scholarly journals A comparative study of the in vitro permeation of ibuprofen in mammalian skin, the PAMPA model and silicone membrane

2016 ◽  
Vol 505 (1-2) ◽  
pp. 14-19 ◽  
Author(s):  
Lin Luo ◽  
Avnish Patel ◽  
Balint Sinko ◽  
Michael Bell ◽  
Judata Wibawa ◽  
...  
Keyword(s):  
Comparative Study ◽  
Silicone Membrane ◽  
In Vitro Permeation ◽  
Mammalian Skin

scholarly journals A comparative study of the in vitro permeation characteristic of sulphadiazine across synthetic membranes and eschar tissue

2008 ◽  
Vol 5 (5) ◽  
pp. 633-638 ◽  
Author(s):  
Behzad Sharif Makhmal Zadeh ◽  
Hamidreza Moghimi ◽  
Paulo Santos ◽  
Jonathan Hadgraft ◽  
Majella E Lane
Keyword(s):  
Comparative Study ◽  
Synthetic Membranes ◽  
In Vitro Permeation

scholarly journals A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model

2019 ◽  
Vol 556 ◽  
pp. 142-149 ◽  
Author(s):  
Yanling Zhang ◽  
Majella E. Lane ◽  
Jonathan Hadgraft ◽  
Michael Heinrich ◽  
Tao Chen ◽  
...  
Keyword(s):  
Membrane Permeation ◽  
Artificial Membrane ◽  
In Vitro Permeation ◽  
Mammalian Skin

Formulation and Evaluation of Carbopol Gel Containing Liposomes of Ketoconazole. (Part-II)

2009 ◽  
Vol 1 (2) ◽  
Author(s):  
Rakesh Patel ◽  
Hardik Patel ◽  
Ashok Baria
Keyword(s):  
Antifungal Activity ◽  
Rat Skin ◽  
Albino Rat ◽  
In Vitro Drug Release ◽  
Carbopol Gel ◽  
Liposomal Formulations ◽  
Release Drug ◽  
In Vitro Permeation ◽  
In Vitro Antifungal Activity

The aim of this work was to prepare and evaluate the topical carbopol gel formulation containing ketoconazole encapsulated liposomes. Ketoconazole loaded liposomes were prepared by thin film hydration technique. The prepared liposomes were incorporated into 1% carbopol gel, and the systems were evaluated for in-vitro drug release, drug retention into skin and in-vitro antifungal activity. The in-vitro permeation of ketoconazole using wistar albino rat skin from liposomal gel was compared with that of plain drug gel and also with plain drug cream containing 2% w/w of ketoconazole. The release of ketoconazole from liposomal gel was much slower than from non liposomal formulations. Gel containing liposomal ketoconazole showed maximum antifungal activity after 30 hours over plain ketoconazole gel and cream formulations.

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