Erythropoietin, as a biological macromolecule in modification of tissue engineered constructs: A review

2021 ◽  
Author(s):  
Xiao-yu Wu ◽  
Yi-miao Zhu ◽  
Yang Qi ◽  
Wen-Wen Xu ◽  
Jing-Zhai
Keyword(s):  
Biological Macromolecule

scholarly journals Biochemistry: one molecule at a time

2021 ◽  
Vol 65 (1) ◽  
pp. 1-3
Author(s):  
Dominika T. Gruszka
Keyword(s):  
Complex Networks ◽  
Single Molecule ◽  
Population Level ◽  
Early Career ◽  
Molecular Heterogeneity ◽  
Biological Processes ◽  
Biological Macromolecule ◽  
Exciting Field ◽  
Early Career Researchers ◽  
Mechanistic Basis

Abstract Biological processes are orchestrated by complex networks of molecules. Conventional approaches for studying the action of biomolecules operate on a population level, averaging out any inhomogeneities within the ensemble. Investigating one biological macromolecule at a time allows researchers to directly probe individual behaviours, and thus characterise the intrinsic molecular heterogeneity of the system. Single-molecule methods have unravelled unexpected modes of action for many seemingly well-characterised biomolecules and often proved instrumental in understanding the intricate mechanistic basis of biological processes. This collection of reviews aims to showcase how single-molecule techniques can be used to address important biological questions and to inspire biochemists to ‘zoom in’ to the population and probe individual molecular behaviours, beyond the ensemble average. Furthermore, this issue of Essays in Biochemistry is the very first written and edited entirely by early career researchers, and so it also highlights the strength, diversity and excellence of the younger generation single-molecule scientists who drive this exciting field of research forward.

The Biological Macromolecule Crystallization Database

2006 ◽  
pp. 669-674
Author(s):  
G. L. Gilliland ◽  
M. Tung ◽  
J. E. Ladner
Keyword(s):  
Biological Macromolecule

scholarly journals Choosing the Method of Crystallization to Obtain Optimal Results

Crystals ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 106 ◽  
Author(s):  
Lata Govada ◽  
Naomi Chayen
Keyword(s):  
Phase Separation ◽  
Biological Macromolecule ◽  
Amorphous Precipitate

Anyone who has ever attempted to crystallise a protein or other biological macromolecule has encountered at least one, if not all of the following scenarios: No crystals at all, tiny low quality crystals; phase separation; amorphous precipitate and the most frustrating; large, beautiful crystals that do not diffract at all. In this paper we review a number of simple ways to overcome such problems, which have worked well in our hands and in other laboratories. It brings together information that has been dispersed in various publications and lectures over the years and includes further information that has not been previously published.

Development of emulgels formulated with sweet fennel oil and rhamsan gum, a biological macromolecule produced by Sphingomonas

2019 ◽  
Vol 129 ◽  
pp. 326-332 ◽  
Author(s):  
Luis A. Báez ◽  
Jenifer Santos ◽  
Pablo Ramírez ◽  
Luis A. Trujillo-Cayado ◽  
José Muñoz
Keyword(s):  
Biological Macromolecule ◽  
Rhamsan Gum ◽  
Fennel Oil

scholarly journals Biological macromolecule chitosan grafted co-polymeric composite: bio-adsorption probe on cationic dyes

2021 ◽  
Author(s):  
Shyam R. Khairkar ◽  
Shubham V. Pansare ◽  
Amol A. Shedge ◽  
Shraddha Chhatre ◽  
Dnyaneshwar K. Kulal ◽  
...  
Keyword(s):  
Monomer Concentration ◽  
Polymeric Composite ◽  
Sorption Process ◽  
Vinyl Monomer ◽  
Grafted Polymers ◽  
Biological Macromolecule ◽  
Buffer Solution ◽  
Toxic Dyes ◽  
Ph Buffer Solution ◽  
Ph Buffer

AbstractChitosan biological macromolecule is a versatile polymer; chemical modification has been carried out that lead to the formation of chitosan grafted polymers composites (Chito-g-PC). We proposed synthesis of six various Chito-g-PC as sorbents for toxic dyes. A novel graft copolymerization method based on radical polymerization with vinyl monomer like acrylic acid, acrylamide, N-isopropylacrylamide, methacrylic acid and polyacrylonitrile were utilized in order to address the large amount of swelling at four different pH buffers solution. The effect of initiator and monomer concentration, time and temperature on % grafting and % grafting efficiency were performed. Comparative characterization of Chito and Chito-g-PC were evaluated by SEM, XRD and FTIR, as well as solubility characteristics of the composites were determined by various pH buffer solution. Cationic toxic dyes Malachite green (MG) and Methylene blue (MB) were selected as the sorbet, and Chito-g-PC were used as biosorbents. Thermodynamic analysis showed that the sorption process was spontaneous and endothermic with an increased randomness. The sorption experiments were realized with six different Chito-g-PC for MG and MB at various pH.

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