Geographic disparities in pneumonia-specific under-five mortality rates in Mainland China from 1996 to 2015: a population-based study

OBJECTIVE: To assess the impact of asthma on Canadian mortality rates over a 45-year period.DESIGN: A descriptive, population-based study.SETTING: Canada.SUBJECTS: All persons who died from asthma in Canada from 1946 to 1990 as reported to Statistics Canada in Ottawa.MAIN OUTCOME MEASURES: Standardized mortality ratios, age-specific patterns of death, potential years of life lost (PYLL) and life expectancy lost.RESULTS: A total of 12,010 male and 8486 female asthma deaths were recorded in Canada from 1946 to 1990. Mortality rates for both sexes declined from a high of between three to six deaths in 1951 to 1955 to approximately two deaths per 100,000 in 1986 to 1990, with the decline in rates being greater for males than females. Age-specific mortality rates were highest al all ages in 1951 to 1955, except for 15 to 24 years when deaths rates for the 1981 to 1985 period were greater. PYLL exhibit the same pattern as mortality, peaking in 1951 to 1955 and subsequently declining with each period. Loss in life expectancy due to asthma was about one month (not significant) in all time periods.CONCLUSIONS: Asthma mortality rates have declined significantly over the study period. This decline appears to be linked with the convergence of sex-specific rates and with changes in the patterning or age-specific mortality. The impact of asthma on the life expectancy of Canadians is small.

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The Prevalence of Digestive Tract Defects in China: A Population-Based Study

10.21203/rs.3.rs-132228/v1 ◽

2020 ◽

Author(s):

Fangfang Song ◽

Jie Chen ◽

Wei Cai

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Digestive Tract ◽

Congenital Heart ◽

Mainland China ◽

Population Based ◽

Categorical Variables ◽

Congenital Defects ◽

Population Based Study ◽

Congenital Diseases

Abstract Objectives: The prevalence of congenital digestive tract defects among Chinese people is rarely reported. The aim of this study was to investigate the incidence of digestive tract defects in mainland China and reported the clinical outcomes of these cases. Methods: This research describes a local population-based study of registered births in Jiaxing, China from January 2015 to December 2019. Prevalence estimates (per 10,000 births) of digestive tract malformations were calculated. We used the χ2 test to compare the differences between categorical variables. Results: In this study a total of 76 cases of digestive tract malformations were included. We calculated the following incidence rates per 10,000 births: 1.65 for esophageal atresia; 1.24 for congenital defects of gastric musculature; 2.33 for hypertrophic pyloric stenosis; 3.72 for duodenal and intestinal atresia; 2.25 for congenital malrotation of intestine; 1.45 for Hirschsprung’s disease; 4.75 for anal atresia/stricture; and 1.40 for biliary atresia. There were 31 cases (40.8%) of low birth weight (<2500g), 28 cases (36.8%) were premature births (<37 weeks), and 25 cases (32.9%) had concomitant congenital heart disease. Conclusions: This study estimated the incidence of digestive tract malformations, and the findings may provide a foundation for future epidemiologic studies of these congenital diseases in mainland China. In addition, we found that roughly one third of our subjects with digestive tract defects also had concomitant congenital heart disease, suggesting a link between the two which may warrant further investigation. Moreover, our data will also be helpful in determining the resources needed for basic and public health research into digestive tract malformation in China.

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