35.4 BORDERLINE PERSONALITY FEATURES AND HISTORY OF PRIOR SUICIDE ATTEMPTS DEFINE A SEVERITY GRADIENT IN ADOLESCENT SUICIDE ATTEMPTERS: EVIDENCE FROM A LARGE CROSS-SECTIONAL STUDY OF ADOLESCENT INPATIENTS

Author(s):  
Aveline Aouidad

Author(s):  
Gull Zareen ◽  
Farzana Ashraf ◽  
Admin

Abstract The aim of this study was to determine if suicidal and non-suicidal self-injury can be predicted by the symptoms of Borderline Personality Disorder (BPD) and if non-suicidal self-injury predicts suicidality in young adult females. In this cross-sectional study, 150 undergraduate females (mean age 20.47±3.17) were conveniently sampled and assessed on McLean Screening Instrument for Borderline Personality Disorder, Suicidal Behaviour Questionnaire-Revised, and the Inventory of Statements about Self-injury. Borderline Personality features significantly predicted suicidal ideation and behaviour (?=.383, p<.001) and non-suicidal self-injury (?.282, p<.01). Likewise, non-suicidal self-injury was positively associated with suicidality (r =.330, p<.01). Even sub-threshold BPD features in a non-clinical population may be predictive of suicidal and non-suicidal self-injury. Future research should be based on the management and interventional strategies for tested constructs. Further, screening measures need to be introduced to better detect population at risk of subclinical BPD, suicidal ideation and self-injury. Keywords: Suicidal, Self-injury, Continuous...





2020 ◽  
Vol 25 (4) ◽  
pp. 801-815
Author(s):  
Efrat Malkosh-Tshopp ◽  
Roy Ratzon ◽  
Alex Gizunterman ◽  
Tomer Levy ◽  
David H Ben-Dor ◽  
...  

Religiosity may be a potent protective factor against self-injurious and suicidal behaviors. However, no previous study has addressed this relationship in adolescent psychiatric population. This study aimed to examine the association between religiosity and non-suicidal self-injurious (NSSI) and suicidal behaviors, among hospitalized Jewish adolescents. This is a cross-sectional study of 60 hospitalized Jewish adolescents in two mental health centers. They were evaluated for religiosity, NSSI, and suicidal behaviors. The following religiosity measures were found to be protective against NSSI: a higher degree of adherence to religious practices (extrinsic measure) (beta = −0.083, p = .006), a higher level of belief in religious principles (intrinsic measure) (beta = −0.063, p = .008) and a self-reported higher religious affinity (χ2 = 7.64, p = .022). The severity of suicidal ideation inversely correlated with the extrinsic measure (standardized beta = −0.2, t = −2.5, p = .015) and with self-reported degree of religious affinity (analysis of variance, F = 3.5, p = .035). History of transition in religious affinity was associated with worse suicidal ideation (3.77 ± 1.8 vs. 2.26 ± 1.99, t = −3.25, p = .004) and with suicide attempts (OR = 3.89 (95% CI: 1.08 – 14.03), p = .004); however, these relationships were mediated by history of abuse. This study provides first evidence of a protective effect of some religiosity measures on NSSI and suicidal behaviors in hospitalized Jewish adolescents.



2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Aveline Aouidad ◽  
David Cohen ◽  
Bojan Mirkovic ◽  
Hugues Pellerin ◽  
Sébastien Garny de La Rivière ◽  
...  

Abstract Background Borderline personality disorder (BPD) and history of prior suicide attempt (SA) have been shown to be high predictors for subsequent suicide. However, no previous study has examined how both factors interact to modify clinical and suicide severity among adolescents. Methods This study presents a comprehensive assessment of 302 adolescents (265 girls, mean age = 14.7 years) hospitalized after a SA. To test clinical interactions between BPD and history of prior SA, the sample was divided into single attempters without BPD (non-BPD-SA, N = 80), single attempters with BPD (BPD-SA, N = 127) and multiple attempters with BPD (BPD-MA, N = 95). Results Univariate analyses revealed a severity gradient among the 3 groups with an additive effect of BPD on the clinical and suicide severity already conferred by a history of SA. This gradient encompassed categorical (anxiety and conduct disorders and non-suicidal-self-injury [NSSI]) and dimensional comorbidities (substance use and depression severity) and suicide characteristics (age at first SA). According to regression analyses, the BPD-MA group that was associated with the most severe clinical presentation also showed specific features: the first SA at a younger age and a higher prevalence of non-suicidal self-injury (NSSI) and anxiety disorders. The BPD-MA group was not associated with higher impulsivity or frequency of negative life events. Conclusions Based on these findings and to improve youth suicide prevention, future studies should systematically consider BPD and the efficacy of reinforcing early interventions for anxiety disorders and NSSI.



2011 ◽  
Vol 26 (S2) ◽  
pp. 1642-1642
Author(s):  
T. Seghatoleslam ◽  
H. Habil ◽  
O. Rezaee ◽  
S. Sadr ◽  
R. Emamhadi

BackgroundThe current study aims to test the hypothesis: Is suicide predictable? And try to classify the predictive factors in multiple suicide attempts.MethodA cross-sectional study was administered to 223 multiple attempters, women who came to a medical poison centre after a suicide attempt. The participants were young, poor, and single. A Regression Logistic Test was used to classify the predictive factors of suicide.ResultsWomen who had multiple suicide attempts exhibited a significant tendency to attempt suicide again. They had a history for more than two years of multiple suicide attempts, from three to as many as 18 times, plus mental illnesses such as depression and substance abuse. They also had a positive history of mental illnesses.ConclusionResults indicate that contributing factors for another suicide attempt include previous suicide attempts, mental illness (depression), or a positive history of mental illnesses in the family affecting them at a young age, and substance abuse.



Crisis ◽  
2017 ◽  
Vol 38 (6) ◽  
pp. 367-375 ◽  
Author(s):  
Leo Sher ◽  
Michael F. Grunebaum ◽  
Ainsley K. Burke ◽  
Sadia Chaudhury ◽  
J. John Mann ◽  
...  

Abstract. Background: There is compelling evidence that suicide attempts are among the strongest predictors of suicide and future suicide attempts. Aim: This study aimed to examine psychopathology in multiple-suicide attempters. Method: We compared the demographic and clinical features of three groups: depressed patients without a history of suicide attempts (non-attempters), depressed patients with a history of one to three suicide attempts (attempters), and depressed patients with a history of four or more suicide attempts (multiple attempters). Results: We found that attempters and multiple attempters had higher levels of depression, hopelessness, aggression, hostility, and impulsivity and were more likely to have borderline personality disorder and family history of major depression or alcohol use disorder compared with non-attempters, but did not differ between each other on these measures. Multiple attempters had greater suicidal ideation at study entry and were more likely to have family history of suicide attempt compared with attempters. Importantly, multiple attempters had greater suicide intent at the time of the most medically serious suicide attempt and more serious medical consequences during their most medically serious suicide attempt compared with attempters. Limitations: The cross-sectional design of the study. Conclusion: Our data suggest that multiple-suicide attempters require careful evaluation as their behavior can have serious medical consequences.



Pathogens ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1313
Author(s):  
Cosme Alvarado-Esquivel ◽  
Laura Alejandra Mendoza-Larios ◽  
Fernando García-Dolores ◽  
Luis Francisco Sánchez-Anguiano ◽  
Elizabeth Irasema Antuna-Salcido ◽  
...  

We assessed the association between Toxoplasma gondii (T. gondii) infection of the central nervous system and suicide correlates in suicide decedents. Eighty-seven decedents who died by suicide received in a forensic setting for medico-legal autopsies in Mexico City were studied. Two samples of brain (amygdala and prefrontal cortex) from each decedent were examined for detection of T. gondii using immunohistochemistry. Correlates of suicide including a history of previous suicide attempts, co-morbid mental disorder, consumption of alcohol or tobacco, irritability and aggression, economic problems, presence of drugs or alcohol in blood and suicide method were obtained and analyzed for their association with T. gondii infection. T. gondii immunohistochemistry was positive in prefrontal cortex sections in 6 decedents and in an amygdala section in one decedent. Thus, the prevalence of T. gondii infection in brain in suicide victims was 8.0% (7/87). Bivariate and logistic regression analysis of suicide correlates showed that only a history of depression was associated with T. gondii infection of the brain in suicide victims (OR: 12.00; 95% CI: 2.26–63.46; p = 0.003). Our results provide evidence that T. gondii infection in brain is associated with a history of depression in suicide decedents.



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