scholarly journals Native Joint Septic Arthritis due to Kingella kingae in an Adult

IDCases ◽  
2021 ◽  
pp. e01106
Author(s):  
Benjamin Chen ◽  
Takaaki Kobayashi ◽  
Hasan Samra ◽  
Poorani Sekar
2016 ◽  
Vol 102 (7) ◽  
pp. 959-961 ◽  
Author(s):  
M. Le Hanneur ◽  
C. Vidal ◽  
C. Mallet ◽  
K. Mazda ◽  
B. Ilharreborde

2021 ◽  
Vol 10 (1) ◽  
pp. 25
Author(s):  
Giacomo DeMarco ◽  
Moez Chargui ◽  
Benoit Coulin ◽  
Benoit Borner ◽  
Christina Steiger ◽  
...  

Nowadays, Kingella kingae (K. kingae) is considered as the main bacterial cause of osteoarticular infections (OAI) in children aged less than 48 months. Next to classical acute hematogenous osteomyelitis and septic arthritis, invasive K. kingae infections can also give rise to atypical osteoarticular infections, such as cellulitis, pyomyositis, bursitis, or tendon sheath infections. Clinically, K. kingae OAI are usually characterized by a mild clinical presentation and by a modest biologic inflammatory response to infection. Most of the time, children with skeletal system infections due to K. kingae would not require invasive surgical procedures, except maybe for excluding pyogenic germs’ implication. In addition, K. kingae’s OAI respond well even to short antibiotics treatments, and, therefore, the management of these infections requires only short hospitalization, and most of the patients can then be treated safely as outpatients.


2021 ◽  
Vol 103-B (3) ◽  
pp. 584-588
Author(s):  
Mohammed Khattak ◽  
Sujith Vellathussery Chakkalakumbil ◽  
Robert A. Stevenson ◽  
David J. Bryson ◽  
Michael J. Reidy ◽  
...  

Aims The aim of this study was to determine the extent to which patient demographics, clinical presentation, and blood parameters vary in Kingella kingae septic arthritis when compared with those of other organisms, and whether this difference needs to be considered when assessing children in whom a diagnosis of septic arthritis is suspected. Methods A prospective case series was undertaken at a single UK paediatric institution between October 2012 and November 2018 of all patients referred with suspected septic arthritis. We recorded the clinical, biochemical, and microbiological findings in all patients. Results A total of 160 patients underwent arthrotomy for a presumed septic arthritis. Of these, no organism was identified in 61 and only 25 of these were both culture- and polymerase chain reaction (PCR)-negative. A total of 36 patients did not undergo PCR analysis. Of the remaining 99 culture- and PCR-positive patients, K. kingae was the most commonly isolated organism (42%, n = 42). The knee (n = 21), shoulder (n = 9), and hip (n = 5) were the three most commonly affected joints. A total of 28 cases (66%) of K. kingae infection were detected only on PCR. The mean age of K. kingae-positive cases (16.1 months) was significantly lower than that of those whose septic arthitis was due to other organisms (49.4 months; p < 0.001). The mean CRP was significantly lower in the K. kingae group than in the other organism group (p < 0.001). The mean ESR/CRP ratio was significantly higher in K. kingae (2.84) than in other infections (1.55; p < 0.008). The mean ESR and ESR/CRP were not significantly different from those in the 'no organism identified' group. Conclusion K. kingae was the most commonly isolated organism from paediatric culture- and/or PCR-positive confirmed septic arthritis, with only one third of cases detected on routine cultures. It is important to develop and maintain a clinical suspicion for K. kingae infection in young patients presenting atypically. Routine PCR testing is recommended in these patients. Cite this article: Bone Joint J 2021;103-B(3):584–588.


PEDIATRICS ◽  
1993 ◽  
Vol 92 (6) ◽  
pp. 800-804
Author(s):  
Pablo Yagupsky ◽  
Ron Dagan ◽  
Charles B. Howard ◽  
Menachem Einhorn ◽  
Imad Kassis ◽  
...  

Objective. To characterize the clinical spectrum and epidemiology of invasive Kingella kingae infections in children living in southern Israel. Design. Five-year observational, descriptive study. Population. Children in whom K. kingae was isolated from blood or other normally sterile body fluid. Results. Twenty-five patients with invasive K. kingae infection (13 male and 12 female) were identified. Twenty-four of these children were younger than 2 years. The annual incidence was 14.3, 27.4, and 31.9 cases per 100 000 children ≤4 years, ≤24 months, and ≤12 months, respectively. Seventeen (68%) of 25 patients sought treatment between July and December. Concomitant upper respiratory tract infection or stomatitis was observed in 14 (56%) of the patients, suggesting a respiratory or buccal source for the infection. Four children were bacteremic: 2 of them suffered from a lower respiratory tract infection, and the remaining 2 had bacteremia with no evident focal infection. Twenty-one children had skeletal infections and none of them was bacteremic; 16 had septic arthritis, 3 had osteomyelitis, 1 had both osteomyelitis and septic arthritis of the adjacent joint, and 1 had dactylitis of the hand. Involvement of the ankle was unusually frequent among children with septic arthritis, whereas the calcaneus was involved in 3 of the 4 children with osteomyelitis. Antibiotic treatment resulted in full recovery in all cases, and only 2 patients with septic arthritis required surgical drainage. Conclusion. Kingella kingae is a much more common cause of invasive infection in young children than has been previously recognized. The disease has a clear seasonal pattern, usually affects the skeletal system, frequently involves unusual bones and joints, and follows a benign course.


1992 ◽  
Vol 30 (5) ◽  
pp. 1278-1281 ◽  
Author(s):  
P Yagupsky ◽  
R Dagan ◽  
C W Howard ◽  
M Einhorn ◽  
I Kassis ◽  
...  

2019 ◽  
Vol 38 (10) ◽  
pp. e270-e271
Author(s):  
Anais Chosidow ◽  
Stéphane Bonacorsi ◽  
Didier Moissenet ◽  
Philippe Bidet ◽  
Aurélie Schnuriger ◽  
...  

2014 ◽  
Vol 165 (5) ◽  
pp. 985-989.e1 ◽  
Author(s):  
Pablo Yagupsky ◽  
Gal Dubnov-Raz ◽  
Amadeu Gené ◽  
Moshe Ephros

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