Antibiotic susceptibility pattern of genital tract bacteria in pregnant women with preterm premature rupture of membranes in a resource-limited setting

2014 ◽  
Vol 127 (1) ◽  
pp. 10-14 ◽  
Author(s):  
George U. Eleje ◽  
Joseph I. Adinma ◽  
Samuel Ghasi ◽  
Joseph I. Ikechebelu ◽  
Anthony O. Igwegbe ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Antibiotic Susceptibility ◽  
Genital Tract ◽  
Susceptibility Pattern ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Antibiotic Susceptibility Pattern ◽  
Preterm Premature Rupture ◽  
Resource Limited ◽  
Limited Setting

450: Transplacental transfer of ceftriaxone in pregnant women with preterm premature rupture of membranes

2020 ◽  
Vol 222 (1) ◽  
pp. S295-S296
Author(s):  
Young Mi Jung ◽  
Seung Mi Lee ◽  
Jae Seong Oh ◽  
Seo Hyun Yoon ◽  
Joo-Youn Cho ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Transplacental Transfer ◽  
Preterm Premature Rupture

scholarly journals Antibiotic susceptibility pattern of group B streptococcal isolates from maternal genital tract

2019 ◽  
Vol 8 (7) ◽  
pp. 2738
Author(s):  
Vijayan Sharmila ◽  
Thirunavukkarasu Arun Babu
Keyword(s):  
Pregnant Women ◽  
Antibiotic Susceptibility ◽  
Group B Streptococcus ◽  
Antibiotic Sensitivity ◽  
Developed Countries ◽  
Susceptibility Pattern ◽  
Antibiotic Susceptibility Pattern ◽  
Sensitivity Pattern ◽  
Prevention And Treatment ◽  
Group B

Background: Group B streptococcus (GBS) is one of the important cause of early onset neonatal sepsis in developed countries leading to increased neonatal morbidity and mortality. Penicillin and Ampicillin are the drugs of choice for prevention of GBS infections. Antibiotic resistance amongst GBS isolates is an emerging health problem affecting neonates. Hence, this study was performed to determine the antibiotic susceptibility pattern of Group B Streptococcus (GBS) in a population of pregnant women.Methods: A prospective study was done to screen pregnant women for vaginal and rectal GBS colonization during their regular visits to antenatal clinic. Todd-Hewitt broth, an enrichment medium for GBS was used for isolation. The antibiotic susceptibility pattern of the isolates were studied.  Results: A total of 300 pregnant women were screened for GBS colonization. GBS colonization rate in our study was 2.3%. The antibiotic susceptibility pattern of the isolates revealed that none of the isolates were resistant to penicillin or clindamycin, while resistance was noted to erythromycin (14.3%) and   tetracycline (71.4%).Conclusions: GBS continues to remain sensitive to Penicillin which is the drug of choice for prevention and treatment of GBS.  Consistent surveillance of antibiotic sensitivity pattern of GBS as well as for other organisms implicated in new born sepsis and maternal infections is required to formulate guidelines for prevention and treatment.

scholarly journals Risk Factors and Outcomes of Preterm Premature Rupture of Membranes in a Cohort of 6968 Pregnant Women Prospectively Recruited

2019 ◽  
Vol 8 (11) ◽  
pp. 1987 ◽  
Author(s):  
Damien Bouvier ◽  
Jean-Claude Forest ◽  
Loïc Blanchon ◽  
Emmanuel Bujold ◽  
Bruno Pereira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Regression Analyses ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Level Of Education ◽  
Preterm Premature Rupture ◽  
History Of

We revisited risk factors and outcomes related to the preterm premature rupture of membranes (PPROM). A total of 7866 pregnant women were recruited during 5 years at their first prenatal visit to the perinatal clinic of the institution. We compared three groups (women without prematurity, women with spontaneous preterm labor with intact membranes (sPL with IM), women with PPROM) regarding 60 criteria about characteristics, lifestyle, medical, gynecological, obstetrical history of mothers, medication during pregnancy, events at delivery, and complications in neonates. Logistic regression analyses adjusting for potential confounding factors were used. Of the 6968 women selected, 189 (2.8%) presented a PPROM, and 225 (3.2%) an sPL with IM. The specific risk factors for PPROM were body mass index (BMI) <18.5 kg/m2 (adjusted odds ratio, aOR: 2.00 (1.09–3.67)), history of PPROM (aOR: 2.75 (1.19–6.36)), nulliparity (aOR: 2.52 (1.77–3.60)), gestational diabetes (aOR: 1.87 (1.16–2.99)), and low level of education (aOR: 2.39 (1.20–4.78)). The complications associated with PPROM were abruption placentae, cesarean, APGAR 5′ <4, birth weight <2500 g, stillbirth, neonatal jaundice, and hospitalization of mother and neonates. All these complications were also associated with sPL with IM. Our study confirms some of the risk factors of PPROM and highlights a new one: gestational diabetes. Outcomes of PPROM are related to prematurity.

Management of born too soon preterm birth complicated by preterm premature rupture of membranes

2016 ◽  
pp. 58-64
Author(s):  
O.B. Malanchuk ◽  
◽  
V.P. Lakatosh ◽  
O.U. Kostenko ◽  
M.I. Antonuk ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Statistical Analysis ◽  
Pregnant Women ◽  
Neonatal Mortality ◽  
Perinatal Complications ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Mortality And Morbidity ◽  
Pregnancy And Childbirth ◽  
Preterm Premature Rupture

In Ukraine, each year born about 1,000 children ELBW, representing 0.3% of all newborns. The survival of infants with ELBW in our country has a slow upward trend and does not exceed 50%. Infants with ELBW have the highest risk of death and are the group most at risk for the development of chronic diseases of the respiratory and nervous systems and sensory apparatus and associated disability. Considering the growth of the number of children at private ELBW on the background PPROM, high perinatal morbidity and infant mortality, reduced health and reproductive capacity of women becoming urgency tactics of pregnancy and labor with premature rupture of membranes. The objective: perynatalniyh reduce complications in terms of 22-28 weeks of pregnancy complicated by premature rupture of membranes based on developing the tactics of pregnancy and childbirth. Patients and methods. To reduce perinatal complications analyzed the effect of different methods of pregnancy and childbirth on the state of newborns in gestational age 22-28 weeks against the backdrop of premature discharge of amniotic fluid. The control group consisted of 56 women who had less than a day anhydrous term. In the study group applied expectant tactics of anhydrous long term. Depending on the length of the term of anhydrous main group was divided into 2 subgroups. Sub-IA amounted to 86 pregnant women with anhydrous period of 5 days, and IP subgroup totaled 64 pregnant women with anhydrous period of 25 days. Statistical analysis of the results was performed using Microsoft Excel. Probability difference calculated by Student’s t-criterion. Results. Аnalyzing the structure and frequency of obstetric and perinatal complications in women in the period 22-28 weeks of pregnancy with different duration waterless terms, different terms of delivery proved the effectiveness of the tactics of delivery, which is used in perinatal centers m. Kyiv. This correlates with clinical data - statistical analysis of indicators of neonatal mortality and morbidity. Conclusion. Оf the research found that the rates of neonatal mortality and morbidity affecting: duration of anhydrous interval, gestational period, methods of delivery. Long expectant tactics leads to a real reduction of RDS, but an increase in the incidence of chorioamnionitis and neonatal infection. Therefore, wait-recommended tactics for 5 days, followed by delivery of women. At 22-27 weeks of pregnancy delivery path has no impact on rates of neonatal morbidity. The advantage in the delivery of women in the period 27-28 weeks, especially in the immature cervix and pelvic peredlezhenni fetal provided cesarean section. Key words: born too soon preterm birth, preterm premature rupture of membranes, pregnancy, method of delivery, birth with extremely low body weight.

Sign in / Sign up

Export Citation Format

Share Document