A Phase 2 Trial of Alternative Volumes of Oropharyngeal Irradiation for De-intensification (AVOID): Omission of the Resected Primary Tumor Bed After Transoral Robotic Surgery for Human Papilloma Virus–Related Squamous Cell Carcinoma of the Oropharynx

2020 ◽  
Vol 106 (4) ◽  
pp. 725-732 ◽  
Author(s):  
Samuel Swisher-McClure ◽  
John N. Lukens ◽  
Charu Aggarwal ◽  
Peter Ahn ◽  
Devraj Basu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Robotic Surgery ◽  
Human Papilloma Virus ◽  
Primary Tumor ◽  
Transoral Robotic Surgery ◽  
Phase 2 ◽  
Papilloma Virus ◽  
Tumor Bed ◽  
Phase 2 Trial ◽  
Resected Primary Tumor

scholarly journals Transoral Robotic Surgery for Cancer of the Soft Palate Posterior Surface

2020 ◽  
pp. 014556132097746
Author(s):  
Emilien Chebib ◽  
Jérôme R. Lechien ◽  
Younes Chekkoury ◽  
Stéphane Hans
Keyword(s):  
Squamous Cell Carcinoma ◽  
Surgical Treatment ◽  
Robotic Surgery ◽  
Soft Palate ◽  
Functional Outcomes ◽  
Early Stage ◽  
Tumor Resection ◽  
Transoral Robotic Surgery ◽  
Posterior Surface ◽  
Papilloma Virus

The surgical treatment of oropharyngeal squamous cell carcinoma (OSCC) has undergone a considerable evolution, with, among others, transoral robotic surgery (TORS). However, TORS is rarely used for the surgery of soft palate. A 73-year-old man presented a human papilloma virus OSCC of the posterior soft palate. The tumor was resected using TORS. This report describes the surgical technique step by step of the tumor resection. The resection of early stage OSCC of the posterior surface of soft palate is possible through TORS. The procedure is noninvasive, rapid, and seems to be associated with excellent functional outcomes.

Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma: Improving Function While Maintaining Oncologic Outcome

2020 ◽  
Vol 162 (3) ◽  
pp. 267-268 ◽  
Author(s):  
Daniel W. Scholfield ◽  
Dorothy M. Gujral ◽  
Zaid Awad
Keyword(s):  
Squamous Cell Carcinoma ◽  
Robotic Surgery ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oncologic Outcome ◽  
Transoral Robotic Surgery ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Treatment Algorithms ◽  
Papilloma Virus

The improved survival in patients with HPV-positive (human papilloma virus) oropharyngeal squamous cell carcinoma as compared with HPV-negative disease calls for treatment that preserves quality of life, particularly a functional swallow. There are several trials currently assessing treatment de-escalation in terms of less invasive transoral robotic surgery, reduced-dose radiotherapy, and omission of chemotherapy in this disease cohort. It is important for head and neck oncology surgeons to stay abreast of developments in this area to offer their patients the most up-to-date treatment and consider recruiting patients to trials at their institutions. For this purpose, we provide a summary of current trials and associated challenges in managing a disease with fast-evolving treatment algorithms.

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