Characterization and mosquito repellent activity of citronella oil nanoemulsion

2009 ◽  
Vol 372 (1-2) ◽  
pp. 105-111 ◽  
Author(s):  
Usawadee Sakulku ◽  
Onanong Nuchuchua ◽  
Napaporn Uawongyart ◽  
Satit Puttipipatkhachorn ◽  
Apinan Soottitantawat ◽  
...  
2020 ◽  
Vol 5 (3) ◽  
pp. 214-223
Author(s):  
Pooja Dubey ◽  
Pravin Shende

Objectives: Citronella oil is considered one of the effective mosquito- repellent oil and in cooperation of oil into nanosponges will help to prevent its evaporation and enhance its effect. Objective: The objective of the current research was to formulate and characterize CDI cross-linked nanosponges of citronella oil for controlled mosquito-repellent activity. Method: β-cyclodextrin-based nanosponges were prepared by polymer condensation method and encapsulated with citronella oil by the sonication method. A topical cream containing citronella oil-based nanosponges was formulated by the phase inversion temperature method. Particle size, zeta potential, encapsulation efficiency, stability, in vitro release, FTIR and DSC studies were used as characterization parameters. Results: The particle size of citronella oil encapsulated β-cyclodextrin-based nanosponges was 23.05±3.88 nm. The zeta potential of nanosponges was sufficiently high to prevent aggregation. In vitro studies revealed the controlled release of citronella oil from the nanosponges for 24 h. FTIR and DSC confirmed the interaction of the citronella oil with the nanosponges. Conclusion: Citronella oil encapsulated nanosponges in the topical formulation is an alternative to synthetic marketed creams for controlled mosquito-repellent activity.


2011 ◽  
Vol 9 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Mahesh Pal ◽  
Anil Kumar ◽  
Krishna Tewari

The chemical composition of the essential oil obtained from the leaves of Plectranthus incanus Link, with the yield of 0.6% (w/v), was analyzed by GC and GC/MS. A total of 16 constituents, representing 95.2% of the oil, were identified. The major components of the oil were fenchone (6.0%), piperitone oxide (32.4%), piperitenone (3.0%) and piperitenone oxide (41.5%). The repellent activity of the volatile oil at different concentrations was measured by the protection period against the bites of Anopheles stephensi and Culex fatigans. The tested oil had stronger repellent activity than citronella oil, which was used as a positive control. LC50 (30 min) for P. incanus oil against An. stephensi and C. fatigans were 23.8 and 19.6 ?l/L air, respectively, whereas LC50 of citronella oil were 31.7 and 31.0 ?l/L air. Thus, P. incanus may be regarded as a potential valuable source of chemicals that have strong mosquito repellent activity, and could be used for the preparation of mosquito repellent formulations.


2020 ◽  
Vol 2020 ◽  
pp. 1-5 ◽  
Author(s):  
Willy Tirza Eden ◽  
Dante Alighiri ◽  
Kasmadi Imam Supardi ◽  
Edy Cahyono

This study examines the active component of Cymbopogon winterianus (Java citronella) oil, as a green mosquito repellent, obtained through a steam distillation method. Java citronella oil, which contains citronellol, citronellal, and geraniol, was isolated by batch vacuum fractional distillation, and their effect was tested against the dengue fever (DF) vector, known as Aedes aegypti. Furthermore, air freshener gels were formulated with Java citronella oil, carrageenan, gum, sodium benzoate, ethylene glycol, polysorbate 20, sodium chloride, and distilled water, at varying concentrations. The results show that formula I has the best controlled release evaporation for citronellal, citronellol, and geraniol, as well as the best storage time of 16.82 days and 12.77 days for geraniol and citronellol, respectively. The most significant specific gravity (0.0136) was recorded in formula V, while gel formula I exhibited the highest level of instability at 35°C, with a syneresis value of 77.11% in t=72 h and pH 5.33. In addition, formula IV at 5°C demonstrated the highest syneresis (75.34%) in t=72 h, with pH 7.04, while a peak viscosity of 100,958 cP was recorded in formula IV. The repellent activity of each active component was measured based on the period of protection conferred against the bites of Aedes aegypti within one hour, and the results showed geraniol and citronellol, with respective activity of 78.00%±4.83 and 77.34%±3.57, as the most effective.


1995 ◽  
Vol 59 (6) ◽  
pp. 1139-1141 ◽  
Author(s):  
Atsushi Satoh ◽  
Hisashi Utamura ◽  
Teruhiko Nakade ◽  
Hiroyuki Nishimura

Author(s):  
M.M. Miró Specos ◽  
J.J. García ◽  
J. Tornesello ◽  
P. Marino ◽  
M. Della Vecchia ◽  
...  

2017 ◽  
Author(s):  
Ramón García-Domenech ◽  
Maria Angeles Martinez Rodriguez ◽  
Raimundo Segui Lopez-Peñalver ◽  
Gemma Alcacer Tomas ◽  
Jorge Galvez ◽  
...  

2020 ◽  
Vol 981 ◽  
pp. 253-257
Author(s):  
Hazrulrizawati Abd Hamid ◽  
Nishantini Silvarajoo ◽  
Nurulhusna Ab. Hamid

The mosquito Aedes aegypti is an epidemic vector of several diseases such as dengue fever and yellow fever. Several pesticides are used to control the mosquito population. Because of their frequent use, some mosquitoes have developed resistance. In the present study, we evaluated the synergistic mosquito-repellent activity of essential oils from Pelargonium radula, Syzgium aromaticum and Citrus aurantifolia against Aedes aegypti by using Y-tube olfactometer. The oils was subsequently analyzed by using GC–MS. These results clearly reveal that the essential oil of C. aurantifolia served as the most potent repellent agent against Aedes aegypti . The results indicate that three constituents; limonene (19.58%) followed by β–pinene (17.12%), geraniol (13.23%) which comprise a large proportion of the C. aurantifolia are likely responsible for the observed repellent activity.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Narayan Prasad Yadav ◽  
Vineet Kumar Rai ◽  
Nidhi Mishra ◽  
Priyam Sinha ◽  
Dnyaneshwar Umrao Bawankule ◽  
...  

Citronella essential oil (CEO) has been reported as an excellent mosquito repellent; however, mild irritancy and rapid volatility limit its topical application. It was aimed to develop a nonirritant, stable, and consistent cream of CEO with improved residence time on skin using an industrial approach. Phase inversion temperature technique was employed to prepare the cream. It was optimized and characterized based on sensorial evaluation, emulsification, and consistency in terms of softness, greasiness, stickiness, and pH. The optimum batch (B5) was evaluated for viscosity (90249.67 ± 139.95 cP), texture profile with respect to firmness (38.67 ± 0.88 g), spreadability (70.33 ± 0.88 mJ), and extrudability (639.67 ± 8.09 ± 0.1 mJ) using texture analyzer along with two most popular marketed products selected as reference standard. Subsequently, B5 was found to be stable for more than 90 days and showed enhanced duration of mosquito repellency as compared to CEO. HS-GC ensured the intactness of CEO in B5. Investigated primary irritation index (PII 0.45) positioned B5 into the category of irritation barely perceptible. The pronounced texture profile and stability of B5 with extended residence time and less PII revealed its potential application in industry and offered a promising alternative to the marketed products of synthetic origin.


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