3.63 Developmental Trajectories of Gaba Receptor Subunits in Layer 3 Pyramidal and Gaba Neurons in Monkey Visual and Prefrontal Cortices

2018 ◽  
Vol 57 (10) ◽  
pp. S202
Author(s):  
Gil D. Hoftman ◽  
Jennifer N. Burns ◽  
Elizabeth A. Profozich ◽  
Kenneth N. Fish ◽  
David A. Lewis
Keyword(s):  
Gaba Receptor ◽  
Developmental Trajectories ◽  
Gaba Neurons ◽  
Gaba Receptor Subunits ◽  
Prefrontal Cortices

scholarly journals Effects of Kainic Acid on mRNA Expression of GABA, Receptor Subunits in Rat Hippocampus

Epilepsia ◽  
2000 ◽  
Vol 41 (s9) ◽  
pp. 50-50
Author(s):  
Koichi Tsunashima ◽  
Christoph Schwarzer ◽  
Yoshio Minabel ◽  
Nobumasa Kato ◽  
Guenier Sperk
Keyword(s):  
Mrna Expression ◽  
Kainic Acid ◽  
Gaba Receptor ◽  
Rat Hippocampus ◽  
Gaba Receptor Subunits

INVESTIGATION OF THE LEVEL OF GENE EXPRESSION OF SUBUNITS OF GABA RECEPTOR AFTER ADMINISTRATION OF KLOFLUBICIN

2018 ◽  
pp. 33-37
Author(s):  
O. V. Varlamova ◽  
A. V. Babkin ◽  
I. S. Berdinskih ◽  
A. K. Nazarov ◽  
A. S. Sadovnikova ◽  
...  
Keyword(s):  
Gene Expression ◽  
Ion Channel ◽  
Active Substance ◽  
Gaba Receptor ◽  
The Body ◽  
Intramuscular Administration ◽  
Relative Level ◽  
Expression Of Genes ◽  
Genes Encoding ◽  
Gaba Receptor Subunits

The article presents the results of determining the level of expression of genes encoding GABA receptor subunits GABRA1, GABRB2, and GABRG2 in the hippocampus of rats 24 hours after a single intramuscular administration of the antagonist of the chloro-ion channel of GABA receptor of kloflubicin in a dose of LD25, LD40, LD50, and LD75. It is revealed that kloflubicin has no influence on the relative level of GABRG2 gene expression. At the same time, the relative level of GABRA1 gene expression increases 7,5, 7,0, and 5,0 times after administration of kloflubicin in a dose of LD40, LD50, and LD75, respectively. The relative level of GABRB2 gene expression also increases 3,6 and 2,6 times after administration of kloflubicin in a dose of LD50 and LD75, respectively. It is assumed that increase in the level of gene expression of GABRA1 and GABRB2 in rats after administration of kloflubicin in doses above LD25 is a compensatory reaction of the body to the effect of physiologically active substance, and subunits encoded by these genes α1 and β2, respectively, are included in the mechanism of convulsive effect.

Modulation of GABA receptor subunits in rat facial motoneurons after axotomy

2005 ◽  
Vol 135 (1-2) ◽  
pp. 260-275 ◽  
Author(s):  
Isabelle Vassias ◽  
Sylvie Lecolle ◽  
Pierre-Paul Vidal ◽  
Catherine de Waele
Keyword(s):  
Gaba Receptor ◽  
Facial Motoneurons ◽  
Gaba Receptor Subunits
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