  
Suad Trebinjac ◽  
Dijana Avdić ◽  
Slavica Čakota

This study encompassed 64 participants with symptoms of low back pain, 33 in McKenzie group and 31 in Brunkow group. Patients attended exercise program daily and they were asked to do the same exercise at home--five times a day in series of 5 to 10 repetition each time, depending of stage of disease and pain intensity. All patients were assessed for the spinal motion, before and after the treatment. All parameters for spinal movements showed improvement after exercising McKenzie program for lower back pain with a significant difference of p<0.01 for all motions. Also, in Brunkow group, all of the parameters showed statistically significant improvement at the end of treatment in relation to pre-treatment values, with significant difference of p<0.01 for all motions. Statistically comparison between McKenzie and Brunkow difference in score at the end of the treatment showed statistically significant improvement in McKenzie group, for extension, right and left side flexion, while flexion score didn't show statistically significant difference. McKenzie exercises seemed to be more effective than Brunkow exercises for improvement in spinal motion. Both, McKenzie and Brunkow exercises can be used for spinal mobility improvement in patients with lower back pain, but is preferable to use McKenzie exercises first, to decrease the pain and increase spinal mobility, and then Brunkow exercises to strengthen the paravertebral muscles.


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