scholarly journals Antihypertensive drugs demonstrate varying levels of hip fracture risk: A Systematic Review and Meta-Analysis

Injury ◽  
2021 ◽  
Author(s):  
David W.G. Langerhuizen ◽  
Lukas P.E. Verweij ◽  
Johannes C. van der Wouden ◽  
Gino M.M.J. Kerkhoffs ◽  
Stein J. Janssen
Keyword(s):  
Systematic Review ◽  
Hip Fracture ◽  
Fracture Risk ◽  
Antihypertensive Drugs ◽  
Meta Analysis ◽  
Hip Fracture Risk

scholarly journals The association of fracture risk in atrial fibrillation patients and long-term anticoagulant therapy category: a systematic review and meta-analysis

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e10683
Author(s):  
Jun Chen ◽  
Lingchun Lyu ◽  
Jiayi Shen ◽  
Chunlai Zeng ◽  
Cheng Chen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Systematic Review ◽  
Hip Fracture ◽  
Fracture Risk ◽  
Hip Fractures ◽  
Observational Studies ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Hip Fracture Risk ◽  
Significant Difference

Objective Our study aimed to assess the risk of all fractures and hip fractures in patients with atrial fibrillation (AF) who took non-vitamin K antagonist oral anticoagulants (NOACs) compared to warfarin. Methods We searched PubMed, Embase, and Cochrane Library and Clinical Trials.gov Website. Reviewed related researches up to January 31, 2020, to identify studies with more than 12 months of follow-up data. The protocol for this systematic review and meta-analysis has been registered in the International Prospective Register of Systematic Reviews (PROSPERO Number: CRD42020156893). Results We included five RCT studies, and five observational studies that contained a total of 326,846 patients in our meta-analysis. Our meta-analysis showed that patients taken NOACs had no significant all fracture risk (RR = 0.91, 95% CI [0.81–1.01]) and hip fracture risk (RR = 0.92, 95% CI [0.82–1.03]) compared with those taken warfarin. Subanalysis showed that the risk of all fractures and hip fractures treated by NOACs were significant lower compared with warfarin in observational studies compared with RCT studies. Also, a subanalysis across the duration of anticoagulation showed the NOACs users have lower all fracture risk than warfarin users when the duration of anticoagulation ≤2 years (RR = 0.89, 95% CI [0.80–0.99]). Further analysis, significant lower all fracture risk in the rivaroxaban therapy (RR = 0.81; 95% CI [0.76–0.86]) compared with warfarin but no statistical significance in hip fracture. There were no significant difference of all fracture risk and hip fracture risk in dabigatran, apixaban, and edoxaban therapy compared with warfarin. Conclusion The meta-analysis demonstrated that NOACs associated with a significantly lower all fracture risk compared with warfarin when the duration of anticoagulation more than 2 years. Rivaroxaban users had lower risk of all fracture than warfarin users in AF patients. But there was no evidence to verify apixaban, edoxaban, and dabigatranin could decrease all fracture and hip fracture risk compared with warfarin.

scholarly journals Hip protectors decrease hip fracture risk in elderly nursing home residents: a Bayesian meta-analysis

2007 ◽  
Vol 60 (4) ◽  
pp. 336-344 ◽  
Author(s):  
Anna M. Sawka ◽  
Pauline Boulos ◽  
Karen Beattie ◽  
Alexandra Papaioannou ◽  
Amiram Gafni ◽  
...  
Keyword(s):  
Nursing Home ◽  
Hip Fracture ◽  
Fracture Risk ◽  
Meta Analysis ◽  
Nursing Home Residents ◽  
Hip Protectors ◽  
Hip Fracture Risk

Opioids increase hip fracture risk: a meta-analysis

2016 ◽  
Vol 35 (3) ◽  
pp. 289-297 ◽  
Author(s):  
Fumin Ping ◽  
Ying Wang ◽  
Jing Wang ◽  
Jie Chen ◽  
Wenxian Zhang ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Meta Analysis ◽  
Hip Fracture Risk

scholarly journals The serum 25-hydroxyvitamin D levels and hip fracture risk: a meta-analysis of prospective cohort studies

Oncotarget ◽  
2017 ◽  
Vol 8 (24) ◽  
pp. 39849-39858 ◽  
Author(s):  
Qing-Bo Lv ◽  
Xiang Gao ◽  
Xiang Liu ◽  
Zhen-Xuan Shao ◽  
Qian-Hui Xu ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Cohort Studies ◽  
Fracture Risk ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Hip Fracture Risk ◽  
Hydroxyvitamin D ◽  
Prospective Cohort Studies ◽  
25 Hydroxyvitamin D

scholarly journals Exposure to Fluoride in Drinking Water and Hip Fracture Risk: A Meta-Analysis of Observational Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0126488 ◽  
Author(s):  
Xin-Hai Yin ◽  
Guang-Lei Huang ◽  
Du-Ren Lin ◽  
Cheng-Cheng Wan ◽  
Ya-Dong Wang ◽  
...  
Keyword(s):  
Drinking Water ◽  
Hip Fracture ◽  
Fracture Risk ◽  
Observational Studies ◽  
Meta Analysis ◽  
Hip Fracture Risk

scholarly journals Coffee consumption and hip fracture risk: a meta-analysis

2013 ◽  
Vol 2 ◽  
Author(s):  
Xin-li Li ◽  
Jiu-hong Xu
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Random Effects ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Hip Fracture Risk ◽  
Pubmed Database ◽  
Increased Risk ◽  
Subgroup Analyses

AbstractTo investigate the effect of coffee consumption on hip fracture risk, a meta-analysis was conducted. The PubMed database was screened for all published studies about coffee consumption and hip fracture through to November 2011. Reviews, PubMed option ‘related articles’ and references of retrieved papers were also searched for potentially relevant papers. Only studies that contained OR with 95 % CI for the association between coffee consumption and hip fracture risk were included. The summary risk estimates were calculated by fixed- and random-effects models. Subgroup analyses were carried out stratified by study designs and participant characteristics, respectively. A total of six prospective cohort studies and six case–control studies were included in the final analysis. The pooled OR displayed increased risk of hip fracture by 29·7 % (95 % CI 0·960, 1·751; P = 0·09) for the highest compared with the lowest coffee consumption by the random-effects model (P for heterogeneity = 0·000; I2 = 84·0 %), but the result had no statistical significance. Subgroup analyses showed that coffee consumption significantly increased hip fracture risk by 54·7 % (95 % CI 1·152, 2·077; P = 0·004) among women, by 40·1 % (95 % CI 1·015, 1·935; P = 0·040) for elderly participants aged over 70 years, and by 68·3 % for Northern Americans (95 % CI 1·492, 1·899; P = 0·000). Other subgroup analyses according to data published before the year 2000 showed a positive association between coffee and hip fracture risk, and follow-up duration also positively affected hip fracture risk, especially when the follow-up length was less than 13 years. Although our meta-analysis has provided insufficient evidence that coffee consumption significantly increases hip fracture risk, coffee intake may increase hip fracture risk among women, elderly participants and Northern Americans. No dose–response pattern was observed.

Erratum to: “Hip protectors decrease hip fracture risk in elderly nursing home residents: a Bayesian meta-analysis”

2008 ◽  
Vol 61 (8) ◽  
pp. 854 ◽  
Author(s):  
Anna M. Sawka ◽  
Pauline Boulos ◽  
Karen Beattie ◽  
Alexandra Papaioannou ◽  
Amiram Gafni ◽  
...  
Keyword(s):  
Nursing Home ◽  
Hip Fracture ◽  
Fracture Risk ◽  
Meta Analysis ◽  
Nursing Home Residents ◽  
Hip Protectors ◽  
Hip Fracture Risk
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