scholarly journals The prognostic role of neutrophils to lymphocytes ratio and platelet count in gastric cancer: A meta-analysis

2015 ◽  
Vol 21 ◽  
pp. 84-91 ◽  
Author(s):  
Zhang Xin-Ji ◽  
Liu Yong-Gang ◽  
Shi Xiao-Jun ◽  
Chen Xiao-Wu ◽  
Zhou Dong ◽  
...  
2017 ◽  
Vol 32 (4) ◽  
pp. 447-453 ◽  
Author(s):  
Jung-Soo Pyo ◽  
Nae Yu Kim

Background This meta-analysis aimed to elucidate the prognostic role of the Ki-67 labeling index (LI) in gastric cancer (GC). Methods The current study included 3,615 GC patients in 20 eligible studies, and evaluated the prognostic role of Ki-67 LI in GC. Subgroup analysis was conducted based on depth of invasion and cutoff value for high Ki-67 LI. Results A high Ki-67 LI correlated significantly with worse survival (hazard ratio [HR] = 1.214, 95% confidence interval [CI], 1.004-1.468). However, there was no significant correlation between high Ki-67 LI and worse survival in advanced GC (HR = 1.252, 95% CI, 0.801-1.956). The subgroup with cutoff value ≤25% showed a significant correlation with worse survival, but this was not seen in the subgroup with cutoff >25% (HR = 1.433, 95% CI, 1.094-1.876 vs. HR = 1.005, 95% CI, 0.801-1.262). In addition, in the 10% < Ki-67 LI ≤ 20% range, there was a significant correlation between high Ki-67 LI and worse overall survival (HR = 1.931, 95% CI, 1.013-3.310). Conclusions A high Ki-67 LI correlated significantly with a worse prognosis in GC patients. Further cumulative studies for the optimal cutoff value for high Ki-67 LI are needed before application in clinical practice.


2017 ◽  
Vol 24 (9) ◽  
pp. 2655-2668 ◽  
Author(s):  
Fausto Petrelli ◽  
Michele Ghidini ◽  
Sandro Barni ◽  
Francesca Steccanella ◽  
Giovanni Sgroi ◽  
...  

2013 ◽  
Vol 14 (10) ◽  
pp. 5735-5740 ◽  
Author(s):  
Qing Yu ◽  
Xiong-Fei Yu ◽  
Shou-De Zhang ◽  
Hao-Hao Wang ◽  
Hai-Yong Wang ◽  
...  

2018 ◽  
Vol 57 ◽  
pp. 76-83 ◽  
Author(s):  
Jiang Zhu ◽  
Zhao Xue ◽  
Shumei Zhang ◽  
Xinxin Guo ◽  
Laihui Zhai ◽  
...  

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15559-e15559
Author(s):  
Sashidhar Manthravadi ◽  
Anuj Shrestha ◽  
Sheshadri Madhusudhana

Sign in / Sign up

Export Citation Format

Share Document