Novel hyaluronic acid coated hydrophobically modified chitosan polyelectrolyte complex for the delivery of doxorubicin

2019 ◽  
Vol 126 ◽  
pp. 254-261 ◽  
Author(s):  
Lili Chen ◽  
Yuanyuan Zheng ◽  
Longbao Feng ◽  
Zonghua Liu ◽  
Rui Guo ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Polyelectrolyte Complex ◽  
Modified Chitosan ◽  
Hydrophobically Modified

Novel alginate coated hydrophobically modified chitosan polyelectrolyte complex for the delivery of BSA

2013 ◽  
Vol 24 (9) ◽  
pp. 2093-2100 ◽  
Author(s):  
Rui Guo ◽  
Lili Chen ◽  
Shushan Cai ◽  
Zonghua Liu ◽  
Yi Zhu ◽  
...  
Keyword(s):  
Polyelectrolyte Complex ◽  
Modified Chitosan ◽  
Hydrophobically Modified

scholarly journals Antibacterial Activity of N,O-Acylated Chitosan Derivative

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 107
Author(s):  
Agnieszka Piegat ◽  
Anna Żywicka ◽  
Agata Niemczyk ◽  
Agata Goszczyńska
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Chitosan Derivative ◽  
Modified Chitosan ◽  
Microdilution Method ◽  
Hydrophobically Modified ◽  
Mechanism Of Interaction ◽  
H Pylori ◽  
Living Bacteria ◽  
Antibacterial Potential

The antibacterial activity of N,O-acylated chitosan derivative with linoleic acid (CH_LA) was tested by disc and well diffusion, agar impregnation and microdilution methods against Staphylococcus aureus, Escherichia coli and Helicobacter pylori strains. Hydrophobically modified chitosan (HMC) was expected to exhibit enhanced antibacterial activity and specific mucin interactions. Although diffusion tests have not indicated the antibacterial potential of chitosan (CH) or CH_LA, the results of the microdilution method demonstrated that tested polymers significantly reduced the amount of living bacteria cells in different concentrations depending on the microorganism. Additionally, CH_LA was characterized by enhanced antibacterial activity compared to CH, which may suggest a different mechanism of interaction with S. aureus and H. pylori. Furthermore, the UV-VIS analysis revealed that the amphiphilic character of derivative led to strong CH_LA–mucin interactions. The study proved the high potential of CH_LA in antibacterial applications, especially for the gastrointestinal tract.

Self-assembly of hydrophobically modified hyaluronic acid

2021 ◽  
Vol 546 ◽  
pp. 149161
Author(s):  
Frantisek Ondreas ◽  
Marcela Dusankova ◽  
Jaroslav Sita ◽  
Martin Cepa ◽  
Jiri Stepan ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Self Assembly ◽  
Hydrophobically Modified

scholarly journals Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery

2018 ◽  
Vol Volume 13 ◽  
pp. 5837-5848 ◽  
Author(s):  
M Gulrez Zariwala ◽  
Harshada Bendre ◽  
Anatoliy Markiv ◽  
Sebastien Farnaud ◽  
Derek Renshaw ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Modified Chitosan ◽  
Hydrophobically Modified

Injectable hydrogel composed of hydrophobically modified chitosan/oxidized-dextran for wound healing

2019 ◽  
Vol 104 ◽  
pp. 109930 ◽  
Author(s):  
Xinchen Du ◽  
Yujie Liu ◽  
Xin Wang ◽  
Hongyu Yan ◽  
Lina Wang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Injectable Hydrogel ◽  
Oxidized Dextran ◽  
Modified Chitosan ◽  
Hydrophobically Modified

Complex Coacervates between a Lactose-Modified Chitosan and Hyaluronic Acid as Radical-Scavenging Drug Carriers

2018 ◽  
Vol 19 (10) ◽  
pp. 3936-3944 ◽  
Author(s):  
Federica Vecchies ◽  
Pasquale Sacco ◽  
Eva Decleva ◽  
Renzo Menegazzi ◽  
Davide Porrelli ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Radical Scavenging ◽  
Drug Carriers ◽  
Modified Chitosan
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