Antifungal activity and mechanism of cinnamon essential oil loaded into mesoporous silica nanoparticles

2021 ◽  
Vol 171 ◽  
pp. 113846
Author(s):  
Rongfei Zhang ◽  
Yingjun Cui ◽  
Meng Cheng ◽  
Yanli Guo ◽  
Xiangyou Wang ◽  
...  
2021 ◽  
Vol 17 (6) ◽  
pp. 1242-1248
Author(s):  
Xiao-Hong Yang ◽  
Huan Peng ◽  
Qiu-Lian Hao ◽  
Jian-Ze Wang ◽  
Zhi-Guo Lu ◽  
...  

Depression is a mental disorder characterized by low mood as the main pathological feature. Current medications for depression have long treatment cycles and serious side effects. Aromatherapy can alleviate depression in a “moistening things silently” way, but the fast evaporation rate of aromatic drugs weakens the effect of aromatherapy. In this study, we designed and prepared nano-aromatic drugs with slow release for anti-depressant application. We first synthesized rod-shaped mesoporous silica nanoparticles (MSNs) and encapsulated bergamot essential oil. These nanoaromatic drugs were named BEO@MSNs. Subsequently, we analyzed the pore properties of MSNs and BEO@MSNs. Further, we explored the thermal stability, encapsulation efficiency, and slow-release properties of bergamot essential oil in BEO@MSNs. Finally, we used BEO@MSNs to alleviate depression in mice while constructing depression model mice via corticosterone. The results showed that BEO@MSNs had excellent anti-depressant effects and biosafety


Polymer Korea ◽  
2019 ◽  
Vol 43 (3) ◽  
pp. 327-330
Author(s):  
Min Ah Kim ◽  
Young Eun Yeom ◽  
Dong-Woon Kim ◽  
Jin Kim ◽  
Chang-Moon Lee

2018 ◽  
Vol 5 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Aly Derbalah ◽  
Mohamed Shenashen ◽  
Amany Hamza ◽  
Ahmed Mohamed ◽  
Sherif El Safty

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.


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