scholarly journals Is the Metabolic Syndrome a Cardiovascular Risk Factor Beyond Its Specific Components?

2007 ◽  
Vol 49 (25) ◽  
pp. 2465 ◽  
Author(s):  
Sandro Inchiostro ◽  
Gian Paolo Fadini ◽  
Saula Vigili de Kreutzenberg ◽  
Nadia Citroni ◽  
Angelo Avogaro
2004 ◽  
Vol 57 (6) ◽  
pp. 507-513
Author(s):  
José A. Gimeno Orna ◽  
Luis M. Lou Arnal ◽  
Edmundo Molinero Herguedas ◽  
Beatriz Boned Julián ◽  
Desirée P. Portilla Córdoba

2005 ◽  
Vol 00 (01) ◽  
pp. 31
Author(s):  
Michael Miller

Elevated triglycerides are now considered an independent risk factor for coronary heart disease (CHD), even apart from elevated low-density lipoprotein (LDL) cholesterol. While the primary lipid target for CHD risk management remains LDL cholesterol, the treatment of elevated triglycerides is now also recommended. Elevated triglycerides are believed to increase cardiovascular risk because certain triglyceride-rich lipoproteins, called remnant lipoproteins (partially degraded chylomicrons and very-low density lipoproteins (VLDL)), are atherogenic. Hypertri-glyceridemia, together with low levels of high-density lipoprotein (HDL) cholesterol and an increased prevalence of small, dense LDL particles, comprise a triad of lipid risk factors known as atherogenic dyslipidemia.The significance of hypertriglyceridemia as a cardiovascular risk factor is further highlighted by its inclusion as a component of the metabolic syndrome, a cluster of metabolic abnormalities, related to insulin resistance. The other criteria for metabolic syndrome include low HDL cholesterol, central obesity, elevated blood pressure, and abnormal fasting glucose. The metabolic syndrome is recognized as a major risk factor not only for premature CHD but also for type 2 diabetes mellitus.


2007 ◽  
Vol 66 (5) ◽  
pp. 666-671 ◽  
Author(s):  
G. Neil Thomas ◽  
C. Mary Schooling ◽  
Sarah M. McGhee ◽  
Sai-Yin Ho ◽  
Bernard M. Y. Cheung ◽  
...  

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