DNA binding, protein interaction, radical scavenging and cytotoxic activity of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde(2′-hydroxybenzoyl)hydrazone and its Cu(II) complexes: A structure activity relationship study

2012 ◽  
Vol 385 ◽  
pp. 81-93 ◽  
Author(s):  
Duraisamy Senthil Raja ◽  
Nattamai S.P. Bhuvanesh ◽  
Karuppannan Natarajan
Keyword(s):  
Dna Binding ◽  
Cytotoxic Activity ◽  
Protein Interaction ◽  
Binding Protein ◽  
Radical Scavenging ◽  
Dna Binding Protein ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

scholarly journals Ni(ii) and Co(ii) complexes of an asymmetrical aroylhydrazone: synthesis, molecular structures, DNA binding, protein interaction, radical scavenging and cytotoxic activity

RSC Advances ◽  
2017 ◽  
Vol 7 (66) ◽  
pp. 41527-41539 ◽  
Author(s):  
Yueqin Li ◽  
Zhiwei Yang ◽  
Minya Zhou ◽  
Yun Li ◽  
Jing He ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cytotoxic Activity ◽  
Cancer Cells ◽  
Protein Interaction ◽  
Binding Protein ◽  
Radical Scavenging ◽  
Dna Binding Protein ◽  
Molecular Structures ◽  
Bsa Binding ◽  
Apoptosis In Cancer Cells

The DNA/BSA binding, antioxidant and cytotoxic activity of Ni(ii) and Co(ii) complexes bearing aroylhydrazone were investigated to induce apoptosis in cancer cells.

scholarly journals Synthesis and Structure–Activity Relationship Study of Triazine-Based Inhibitors of the DNA Binding of NF-κB

2014 ◽  
Vol 62 (7) ◽  
pp. 700-708 ◽  
Author(s):  
Shinya Fujii ◽  
Takanobu Kobayashi ◽  
Aki Nakatsu ◽  
Hiroshi Miyazawa ◽  
Hiroyuki Kagechika
Keyword(s):  
Dna Binding ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

Evaluation of DNA Binding, Protein Interaction, and Cytotoxic Activity of a Mononuclear Copper(II) Complex

2013 ◽  
Vol 640 (7) ◽  
pp. 1506-1513 ◽  
Author(s):  
Zhanfen Chen ◽  
Jian Zhang ◽  
Pan Zeng ◽  
Shuping Zhang ◽  
Chuanmin Jin
Keyword(s):  
Dna Binding ◽  
Cytotoxic Activity ◽  
Protein Interaction ◽  
Binding Protein ◽  
Dna Binding Protein

Distinct supramolecular assemblies of Fe(iii) and Ni(ii) complexes constructed from the o-vanillin salicylhydrazone ligand: syntheses, crystal structures, DNA/protein interaction, and antioxidant and cytotoxic activity

2019 ◽  
Vol 43 (21) ◽  
pp. 8024-8043 ◽  
Author(s):  
Yueqin Li ◽  
Yun Li ◽  
Zhiwei Yang ◽  
Fantao Meng ◽  
Nana Wang ◽  
...  
Keyword(s):  
Dna Binding ◽  
Coordination Polymer ◽  
Cytotoxic Activity ◽  
Crystal Structures ◽  
Protein Interaction ◽  
Radical Scavenging ◽  
Dna Binding Protein ◽  
Anticancer Properties ◽  
Dna Protein Interaction

A novel aroylhydrazone ligand-bridged Ni(ii) coordination polymer was reported and its DNA binding, protein interaction, radical scavenging and in vitro anticancer properties were evaluated.

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