Importance of eosinophilic structures and its correlation with acid fast bacilli in fine needle aspiration smears of tubercular lymphadenitis

2021 ◽  
Author(s):  
Shivani Panhotra ◽  
Sabina Khan ◽  
Mohammad Jaseem Hassan ◽  
Sujata Jetley
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Acid Fast Bacilli ◽  
Tubercular Lymphadenitis

scholarly journals Pattern of Lymphadenopathy on Fine Needle Aspiration Cytology in a Tertiary Level Hospital in Kathmandu

2018 ◽  
Vol 1 (2) ◽  
pp. 97-99
Author(s):  
Amar Narayan Shrestha ◽  
Shova Kunwar ◽  
Barun Babu Aryal ◽  
Anurag Adhikari ◽  
Ayusha Poudel
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Tertiary Level ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology ◽  
Tubercular Lymphadenitis ◽  
Level Hospital

Introduction: Fine Needle Aspiration Cytology is a relatively simple, inexpensive and rapid diagnostic procedure for identifying cause of lymphadenopathy without need for surgical procedures. This study aims to explain the pattern of lymphadenopathy seen on fine needle aspiration cytology in a tertiary level hospital in KathmanduMaterials and Methods: This study was conducted at Shree Birendra Hospital Nepal. Cases of lymph node FNAC done in the years 2073 and 2074 BS were included in the study. The cases were classified into reactive lymphadenitis, granulomatous lymphadenitis, tubercular lymphadenitis, lymphomas, leukemias, and metastases.Results: A total of 215 patients were included in the study, ranging in age from 2 to 84 years, out of which 98 were female and 117 were male. Reactive lymphadenitis was the most common diagnosis (n=126; 58.6%), followed by granulomatous lymphadenitis (n=34; 15.8%) and tubercular lymphadenitis (n=18; 8.4%). There were 18 cases of metastatic malignancies, 15 cases of suppurative lymphadenitis, and 2 cases of Hodgkin lymphoma and 2 cases of non-Hodgkin lymphoma.Conclusions: Reactive lymphadenitis is the most common type of lymphadenopathy encountered in FNAC, while in the elderly, metastases are more common.

scholarly journals Correlation between cytomorphology and acid fast bacilli positivity in tubercular lymphadenopathy in far Western Nepal: a hospital based study

2020 ◽  
Vol 8 (8) ◽  
pp. 2933
Author(s):  
Ashok Shreepaili ◽  
Sushil Dhakal
Keyword(s):  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Tuberculous Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Caseous Necrosis ◽  
Needle Aspiration Cytology ◽  
Tubercular Lymphadenitis

Background: Tuberculous lymphadenitis is the most common manifestation of extrapulmonary tuberculosis. Fine needle aspiration cytology (FNAC) is a valuable tool in diagnosis of tubercular lymphadenitis. The present study aims to determine the prevalence of different cytomorphological patterns in fine needle aspiration cytology of tubercular lymph nodes and their correlation with Acid Fast Bacilli (AFB) positivity on Ziehi-Neelsen (ZN) Staining.Methods: Fine needle aspiration cytology of 274 cases diagnosed as tubercular lymphadenitis over a period of a year were reviewed. Cytomorphological patterns were categorized into three patterns. Pattern I: Epithelioid granuloma without necrosis, Pattern II: Epithelioid granuloma with caseous necrosis and Pattern III: Caseous necrosis only. Fischer Exact test was applied to correlate cytomorphological pattern and AFB positivity.Results: Tuberculous lymphadenitis was most frequent in age group 21-30 years (24.81%). Cervical lymph nodes were the most frequent lymph nodes involved (84.67%). Pattern I was the most common cytomorphological pattern observed (49.3%). Overall AFB positivity was 28.10%. Maximum AFB positivity was seen in pattern III (73.3%).Conclusions: FNAC is the simple, cost effective and minimally invasive tool to diagnose tuberculous lymphadenitis. Study of both cytomorphological pattern and ZN staining for AFB can improve the diagnostic accuracy.

scholarly journals Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital

1970 ◽  
Vol 7 (2) ◽  
pp. 139-142 ◽  
Author(s):  
S Hirachand ◽  
M Lakhey ◽  
J Akhter ◽  
B Thapa
Keyword(s):  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
College Teaching ◽  
Needle Aspiration ◽  
Metastatic Carcinoma ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Tubercular Lymphadenitis

Background: Fine Needle Aspiration Cytology (FNAC) is a simple and rapid diagnostic technique. Because of early availability of results, simplicity, minimal trauma and complications, the aspiration cytology is now considered a valuable diagnostic aid and is part and parcel of a pathologist's repertoire. Objectives: The aim of the study was to evaluate the results of fine needle aspiration cytology (FNAC) of lymph nodes in our institution in comparison to result of histopathology. Materials and methods: The present study on 130 patients of lymphadenopathy was conducted in the Department of Pathology Kathmandu Medical College Teaching hospital, Kathmandu from June 2006 to May 2008 (2 years). Results: In this series of FNAC cervical lymph nodes were 66 (50.76%), and axillary lymph nodes were 20 (15.38%). Male to female ratio of the patients was 1: 0.9. Th age of patients ranged from 3 to 85 years. FNAC diagnosis was found to be as follows : reactive hyperplasia 54( 41.55%), tubercular lymphadenitis 36 (28 %), metastatic carcinoma 16 (12.3%), granulomatous lymphadenitis 12 ( 9.2 % ), lymphoma 8 (6%) and suppurative lymphadenitis 4(3%). Out of 28 cases of FNAC 26 (92.85%) were consistent with histopathological diagnosis of tubercular lymphadenitis. In metastatic carcinoma to lymph nodes sensitivity and specificity of FNAC were 100% each. Conclusion: FNAC is useful and reliable in diagnosing neoplastic and non- neoplastic lesions of lymph nodes. It helps in planning surgery for malignant cases, where definitive operative intervention can be performed in one session. Key words: FNAC; lymphadenopathy. DOI: 10.3126/kumj.v7i2.2707 Kathmandu University Medical Journal (2009) Vol.7, No.2 Issue 26,139-142

scholarly journals Incidence of tuberculosis in enlarged neck nodes, our experience

1970 ◽  
Vol 7 (1) ◽  
pp. 54-58 ◽  
Author(s):  
M Maharjan ◽  
S Hirachan ◽  
PK Kafle ◽  
M Bista ◽  
S Shrestha ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
History Of ◽  
Chest X Ray ◽  
Needle Aspiration Cytology ◽  
Anti Tubercular Therapy ◽  
Tubercular Lymphadenitis

Objectives: To determine the incidence of tuberculous lymphadenitis in enlarged neck nodes. Materials and methods: Continuous prospective study is carried out in the department of otorhinolaryngology head & neck surgery, Kathmandu Medical College, Kathmandu, during two years, from January 2006 to January 2008. The study included a group of 155 patients with cervical lymphadenopathy. Each patient underwent a detail clinical Ear, Nose and Throat (ENT) examination and a battery of investigations which included Fine Needle Aspiration Cytology (FNAC) of the nodes, Montoux's test, blood Erythrocyte Sedimentation Rate (ESR) and chest X-ray. Those patients with tubercular lymphadenitis were referred to Directly Observed Therapy System (DOTS) clinic for anti-tubercular therapy. Others with reactive lymphadenitis were treated with antibiotic and those with metastatic neck nodes were treated accordingly. Results: Of the 155 cases with enlarged neck nodes, 83 (54%) had tubercular lymphadenitis. Fifty two (33%) cases had reactive lymphadenitis and 17 (11%) cases were diagnosed with metastatic neck nodes. Fine needle aspiration cytology was found to be highly effective in the diagnosis of tubercular lymphadenitis with 94% accuracy. Majority of patients were otherwise healthy adults, aged between 8 - 71 years. No difference was observed between male and female in this study. Posterior triangle (PT) nodes were most commonly affected group of nodes accounting for 35 (42%) cases and preauricular region 1 (1%) case being the least commonly affected site. Fifteen (18%) cases presented with abscess formation. Only 42 (50%) cases had family history of tuberculosis but 8 (9%) patients had previous history of various forms of tuberculosis. Twelve (14%) patients had positive chest X-ray findings suggesting of concurrent pulmonary tuberculosis. All the patients were referred to DOTS clinic and were treated with category (CAT) - III anti tubercular therapy (ATT). Others with concurrent pulmonary tuberculosis were treated with CAT I regime. None of the patients required surgical treatment. Conclusion: There is high incidence of tubercular cervical lymphadenitis in patients with enlarged neck nodes in developing countries like Nepal. Involvement of cervical lymphnodes are the most commonly affected group of nodes. Therefore, it is important that otolaryngologists are aware of tuberculosis in the head and neck region. Key words: Tuberculosis, Lymph node, Fine needle aspiration cytology, Lymphadenitis    doi: 10.3126/kumj.v7i1.1766       Kathmandu University Medical Journal (2009), Vol. 7, No. 1, Issue 25, 54-58         

Granulomatous epididymo-orchitis: diagnosis by fine needle aspiration

2017 ◽  
Vol 48 (1) ◽  
pp. 17-20
Author(s):  
Uma Handa ◽  
Reetu Kundu ◽  
Gunjan Raghubanshi ◽  
Vidur Bhalla
Keyword(s):  
Retrospective Analysis ◽  
Fine Needle Aspiration ◽  
Granulomatous Inflammation ◽  
Asian Population ◽  
Needle Aspiration ◽  
Epithelioid Cell ◽  
Fine Needle ◽  
Acid Fast Bacilli ◽  
Number Of Patients ◽  
Good Number

Tuberculosis is the leading cause of chronic granulomatous epididymo-orchitis in the Asian population. A retrospective analysis of 40 patients diagnosed with granulomatous or tubercular epididymo-orchitis on fine-needle aspiration (FNA) was carried out. May Grünwald giemsa, haematoxylin and eosin and Ziehl Neelsen stained smears were evaluated. Of 40 patients studied, aspiration smears showed epithelioid cell granulomas with caseation in 17, granulomas alone in 19 and caseation only in four. Acid fast bacilli were seen in 15. Cytologic diagnoses rendered were tubercular epididymo-orchitis in 15, granulomatous inflammation suggestive of tuberculosis in six and granulomatous inflammation in 19. FNA may readily diagnose tubercular epididymo-orchitis and may avoid unnecessary orchidectomy in a good number of patients.

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