Mitochondrial estrogen receptor β2 drives antiapoptotic pathways in advanced serous ovarian cancer

2015 ◽  
Vol 46 (8) ◽  
pp. 1138-1146 ◽  
Author(s):  
Alessandra Ciucci ◽  
Gian Franco Zannoni ◽  
Daniele Travaglia ◽  
Giovanni Scambia ◽  
Daniela Gallo
2011 ◽  
Vol 122 (3) ◽  
pp. 573-579 ◽  
Author(s):  
Ilaria De Stefano ◽  
Gian Franco Zannoni ◽  
Maria Grazia Prisco ◽  
Anna Fagotti ◽  
Lucia Tortorella ◽  
...  

2014 ◽  
Vol 132 (2) ◽  
pp. 351-359 ◽  
Author(s):  
Alessandra Ciucci ◽  
Gian Franco Zannoni ◽  
Daniele Travaglia ◽  
Marco Petrillo ◽  
Giovanni Scambia ◽  
...  

2013 ◽  
Author(s):  
Sophia Hl George ◽  
Anca Milea ◽  
Ramlogan Sowamber ◽  
Danielle Toccalino ◽  
Patricia A. Shaw

2019 ◽  
pp. 92-95
Author(s):  
D.G. Sumtsov ◽  
◽  
M.L. Kusyomenska ◽  
G.A. Sumtsov ◽  
◽  
...  

In the literature review the authors present an analysis of the current stateproblem of ovarian cancer and ways of its possible solution. According to clinicalobservations and conducted in recent decades by morphological,immunohistochemical and molecular genetic studies it is fairly proved that theprimary cause of serous ovarian cancer is the pathology of the mucous layer offallopian tube. In the fallopian tube as a result of ciculation of inflammation andcarcinogens elements arises dysplasia of the mucosa with the development of thepreinvasive and initial invasive carcinoma with subsequent damage of the ovariesand pelvic peritoneum. Retrospective studies of a significant number of women’shealth status who had a deligation or removal of fallopian tubes in previous years showed a decrease in the disease incidence of serous ovarian cancer from 30 to 90%. The conclusions about the possibility of preventive measures of ovariancancer by opportunistic salpingectomy at post-productive age are made. In many world countries (Canada, China, France, Italy, Austria) the introduction of such a method of prevention has been started. We believe that in Ukraine there is an urgent need and all possibilities to solve this problem. Key words: ovarian cancer, preventive measures, opportunistic salpingectomy.


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